| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10044552 | HBV | ENSG00000169083.18 | protein_coding | AR | Yes | No | 367 | A0A087WUX9 P10275 |
| TVIS10052789 | HBV | ENSG00000169083.18 | protein_coding | AR | Yes | No | 367 | A0A087WUX9 P10275 |
| TVIS30073184 | HIV | ENSG00000169083.18 | protein_coding | AR | Yes | No | 367 | A0A087WUX9 P10275 |
| TVIS44024288 | HTLV-1 | ENSG00000169083.18 | protein_coding | AR | Yes | No | 367 | A0A087WUX9 P10275 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | AR |
|---|---|
| DrugBank ID | DB00621 |
| Drug Name | Oxandrolone |
| Target ID | BE0000132 |
| UniProt ID | P10275 |
| Regulation Type | agonist |
| PubMed IDs | 11392377; 15219414; 17364004; 20230007; 11752352 |
| Citations | Juul A: The effects of oestrogens on linear bone growth. Hum Reprod Update. 2001 May-Jun;7(3):303-13.@@Zhao J, Bauman WA, Huang R, Caplan AJ, Cardozo C: Oxandrolone blocks glucocorticoid signaling in an androgen receptor-dependent manner. Steroids. 2004 May;69(5):357-66.@@Bi LX, Wiren KM, Zhang XW, Oliveira GV, Klein GL, Mainous EG, Herndon DN: The effect of oxandrolone treatment on human osteoblastic cells. J Burns Wounds. 2007 Mar 7;6:e4.@@Cadwallader AB, Rollins DE, Lim CS: Effect of anabolic-androgenic steroids and glucocorticoids on the kinetics of hAR and hGR nucleocytoplasmic translocation. Mol Pharm. 2010 Jun 7;7(3):689-98. doi: 10.1021/mp900259w.@@Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. |
| Groups | Approved; Investigational |
| Direct Classification | Steroid lactones |
| SMILES | [H][C@@]12CC[C@](C)(O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC[C@@]2([H])CC(=O)OC[C@]12C |
| Pathways | |
| PharmGKB | PA164749395 |
| ChEMBL | CHEMBL1200436 |
