| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30078583 | HIV | ENSG00000113749.8 | protein_coding | HRH2 | No | No | 3274 | A0A1B0GTK7 P25021 |
| TVIS20009148 | HPV | ENSG00000113749.8 | protein_coding | HRH2 | No | No | 3274 | A0A1B0GTK7 P25021 |
| TVIS20009386 | HPV | ENSG00000113749.8 | protein_coding | HRH2 | No | No | 3274 | A0A1B0GTK7 P25021 |
| TVIS20059821 | HPV | ENSG00000113749.8 | protein_coding | HRH2 | No | No | 3274 | A0A1B0GTK7 P25021 |
| TVIS44038999 | HTLV-1 | ENSG00000113749.8 | protein_coding | HRH2 | No | No | 3274 | A0A1B0GTK7 P25021 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | HRH2 |
|---|---|
| DrugBank ID | DB00927 |
| Drug Name | Famotidine |
| Target ID | BE0000112 |
| UniProt ID | P25021 |
| Regulation Type | antagonist |
| PubMed IDs | 11752352; 19578661; 2887616 |
| Citations | Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5.@@Inan A, Sen M, Surgit O, Ergin M, Bozer M: Effects of the histamine H2 receptor antagonist famotidine on the healing of colonic anastomosis in rats. Clinics (Sao Paulo). 2009;64(6):567-70.@@Chremos AN: Clinical pharmacology of famotidine: a summary. J Clin Gastroenterol. 1987;9 Suppl 2:7-12. doi: 10.1097/00004836-198707002-00003. |
| Groups | Approved |
| Direct Classification | 2,4-disubstituted thiazoles |
| SMILES | NC(N)=NC1=NC(CSCCC(N)=NS(N)(=O)=O)=CS1 |
| Pathways | Famotidine Action Pathway |
| PharmGKB | PA449586 |
| ChEMBL | CHEMBL902 |
