| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20067231 | HPV | ENSG00000096968.14 | protein_coding | JAK2 | Yes | No | 3717 | O60674 |
| TVIS20066328 | HPV | ENSG00000096968.14 | protein_coding | JAK2 | Yes | No | 3717 | O60674 |
| TVIS20021822 | HPV | ENSG00000096968.14 | protein_coding | JAK2 | Yes | No | 3717 | O60674 |
| TVIS20021828 | HPV | ENSG00000096968.14 | protein_coding | JAK2 | Yes | No | 3717 | O60674 |
| TVIS20013251 | HPV | ENSG00000096968.14 | protein_coding | JAK2 | Yes | No | 3717 | O60674 |
| TVIS20021829 | HPV | ENSG00000096968.14 | protein_coding | JAK2 | Yes | No | 3717 | O60674 |
| TVIS20026486 | HPV | ENSG00000096968.14 | protein_coding | JAK2 | Yes | No | 3717 | O60674 |
| TVIS20021821 | HPV | ENSG00000096968.14 | protein_coding | JAK2 | Yes | No | 3717 | O60674 |
| TVIS20021824 | HPV | ENSG00000096968.14 | protein_coding | JAK2 | Yes | No | 3717 | O60674 |
| TVIS20063911 | HPV | ENSG00000096968.14 | protein_coding | JAK2 | Yes | No | 3717 | O60674 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | JAK2 |
|---|---|
| DrugBank ID | DB08895 |
| Drug Name | Tofacitinib |
| Target ID | BE0002408 |
| UniProt ID | O60674 |
| Regulation Type | antagonist |
| PubMed IDs | 10592235 |
| Citations | Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. |
| Groups | Approved; Investigational |
| Direct Classification | N-acylpiperidines |
| SMILES | C[C@@H]1CCN(C[C@@H]1N(C)C1=NC=NC2=C1C=CN2)C(=O)CC#N |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL221959 |
