| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30058051 | HIV | ENSG00000151577.14 | protein_coding | DRD3 | No | No | 1814 | A1A4V4 E9PCM4 P35462 X5D2G4 |
| TVIS20057150 | HPV | ENSG00000151577.14 | protein_coding | DRD3 | No | No | 1814 | A1A4V4 E9PCM4 P35462 X5D2G4 |
| TVIS20057354 | HPV | ENSG00000151577.14 | protein_coding | DRD3 | No | No | 1814 | A1A4V4 E9PCM4 P35462 X5D2G4 |
| TVIS20040604 | HPV | ENSG00000151577.14 | protein_coding | DRD3 | No | No | 1814 | A1A4V4 E9PCM4 P35462 X5D2G4 |
| TVIS44006680 | HTLV-1 | ENSG00000151577.14 | protein_coding | DRD3 | No | No | 1814 | A1A4V4 E9PCM4 P35462 X5D2G4 |
Target Gene Table
▼
TCGA Plot Options
▼
Drug Information
▼
| Gene | DRD3 |
|---|---|
| DrugBank ID | DB01224 |
| Drug Name | Quetiapine |
| Target ID | BE0000581 |
| UniProt ID | P35462 |
| Regulation Type | ligand |
| PubMed IDs | 17848919; 20392299; 12544369 |
| Citations | Nasrallah HA: Atypical antipsychotic-induced metabolic side effects: insights from receptor-binding profiles. Mol Psychiatry. 2008 Jan;13(1):27-35. Epub 2007 Sep 11.@@Vernaleken I, Janouschek H, Raptis M, Hellmann S, Veselinovic T, Brocheler A, Boy C, Cumming P, Hiemke C, Rosch F, Schafer WM, Grunder G: Dopamine D2/3 receptor occupancy by quetiapine in striatal and extrastriatal areas. Int J Neuropsychopharmacol. 2010 Aug;13(7):951-60. doi: 10.1017/S1461145710000374. Epub 2010 Apr 15.@@Bressan RA, Erlandsson K, Jones HM, Mulligan RS, Ell PJ, Pilowsky LS: Optimizing limbic selective D2/D3 receptor occupancy by risperidone: a [123I]-epidepride SPET study. J Clin Psychopharmacol. 2003 Feb;23(1):5-14. doi: 10.1097/00004714-200302000-00002. |
| Groups | Approved |
| Direct Classification | Dibenzothiazepines |
| SMILES | OCCOCCN1CCN(CC1)C1=NC2=CC=CC=C2SC2=CC=CC=C12 |
| Pathways | Quetiapine H1-Antihistamine Action |
| PharmGKB | PA451201 |
| ChEMBL | CHEMBL716 |
