| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10044531 | HBV | ENSG00000126934.15 | protein_coding | MAP2K2 | Yes | No | 5605 | P36507 |
| TVIS30004704 | HIV | ENSG00000126934.15 | protein_coding | MAP2K2 | Yes | No | 5605 | P36507 |
| TVIS30012505 | HIV | ENSG00000126934.15 | protein_coding | MAP2K2 | Yes | No | 5605 | P36507 |
| TVIS30047381 | HIV | ENSG00000126934.15 | protein_coding | MAP2K2 | Yes | No | 5605 | P36507 |
| TVIS30047382 | HIV | ENSG00000126934.15 | protein_coding | MAP2K2 | Yes | No | 5605 | P36507 |
| TVIS30047383 | HIV | ENSG00000126934.15 | protein_coding | MAP2K2 | Yes | No | 5605 | P36507 |
| TVIS30047384 | HIV | ENSG00000126934.15 | protein_coding | MAP2K2 | Yes | No | 5605 | P36507 |
| TVIS30047385 | HIV | ENSG00000126934.15 | protein_coding | MAP2K2 | Yes | No | 5605 | P36507 |
| TVIS30047386 | HIV | ENSG00000126934.15 | protein_coding | MAP2K2 | Yes | No | 5605 | P36507 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | MAP2K2 |
|---|---|
| DrugBank ID | DB11967 |
| Drug Name | Binimetinib |
| Target ID | BE0004744 |
| UniProt ID | P36507 |
| Regulation Type | inhibitor |
| PubMed IDs | 28587477 |
| Citations | Koelblinger P, Dornbierer J, Dummer R: A review of binimetinib for the treatment of mutant cutaneous melanoma. Future Oncol. 2017 Aug;13(20):1755-1766. doi: 10.2217/fon-2017-0170. Epub 2017 Jun 7. |
| Groups | Approved; Investigational |
| Direct Classification | 3-halobenzoic acids and derivatives |
| SMILES | CN1C=NC2=C(F)C(NC3=CC=C(Br)C=C3F)=C(C=C12)C(=O)NOCCO |
| Pathways | |
| PharmGKB | PA166179867 |
| ChEMBL | CHEMBL3187723 |
