| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10005318 | HBV | ENSG00000196591.12 | protein_coding | HDAC2 | Yes | No | 3066 | Q92769 |
| TVIS30010961 | HIV | ENSG00000196591.12 | protein_coding | HDAC2 | Yes | No | 3066 | Q92769 |
| TVIS20004407 | HPV | ENSG00000196591.12 | protein_coding | HDAC2 | Yes | No | 3066 | Q92769 |
| TVIS44011440 | HTLV-1 | ENSG00000196591.12 | protein_coding | HDAC2 | Yes | No | 3066 | Q92769 |
| TVIS44011749 | HTLV-1 | ENSG00000196591.12 | protein_coding | HDAC2 | Yes | No | 3066 | Q92769 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | HDAC2 |
|---|---|
| DrugBank ID | DB00277 |
| Drug Name | Theophylline |
| Target ID | BE0002366 |
| UniProt ID | Q92769 |
| Regulation Type | activator |
| PubMed IDs | 12070353; 15337792 |
| Citations | Ito K, Lim S, Caramori G, Cosio B, Chung KF, Adcock IM, Barnes PJ: A molecular mechanism of action of theophylline: Induction of histone deacetylase activity to decrease inflammatory gene expression. Proc Natl Acad Sci U S A. 2002 Jun 25;99(13):8921-6. Epub 2002 Jun 17.@@Cosio BG, Tsaprouni L, Ito K, Jazrawi E, Adcock IM, Barnes PJ: Theophylline restores histone deacetylase activity and steroid responses in COPD macrophages. J Exp Med. 2004 Sep 6;200(5):689-95. Epub 2004 Aug 30. |
| Groups | Approved |
| Direct Classification | Xanthines |
| SMILES | CN1C2=C(NC=N2)C(=O)N(C)C1=O |
| Pathways | Caffeine Metabolism |
| PharmGKB | PA451647 |
| ChEMBL | CHEMBL190 |
