| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10037354 | HBV | ENSG00000080644.16 | protein_coding | CHRNA3 | No | No | 1136 | P32297 |
| TVIS10032120 | HBV | ENSG00000080644.16 | protein_coding | CHRNA3 | No | No | 1136 | P32297 |
| TVIS10039140 | HBV | ENSG00000080644.16 | protein_coding | CHRNA3 | No | No | 1136 | P32297 |
| TVIS30039129 | HIV | ENSG00000080644.16 | protein_coding | CHRNA3 | No | No | 1136 | P32297 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | CHRNA3 |
|---|---|
| DrugBank ID | DB01156 |
| Drug Name | Bupropion |
| Target ID | BE0003585 |
| UniProt ID | P32297 |
| Regulation Type | antagonist |
| PubMed IDs | 9862757; 10991997 |
| Citations | Fryer JD, Lukas RJ: Noncompetitive functional inhibition at diverse, human nicotinic acetylcholine receptor subtypes by bupropion, phencyclidine, and ibogaine. J Pharmacol Exp Ther. 1999 Jan;288(1):88-92.@@Slemmer JE, Martin BR, Damaj MI: Bupropion is a nicotinic antagonist. J Pharmacol Exp Ther. 2000 Oct;295(1):321-7. |
| Groups | Approved |
| Direct Classification | Alkyl-phenylketones |
| SMILES | CC(NC(C)(C)C)C(=O)C1=CC(Cl)=CC=C1 |
| Pathways | |
| PharmGKB | PA448687 |
| ChEMBL | CHEMBL894 |
