| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10005318 | HBV | ENSG00000196591.12 | protein_coding | HDAC2 | Yes | No | 3066 | Q92769 |
| TVIS30010961 | HIV | ENSG00000196591.12 | protein_coding | HDAC2 | Yes | No | 3066 | Q92769 |
| TVIS20004407 | HPV | ENSG00000196591.12 | protein_coding | HDAC2 | Yes | No | 3066 | Q92769 |
| TVIS44011440 | HTLV-1 | ENSG00000196591.12 | protein_coding | HDAC2 | Yes | No | 3066 | Q92769 |
| TVIS44011749 | HTLV-1 | ENSG00000196591.12 | protein_coding | HDAC2 | Yes | No | 3066 | Q92769 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | HDAC2 |
|---|---|
| DrugBank ID | DB01303 |
| Drug Name | Oxtriphylline |
| Target ID | BE0002366 |
| UniProt ID | Q92769 |
| Regulation Type | activator |
| PubMed IDs | 15337792; 12070353 |
| Citations | Cosio BG, Tsaprouni L, Ito K, Jazrawi E, Adcock IM, Barnes PJ: Theophylline restores histone deacetylase activity and steroid responses in COPD macrophages. J Exp Med. 2004 Sep 6;200(5):689-95. Epub 2004 Aug 30.@@Ito K, Lim S, Caramori G, Cosio B, Chung KF, Adcock IM, Barnes PJ: A molecular mechanism of action of theophylline: Induction of histone deacetylase activity to decrease inflammatory gene expression. Proc Natl Acad Sci U S A. 2002 Jun 25;99(13):8921-6. Epub 2002 Jun 17. |
| Groups | Approved |
| Direct Classification | Xanthines |
| SMILES | C[N+](C)(C)CCO.CN1C2=C([N-]C=N2)C(=O)N(C)C1=O |
| Pathways | |
| PharmGKB | PA164748137 |
| ChEMBL | CHEMBL1200434 |
