| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10005318 | HBV | ENSG00000196591.12 | protein_coding | HDAC2 | Yes | No | 3066 | Q92769 |
| TVIS30010961 | HIV | ENSG00000196591.12 | protein_coding | HDAC2 | Yes | No | 3066 | Q92769 |
| TVIS20004407 | HPV | ENSG00000196591.12 | protein_coding | HDAC2 | Yes | No | 3066 | Q92769 |
| TVIS44011440 | HTLV-1 | ENSG00000196591.12 | protein_coding | HDAC2 | Yes | No | 3066 | Q92769 |
| TVIS44011749 | HTLV-1 | ENSG00000196591.12 | protein_coding | HDAC2 | Yes | No | 3066 | Q92769 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | HDAC2 |
|---|---|
| DrugBank ID | DB00313 |
| Drug Name | Valproic acid |
| Target ID | BE0002366 |
| UniProt ID | Q92769 |
| Regulation Type | inhibitor |
| PubMed IDs | 12840003; 15124690 |
| Citations | Kramer OH, Zhu P, Ostendorff HP, Golebiewski M, Tiefenbach J, Peters MA, Brill B, Groner B, Bach I, Heinzel T, Gottlicher M: The histone deacetylase inhibitor valproic acid selectively induces proteasomal degradation of HDAC2. EMBO J. 2003 Jul 1;22(13):3411-20.@@Gottlicher M: Valproic acid: an old drug newly discovered as inhibitor of histone deacetylases. Ann Hematol. 2004;83 Suppl 1:S91-2. |
| Groups | Approved; Investigational |
| Direct Classification | Methyl-branched fatty acids |
| SMILES | CCCC(CCC)C(O)=O |
| Pathways | Valproic Acid Metabolism Pathway |
| PharmGKB | PA451846 |
| ChEMBL | CHEMBL109 |
