| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10016024 | HBV | ENSG00000077498.9 | protein_coding | TYR | No | No | 7299 | L8B082 P14679 |
| TVIS10026684 | HBV | ENSG00000077498.9 | protein_coding | TYR | No | No | 7299 | L8B082 P14679 |
| TVIS10046898 | HBV | ENSG00000077498.9 | protein_coding | TYR | No | No | 7299 | L8B082 P14679 |
| TVIS20040130 | HPV | ENSG00000077498.9 | protein_coding | TYR | No | No | 7299 | L8B082 P14679 |
| TVIS20068786 | HPV | ENSG00000077498.9 | protein_coding | TYR | No | No | 7299 | L8B082 P14679 |
| TVIS44032379 | HTLV-1 | ENSG00000077498.9 | protein_coding | TYR | No | No | 7299 | L8B082 P14679 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | TYR |
|---|---|
| DrugBank ID | DB11217 |
| Drug Name | Arbutin |
| Target ID | BE0000252 |
| UniProt ID | P14679 |
| Regulation Type | inhibitor |
| PubMed IDs | 8632348; 9711535; 32010471; 31001339; 33224228 |
| Citations | Maeda K, Fukuda M: Arbutin: mechanism of its depigmenting action in human melanocyte culture. J Pharmacol Exp Ther. 1996 Feb;276(2):765-9.@@Chakraborty AK, Funasaka Y, Komoto M, Ichihashi M: Effect of arbutin on melanogenic proteins in human melanocytes. Pigment Cell Res. 1998 Aug;11(4):206-12.@@Im KH, Baek SA, Choi J, Lee TS: Antioxidant, Anti-Melanogenic and Anti-Wrinkle Effects of Phellinus vaninii. Mycobiology. 2019 Oct 15;47(4):494-505. doi: 10.1080/12298093.2019.1673595. eCollection 2019.@@Lu H, Yang K, Zhan L, Lu T, Chen X, Cai X, Zhou C, Li H, Qian L, Lv G, Chen S: Optimization of Flavonoid Extraction in Dendrobium officinale Leaves and Their Inhibitory Effects on Tyrosinase Activity. Int J Anal Chem. 2019 Mar 13;2019:7849198. doi: 10.1155/2019/7849198. eCollection 2019.@@Ghaffarzadeh J, Nasuhi Pur F: Calixarbutin: A Novel Calixarene-based Potential Water-soluble Anti-tyrosinase Agent with High Anti-melanoma Activity. Iran J Pharm Res. 2020 Spring;19(2):236-241. doi: 10.22037/ijpr.2020.112506.13798. |
| Groups | Approved |
| Direct Classification | Phenolic glycosides |
| SMILES | OC[C@H]1O[C@@H](OC2=CC=C(O)C=C2)[C@H](O)[C@@H](O)[C@@H]1O |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL232202 |
