| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10016024 | HBV | ENSG00000077498.9 | protein_coding | TYR | No | No | 7299 | L8B082 P14679 |
| TVIS10026684 | HBV | ENSG00000077498.9 | protein_coding | TYR | No | No | 7299 | L8B082 P14679 |
| TVIS10046898 | HBV | ENSG00000077498.9 | protein_coding | TYR | No | No | 7299 | L8B082 P14679 |
| TVIS20040130 | HPV | ENSG00000077498.9 | protein_coding | TYR | No | No | 7299 | L8B082 P14679 |
| TVIS20068786 | HPV | ENSG00000077498.9 | protein_coding | TYR | No | No | 7299 | L8B082 P14679 |
| TVIS44032379 | HTLV-1 | ENSG00000077498.9 | protein_coding | TYR | No | No | 7299 | L8B082 P14679 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | TYR |
|---|---|
| DrugBank ID | DB00548 |
| Drug Name | Azelaic acid |
| Target ID | BE0000252 |
| UniProt ID | P14679 |
| Regulation Type | inhibitor |
| PubMed IDs | 2114832; 2963038; 4004885; 448162 |
| Citations | Schallreuter KU, Wood JW: A possible mechanism of action for azelaic acid in the human epidermis. Arch Dermatol Res. 1990;282(3):168-71.@@Nazzaro-Porro M: Azelaic acid. J Am Acad Dermatol. 1987 Dec;17(6):1033-41.@@Picardo M, Passi S, Sirianni MC, Fiorilli M, Russo GD, Cortesi E, Barile G, Breathnach AS, Nazzaro-Porro M: Activity of azelaic acid on cultures of lymphoma- and leukemia-derived cell lines, normal resting and stimulated lymphocytes and 3T3 fibroblasts. Biochem Pharmacol. 1985 May 15;34(10):1653-8.@@Nazzaro-Porro M, Passi S, Balus L, Breathnach A, Martin B, Morpurgo G: Effect of dicarboxylic acids on lentigo maligna. J Invest Dermatol. 1979 Jun;72(6):296-305. |
| Groups | Approved |
| Direct Classification | Medium-chain fatty acids |
| SMILES | OC(=O)CCCCCCCC(O)=O |
| Pathways | |
| PharmGKB | PA164754850 |
| ChEMBL | CHEMBL1238 |
