| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10016024 | HBV | ENSG00000077498.9 | protein_coding | TYR | No | No | 7299 | L8B082 P14679 |
| TVIS10026684 | HBV | ENSG00000077498.9 | protein_coding | TYR | No | No | 7299 | L8B082 P14679 |
| TVIS10046898 | HBV | ENSG00000077498.9 | protein_coding | TYR | No | No | 7299 | L8B082 P14679 |
| TVIS20040130 | HPV | ENSG00000077498.9 | protein_coding | TYR | No | No | 7299 | L8B082 P14679 |
| TVIS20068786 | HPV | ENSG00000077498.9 | protein_coding | TYR | No | No | 7299 | L8B082 P14679 |
| TVIS44032379 | HTLV-1 | ENSG00000077498.9 | protein_coding | TYR | No | No | 7299 | L8B082 P14679 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | TYR |
|---|---|
| DrugBank ID | DB01055 |
| Drug Name | Mimosine |
| Target ID | BE0000252 |
| UniProt ID | P14679 |
| Regulation Type | inhibitor |
| PubMed IDs | 15577244; 16750372; 3094574; 6234942 |
| Citations | Ahmad VU, Ullah F, Hussain J, Farooq U, Zubair M, Khan MT, Choudhary MI: Tyrosinase inhibitors from Rhododendron collettianum and their structure-activity relationship (SAR) studies. Chem Pharm Bull (Tokyo). 2004 Dec;52(12):1458-61.@@Khan KM, Mughal UR, Khan MT, Zia-Ullah, Perveen S, Choudhary MI: Oxazolones: new tyrosinase inhibitors; synthesis and their structure-activity relationships. Bioorg Med Chem. 2006 Sep 1;14(17):6027-33. Epub 2006 Jun 5.@@Sugumaran M: Tyrosinase catalyzes an unusual oxidative decarboxylation of 3,4-dihydroxymandelate. Biochemistry. 1986 Aug 12;25(16):4489-92.@@Woolery GL, Powers L, Winkler M, Solomon EI, Lerch K, Spiro TG: Extended X-ray absorption fine structure study of the coupled binuclear copper active site of tyrosinase from Neurospora crassa. Biochim Biophys Acta. 1984 Jul 31;788(2):155-61. |
| Groups | Experimental |
| Direct Classification | L-alpha-amino acids |
| SMILES | N[C@@H](CN1C=CC(=O)C(O)=C1)C(O)=O |
| Pathways | |
| PharmGKB | PA164752445 |
| ChEMBL | CHEMBL245416 |
