| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10002924 | HBV | ENSG00000087088.21 | protein_coding | BAX | No | No | 581 | I6LPK7 Q07812 Q5ZPJ0 Q5ZPJ1 |
| TVIS10002925 | HBV | ENSG00000087088.21 | protein_coding | BAX | No | No | 581 | I6LPK7 Q07812 Q5ZPJ0 Q5ZPJ1 |
| TVIS10022306 | HBV | ENSG00000087088.21 | protein_coding | BAX | No | No | 581 | I6LPK7 Q07812 Q5ZPJ0 Q5ZPJ1 |
| TVIS10028423 | HBV | ENSG00000087088.21 | protein_coding | BAX | No | No | 581 | I6LPK7 Q07812 Q5ZPJ0 Q5ZPJ1 |
| TVIS10022307 | HBV | ENSG00000087088.21 | protein_coding | BAX | No | No | 581 | I6LPK7 Q07812 Q5ZPJ0 Q5ZPJ1 |
| TVIS10028424 | HBV | ENSG00000087088.21 | protein_coding | BAX | No | No | 581 | I6LPK7 Q07812 Q5ZPJ0 Q5ZPJ1 |
| TVIS10052556 | HBV | ENSG00000087088.21 | protein_coding | BAX | No | No | 581 | I6LPK7 Q07812 Q5ZPJ0 Q5ZPJ1 |
| TVIS10052554 | HBV | ENSG00000087088.21 | protein_coding | BAX | No | No | 581 | I6LPK7 Q07812 Q5ZPJ0 Q5ZPJ1 |
| TVIS30007545 | HIV | ENSG00000087088.21 | protein_coding | BAX | No | No | 581 | I6LPK7 Q07812 Q5ZPJ0 Q5ZPJ1 |
| TVIS30049097 | HIV | ENSG00000087088.21 | protein_coding | BAX | No | No | 581 | I6LPK7 Q07812 Q5ZPJ0 Q5ZPJ1 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | BAX |
|---|---|
| DrugBank ID | DB12756 |
| Drug Name | TAK-901 |
| Target ID | BE0010137 |
| UniProt ID | Q07812 |
| Regulation Type | activator |
| PubMed IDs | 28179288 |
| Citations | Murai S, Matuszkiewicz J, Okuzono Y, Miya H, DE Jong R: Aurora B Inhibitor TAK-901 Synergizes with BCL-xL Inhibition by Inducing Active BAX in Cancer Cells. Anticancer Res. 2017 Feb;37(2):437-444. doi: 10.21873/anticanres.11335. |
| Groups | Investigational |
| Direct Classification | Alpha carbolines |
| SMILES | CCS(=O)(=O)C1=CC=CC(=C1)C1=CC(C(=O)NC2CCN(C)CC2)=C(C)C2=C1C1=C(N2)N=CC(C)=C1 |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL3544932 |
