| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30078583 | HIV | ENSG00000113749.8 | protein_coding | HRH2 | No | No | 3274 | A0A1B0GTK7 P25021 |
| TVIS20009148 | HPV | ENSG00000113749.8 | protein_coding | HRH2 | No | No | 3274 | A0A1B0GTK7 P25021 |
| TVIS20009386 | HPV | ENSG00000113749.8 | protein_coding | HRH2 | No | No | 3274 | A0A1B0GTK7 P25021 |
| TVIS20059821 | HPV | ENSG00000113749.8 | protein_coding | HRH2 | No | No | 3274 | A0A1B0GTK7 P25021 |
| TVIS44038999 | HTLV-1 | ENSG00000113749.8 | protein_coding | HRH2 | No | No | 3274 | A0A1B0GTK7 P25021 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | HRH2 |
|---|---|
| DrugBank ID | DB05381 |
| Drug Name | Histamine |
| Target ID | BE0000112 |
| UniProt ID | P25021 |
| Regulation Type | agonist |
| PubMed IDs | 17334413; 17359382; 11752352 |
| Citations | Francis H, Franchitto A, Ueno Y, Glaser S, DeMorrow S, Venter J, Gaudio E, Alvaro D, Fava G, Marzioni M, Vaculin B, Alpini G: H3 histamine receptor agonist inhibits biliary growth of BDL rats by downregulation of the cAMP-dependent PKA/ERK1/2/ELK-1 pathway. Lab Invest. 2007 May;87(5):473-87. Epub 2007 Mar 5.@@Soga F, Katoh N, Kishimoto S: Histamine prevents apoptosis in human monocytes. Clin Exp Allergy. 2007 Mar;37(3):323-30.@@Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. |
| Groups | Approved; Investigational |
| Direct Classification | 2-arylethylamines |
| SMILES | NCCC1=CNC=N1 |
| Pathways | |
| PharmGKB | PA449880 |
| ChEMBL | CHEMBL90 |