| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30065498 | HIV | ENSG00000118432.13 | protein_coding | CNR1 | No | No | 1268 | P21554 S5TLS4 V5KA96 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | CNR1 |
|---|---|
| DrugBank ID | DB00470 |
| Drug Name | Dronabinol |
| Target ID | BE0000061 |
| UniProt ID | P21554 |
| Regulation Type | agonist |
| PubMed IDs | 17139284; 17016423; 12686391; 11204352; 11752352 |
| Citations | Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Pryce G, Giovannoni G, Baker D: Mifepristone or inhibition of 11beta-hydroxylase activity potentiates the sedating effects of the cannabinoid receptor-1 agonist Delta(9)-tetrahydrocannabinol in mice. Neurosci Lett. 2003 May 1;341(2):164-6.@@Tsai SJ, Wang YC, Hong CJ: Association study of a cannabinoid receptor gene (CNR1) polymorphism and schizophrenia. Psychiatr Genet. 2000 Sep;10(3):149-51.@@Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. |
| Groups | Approved; Illicit |
| Direct Classification | 2,2-dimethyl-1-benzopyrans |
| SMILES | [H][C@@]12C=C(C)CC[C@@]1([H])C(C)(C)OC1=C2C(O)=CC(CCCCC)=C1 |
| Pathways | |
| PharmGKB | PA449421 |
| ChEMBL | CHEMBL465 |
