| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30084527 | HIV | ENSG00000143839.15 | protein_coding | REN | No | No | 5972 | P00797 |
| TVIS20008388 | HPV | ENSG00000143839.15 | protein_coding | REN | No | No | 5972 | P00797 |
| TVIS44024466 | HTLV-1 | ENSG00000143839.15 | protein_coding | REN | No | No | 5972 | P00797 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | REN |
|---|---|
| DrugBank ID | DB03395 |
| Drug Name | Enalkiren |
| Target ID | BE0000270 |
| UniProt ID | P00797 |
| Regulation Type | inhibitor |
| PubMed IDs | 11752352; 1705633 |
| Citations | Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5.@@Glassman HN, Kleinert HD, Boger RS, Moyse DM, Griffiths AN, Luther RR: Clinical pharmacology of enalkiren, a novel, dipeptide renin inhibitor. J Cardiovasc Pharmacol. 1990;16 Suppl 4:S76-81. |
| Groups | Experimental |
| Direct Classification | Hybrid peptides |
| SMILES | COC1=CC=C(C[C@H](NC(=O)CC(C)(C)N)C(=O)N[C@@H](CC2=CN=CN2)C(=O)N[C@@H](CC2CCCCC2)[C@@H](O)[C@@H](O)CC(C)C)C=C1 |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL300337 |
