| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10010853 | HBV | ENSG00000170214.5 | protein_coding | ADRA1B | No | No | 147 | P35368 |
| TVIS10010854 | HBV | ENSG00000170214.5 | protein_coding | ADRA1B | No | No | 147 | P35368 |
| TVIS20024833 | HPV | ENSG00000170214.5 | protein_coding | ADRA1B | No | No | 147 | P35368 |
| TVIS20065388 | HPV | ENSG00000170214.5 | protein_coding | ADRA1B | No | No | 147 | P35368 |
| TVIS20023848 | HPV | ENSG00000170214.5 | protein_coding | ADRA1B | No | No | 147 | P35368 |
| TVIS44016411 | HTLV-1 | ENSG00000170214.5 | protein_coding | ADRA1B | No | No | 147 | P35368 |
| TVIS44025476 | HTLV-1 | ENSG00000170214.5 | protein_coding | ADRA1B | No | No | 147 | P35368 |
| TVIS44000687 | HTLV-1 | ENSG00000170214.5 | protein_coding | ADRA1B | No | No | 147 | P35368 |
| TVIS44029351 | HTLV-1 | ENSG00000170214.5 | protein_coding | ADRA1B | No | No | 147 | P35368 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | ADRA1B |
|---|---|
| DrugBank ID | DB01162 |
| Drug Name | Terazosin |
| Target ID | BE0000575 |
| UniProt ID | P35368 |
| Regulation Type | antagonist |
| PubMed IDs | 11711348; 11752352; 2988814; 1358918 |
| Citations | Boyle P, Robertson C, Manski R, Padley RJ, Roehrborn CG: Meta-analysis of randomized trials of terazosin in the treatment of benign prostatic hyperplasia. Urology. 2001 Nov;58(5):717-22.@@Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5.@@Simpson P: Stimulation of hypertrophy of cultured neonatal rat heart cells through an alpha 1-adrenergic receptor and induction of beating through an alpha 1- and beta 1-adrenergic receptor interaction. Evidence for independent regulation of growth and beating. Circ Res. 1985 Jun;56(6):884-94.@@Vincent J, Dachman W, Blaschke TF, Hoffman BB: Pharmacological tolerance to alpha 1-adrenergic receptor antagonism mediated by terazosin in humans. J Clin Invest. 1992 Nov;90(5):1763-8. |
| Groups | Approved |
| Direct Classification | N-arylpiperazines |
| SMILES | COC1=C(OC)C=C2C(N)=NC(=NC2=C1)N1CCN(CC1)C(=O)C1CCCO1 |
| Pathways | |
| PharmGKB | PA451612 |
| ChEMBL | CHEMBL611 |
