| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20034457 | HPV | ENSG00000132170.24 | protein_coding | PPARG | Yes | No | 5468 | D2KUA6 E9PFX5 P37231 Q4W448 |
| TVIS44022053 | HTLV-1 | ENSG00000132170.24 | protein_coding | PPARG | Yes | No | 5468 | D2KUA6 E9PFX5 P37231 Q4W448 |
| TVIS44006310 | HTLV-1 | ENSG00000132170.24 | protein_coding | PPARG | Yes | No | 5468 | D2KUA6 E9PFX5 P37231 Q4W448 |
| TVIS44022055 | HTLV-1 | ENSG00000132170.24 | protein_coding | PPARG | Yes | No | 5468 | D2KUA6 E9PFX5 P37231 Q4W448 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | PPARG |
|---|---|
| DrugBank ID | DB00412 |
| Drug Name | Rosiglitazone |
| Target ID | BE0000215 |
| UniProt ID | P37231 |
| Regulation Type | agonist |
| PubMed IDs | 10475242; 10548525; 10707565; 10764590; 10871190; 11752352 |
| Citations | Su JL, Winegar DA, Wisely GB, Sigel CS, Hull-Ryde EA: Use of a PPAR gamma-specific monoclonal antibody to demonstrate thiazolidinediones induce PPAR gamma receptor expression in vitro. Hybridoma. 1999 Jun;18(3):273-80.@@Rieusset J, Auwerx J, Vidal H: Regulation of gene expression by activation of the peroxisome proliferator-activated receptor gamma with rosiglitazone (BRL 49653) in human adipocytes. Biochem Biophys Res Commun. 1999 Nov;265(1):265-71.@@Kameda N, Okuya S, Oka Y: [Rosiglitazone (BRL-49653)]. Nihon Rinsho. 2000 Feb;58(2):401-4.@@Johnson BA, Wilson EM, Li Y, Moller DE, Smith RG, Zhou G: Ligand-induced stabilization of PPARgamma monitored by NMR spectroscopy: implications for nuclear receptor activation. J Mol Biol. 2000 Apr 28;298(2):187-94.@@Camp HS, Li O, Wise SC, Hong YH, Frankowski CL, Shen X, Vanbogelen R, Leff T: Differential activation of peroxisome proliferator-activated receptor-gamma by troglitazone and rosiglitazone. Diabetes. 2000 Apr;49(4):539-47.@@Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. |
| Groups | Approved; Investigational |
| Direct Classification | Phenol ethers |
| SMILES | CN(CCOC1=CC=C(CC2SC(=O)NC2=O)C=C1)C1=CC=CC=N1 |
| Pathways | Rosiglitazone Metabolism Pathway |
| PharmGKB | PA451283 |
| ChEMBL | CHEMBL121 |
