| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10010853 | HBV | ENSG00000170214.5 | protein_coding | ADRA1B | No | No | 147 | P35368 |
| TVIS10010854 | HBV | ENSG00000170214.5 | protein_coding | ADRA1B | No | No | 147 | P35368 |
| TVIS20024833 | HPV | ENSG00000170214.5 | protein_coding | ADRA1B | No | No | 147 | P35368 |
| TVIS20065388 | HPV | ENSG00000170214.5 | protein_coding | ADRA1B | No | No | 147 | P35368 |
| TVIS20023848 | HPV | ENSG00000170214.5 | protein_coding | ADRA1B | No | No | 147 | P35368 |
| TVIS44016411 | HTLV-1 | ENSG00000170214.5 | protein_coding | ADRA1B | No | No | 147 | P35368 |
| TVIS44025476 | HTLV-1 | ENSG00000170214.5 | protein_coding | ADRA1B | No | No | 147 | P35368 |
| TVIS44000687 | HTLV-1 | ENSG00000170214.5 | protein_coding | ADRA1B | No | No | 147 | P35368 |
| TVIS44029351 | HTLV-1 | ENSG00000170214.5 | protein_coding | ADRA1B | No | No | 147 | P35368 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | ADRA1B |
|---|---|
| DrugBank ID | DB06262 |
| Drug Name | Droxidopa |
| Target ID | BE0000575 |
| UniProt ID | P35368 |
| Regulation Type | agonist |
| PubMed IDs | 17266602; 20412040; 7773533; 8166240 |
| Citations | Bishop MJ: Recent advances in the discovery of alpha1-adrenoceptor agonists. Curr Top Med Chem. 2007;7(2):135-45.@@Du L, Li M: Modeling the interactions between alpha(1)-adrenergic receptors and their antagonists. Curr Comput Aided Drug Des. 2010 Sep;6(3):165-78.@@Testa R, Guarneri L, Poggesi E, Simonazzi I, Taddei C, Leonardi A: Mediation of noradrenaline-induced contractions of rat aorta by the alpha 1B-adrenoceptor subtype. Br J Pharmacol. 1995 Feb;114(4):745-50.@@Izzo NJ Jr, Colucci WS: Regulation of alpha 1B-adrenergic receptor half-life: protein synthesis dependence and effect of norepinephrine. Am J Physiol. 1994 Mar;266(3 Pt 1):C771-5. |
| Groups | Approved; Investigational |
| Direct Classification | Tyrosine and derivatives |
| SMILES | N[C@@H]([C@H](O)C1=CC(O)=C(O)C=C1)C(O)=O |
| Pathways | |
| PharmGKB | PA164748386 |
| ChEMBL | CHEMBL2103827 |
