| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10038074 | HBV | ENSG00000165646.14 | protein_coding | SLC18A2 | No | No | 6571 | Q05940 |
| TVIS10046857 | HBV | ENSG00000165646.14 | protein_coding | SLC18A2 | No | No | 6571 | Q05940 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | SLC18A2 |
|---|---|
| DrugBank ID | DB00182 |
| Drug Name | Amphetamine |
| Target ID | BE0000118 |
| UniProt ID | Q05940 |
| Regulation Type | inhibitor |
| PubMed IDs | 15955613; 7751968; 9648873; 21272013 |
| Citations | Sulzer D, Sonders MS, Poulsen NW, Galli A: Mechanisms of neurotransmitter release by amphetamines: a review. Prog Neurobiol. 2005 Apr;75(6):406-33.@@Sulzer D, Chen TK, Lau YY, Kristensen H, Rayport S, Ewing A: Amphetamine redistributes dopamine from synaptic vesicles to the cytosol and promotes reverse transport. J Neurosci. 1995 May;15(5 Pt 2):4102-8.@@Teng L, Crooks PA, Dwoskin LP: Lobeline displaces [3H]dihydrotetrabenazine binding and releases [3H]dopamine from rat striatal synaptic vesicles: comparison with d-amphetamine. J Neurochem. 1998 Jul;71(1):258-65.@@Eiden LE, Weihe E: VMAT2: a dynamic regulator of brain monoaminergic neuronal function interacting with drugs of abuse. Ann N Y Acad Sci. 2011 Jan;1216:86-98. doi: 10.1111/j.1749-6632.2010.05906.x. |
| Groups | Approved; Illicit; Investigational |
| Direct Classification | Amphetamines and derivatives |
| SMILES | CC(N)CC1=CC=CC=C1 |
| Pathways | |
| PharmGKB | PA448408 |
| ChEMBL | CHEMBL405 |
