| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30058051 | HIV | ENSG00000151577.14 | protein_coding | DRD3 | No | No | 1814 | A1A4V4 E9PCM4 P35462 X5D2G4 |
| TVIS20057150 | HPV | ENSG00000151577.14 | protein_coding | DRD3 | No | No | 1814 | A1A4V4 E9PCM4 P35462 X5D2G4 |
| TVIS20057354 | HPV | ENSG00000151577.14 | protein_coding | DRD3 | No | No | 1814 | A1A4V4 E9PCM4 P35462 X5D2G4 |
| TVIS20040604 | HPV | ENSG00000151577.14 | protein_coding | DRD3 | No | No | 1814 | A1A4V4 E9PCM4 P35462 X5D2G4 |
| TVIS44006680 | HTLV-1 | ENSG00000151577.14 | protein_coding | DRD3 | No | No | 1814 | A1A4V4 E9PCM4 P35462 X5D2G4 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | DRD3 |
|---|---|
| DrugBank ID | DB01235 |
| Drug Name | Levodopa |
| Target ID | BE0000581 |
| UniProt ID | P35462 |
| Regulation Type | agonist |
| PubMed IDs | 18549347; 11978145; 9633680 |
| Citations | Onofrj M, Bonanni L, Thomas A: An expert opinion on safinamide in Parkinson's disease. Expert Opin Investig Drugs. 2008 Jul;17(7):1115-25. doi: 10.1517/13543784.17.7.1115 .@@Deleu D, Northway MG, Hanssens Y: Clinical pharmacokinetic and pharmacodynamic properties of drugs used in the treatment of Parkinson's disease. Clin Pharmacokinet. 2002;41(4):261-309.@@Koller WC, Rueda MG: Mechanism of action of dopaminergic agents in Parkinson's disease. Neurology. 1998 Jun;50(6 Suppl 6):S11-4; discussion S44-8. doi: 10.1212/wnl.50.6_suppl_6.s11. |
| Groups | Approved |
| Direct Classification | Tyrosine and derivatives |
| SMILES | N[C@@H](CC1=CC(O)=C(O)C=C1)C(O)=O |
| Pathways | Tyrosine Metabolism; Disulfiram Action Pathway; Aromatic L-Aminoacid Decarboxylase Deficiency; Monoamine Oxidase-A Deficiency (MAO-A); Catecholamine Biosynthesis; Tyrosinemia, Transient, of the Newborn; Hawkinsinuria; Dopamine beta-Hydroxylase Deficiency; Tyrosinemia Type I; Alkaptonuria; Tyrosine Hydroxylase Deficiency |
| PharmGKB | PA450213 |
| ChEMBL | CHEMBL1009 |
