|
Phenotypic Information (metabolism pathway, cancer, disease, phenome) | |
Gene-Gene Network Information: Co-Expression Network, Interacting Genes & KEGG | |
Gene Summary for CSGALNACT2 |
Top |
Phenotypic Information for CSGALNACT2(metabolism pathway, cancer, disease, phenome) |
![]() | |
Cancer | CGAP: CSGALNACT2 |
Familial Cancer Database: CSGALNACT2 |
* This gene is included in those cancer gene databases. |
Oncogene 1 | Significant driver gene in |
cf) number; DB name 1 Oncogene; http://nar.oxfordjournals.org/content/35/suppl_1/D721.long, 2 Tumor Suppressor gene; https://bioinfo.uth.edu/TSGene/, 3 Cancer Gene Census; http://www.nature.com/nrc/journal/v4/n3/abs/nrc1299.html, 4 CancerGenes; http://nar.oxfordjournals.org/content/35/suppl_1/D721.long, 5 Network of Cancer Gene; http://ncg.kcl.ac.uk/index.php, 1Therapeutic Vulnerabilities in Cancer; http://cbio.mskcc.org/cancergenomics/statius/ |
![]() | |
REACTOME_METABOLISM_OF_CARBOHYDRATES |
Mutations for CSGALNACT2 |
* Under tables are showing count per each tissue to give us broad intuition about tissue specific mutation patterns.You can go to the detailed page for each mutation database's web site. |
![]() |
There's no structural variation information in COSMIC data for this gene. |
![]() |
* From mRNA Sanger sequences, Chitars2.0 arranged chimeric transcripts. This table shows CSGALNACT2 related fusion information. |
ID | Head Gene | Tail Gene | Accession | Gene_a | qStart_a | qEnd_a | Chromosome_a | tStart_a | tEnd_a | Gene_a | qStart_a | qEnd_a | Chromosome_a | tStart_a | tEnd_a |
DA381927 | CSGALNACT2 | 1 | 396 | 10 | 43651063 | 43654362 | ACKR3 | 397 | 552 | 2 | 237478468 | 237489138 | |
CN418454 | CSGALNACT2 | 1 | 143 | 10 | 43633949 | 43650420 | PDXDC1 | 142 | 599 | 16 | 15227443 | 15228118 | |
BQ637932 | CSGALNACT2 | 1 | 537 | 10 | 43650609 | 43651145 | CDR2 | 534 | 621 | 16 | 22357678 | 22357765 |
![]() |
Top |
![]() |
Mutation type/ Tissue ID | brca | cns | cerv | endome | haematopo | kidn | Lintest | liver | lung | ns | ovary | pancre | prost | skin | stoma | thyro | urina | |||
Total # sample |   |   |   |   |   |   |   |   | 1 |   |   |   |   |   |   |   |   | |||
GAIN (# sample) |   |   |   |   |   |   |   |   | 1 |   |   |   |   |   |   |   |   | |||
LOSS (# sample) |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
cf) Tissue ID; Tissue type (1; Breast, 2; Central_nervous_system, 3; Cervix, 4; Endometrium, 5; Haematopoietic_and_lymphoid_tissue, 6; Kidney, 7; Large_intestine, 8; Liver, 9; Lung, 10; NS, 11; Ovary, 12; Pancreas, 13; Prostate, 14; Skin, 15; Stomach, 16; Thyroid, 17; Urinary_tract) |
Top |
![]() |
|
![]() |
Top |
![]() |
Stat. for Non-Synonymous SNVs (# total SNVs=65) | (# total SNVs=17) |
![]() | ![]() |
(# total SNVs=1) | (# total SNVs=0) |
![]() |
Top |
![]() |
* When you move the cursor on each content, you can see more deailed mutation information on the Tooltip. Those are primary_site,primary_histology,mutation(aa),pubmedID. |
GRCh37 position | Mutation(aa) | Unique sampleID count |
chr10:43659419-43659419 | p.L362F | 8 |
chr10:43659338-43659338 | p.T335T | 4 |
chr10:43654172-43654172 | p.R224H | 3 |
chr10:43678796-43678796 | p.P479S | 3 |
chr10:43651251-43651251 | p.F218F | 3 |
chr10:43662538-43662538 | p.Q416K | 2 |
chr10:43650762-43650762 | p.E55D | 2 |
chr10:43659339-43659339 | p.L336V | 2 |
chr10:43678849-43678849 | p.P496P | 2 |
chr10:43651233-43651233 | p.I212M | 2 |
Top |
![]() |
|
![]() |
Point Mutation/ Tissue ID | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 |
# sample | 2 | 2 |   | 8 |   |   | 4 |   | 3 | 2 |   | 11 | 3 | 1 |   |   | 7 | 3 | 3 | 12 |
# mutation | 2 | 2 |   | 9 |   |   | 4 |   | 3 | 2 |   | 14 | 3 | 1 |   |   | 10 | 3 | 3 | 14 |
nonsynonymous SNV | 1 | 2 |   | 8 |   |   | 3 |   | 3 | 1 |   | 11 | 3 | 1 |   |   | 4 | 2 | 1 | 10 |
synonymous SNV | 1 |   |   | 1 |   |   | 1 |   |   | 1 |   | 3 |   |   |   |   | 6 | 1 | 2 | 4 |
cf) Tissue ID; Tissue type (1; BLCA[Bladder Urothelial Carcinoma], 2; BRCA[Breast invasive carcinoma], 3; CESC[Cervical squamous cell carcinoma and endocervical adenocarcinoma], 4; COAD[Colon adenocarcinoma], 5; GBM[Glioblastoma multiforme], 6; Glioma Low Grade, 7; HNSC[Head and Neck squamous cell carcinoma], 8; KICH[Kidney Chromophobe], 9; KIRC[Kidney renal clear cell carcinoma], 10; KIRP[Kidney renal papillary cell carcinoma], 11; LAML[Acute Myeloid Leukemia], 12; LUAD[Lung adenocarcinoma], 13; LUSC[Lung squamous cell carcinoma], 14; OV[Ovarian serous cystadenocarcinoma ], 15; PAAD[Pancreatic adenocarcinoma], 16; PRAD[Prostate adenocarcinoma], 17; SKCM[Skin Cutaneous Melanoma], 18:STAD[Stomach adenocarcinoma], 19:THCA[Thyroid carcinoma], 20:UCEC[Uterine Corpus Endometrial Carcinoma]) |
Top |
![]() |
* We represented just top 10 SNVs. When you move the cursor on each content, you can see more deailed mutation information on the Tooltip. Those are primary_site, primary_histology, mutation(aa), pubmedID. |
Genomic Position | Mutation(aa) | Unique sampleID count |
chr10:43654172 | p.R224L | 2 |
chr10:43654238 | p.R246T | 2 |
chr10:43662538 | p.P496P | 2 |
chr10:43651086 | p.Q416K | 2 |
chr10:43678849 | p.L163L | 2 |
chr10:43650712 | p.V47I | 1 |
chr10:43655966 | p.E169G | 1 |
chr10:43650986 | p.T335T | 1 |
chr10:43662509 | p.G447V | 1 |
chr10:43678742 | p.E55E | 1 |
![]() |
![]() |
* Copy number data were extracted from TCGA using R package TCGA-Assembler. The URLs of all public data files on TCGA DCC data server were gathered on Jan-05-2015. Function ProcessCNAData in TCGA-Assembler package was used to obtain gene-level copy number value which is calculated as the average copy number of the genomic region of a gene. |
![]() |
cf) Tissue ID[Tissue type]: BLCA[Bladder Urothelial Carcinoma], BRCA[Breast invasive carcinoma], CESC[Cervical squamous cell carcinoma and endocervical adenocarcinoma], COAD[Colon adenocarcinoma], GBM[Glioblastoma multiforme], Glioma Low Grade, HNSC[Head and Neck squamous cell carcinoma], KICH[Kidney Chromophobe], KIRC[Kidney renal clear cell carcinoma], KIRP[Kidney renal papillary cell carcinoma], LAML[Acute Myeloid Leukemia], LUAD[Lung adenocarcinoma], LUSC[Lung squamous cell carcinoma], OV[Ovarian serous cystadenocarcinoma ], PAAD[Pancreatic adenocarcinoma], PRAD[Prostate adenocarcinoma], SKCM[Skin Cutaneous Melanoma], STAD[Stomach adenocarcinoma], THCA[Thyroid carcinoma], UCEC[Uterine Corpus Endometrial Carcinoma] |
Top |
Gene Expression for CSGALNACT2 |
![]() |
* CCLE gene expression data were extracted from CCLE_Expression_Entrez_2012-10-18.res: Gene-centric RMA-normalized mRNA expression data. |
![]() |
![]() |
* Normalized gene expression data of RNASeqV2 was extracted from TCGA using R package TCGA-Assembler. The URLs of all public data files on TCGA DCC data server were gathered at Jan-05-2015. Only eight cancer types have enough normal control samples for differential expression analysis. (t test, adjusted p<0.05 (using Benjamini-Hochberg FDR)) |
![]() |
Top |
![]() |
* This plots show the correlation between CNV and gene expression. |
![]() | |
![]() |
Top |
Gene-Gene Network Information |
![]() |
* Co-Expression network figures were drawn using R package igraph. Only the top 20 genes with the highest correlations were shown. Red circle: input gene, orange circle: cell metabolism gene, sky circle: other gene |
![]() | |
BACH1,BICC1,CLIC4,CSGALNACT2,DDX21,DSE,FERMT2, FUT11,ITGB1,KCTD20,LATS2,LIMS1,LOX,MAP3K2, PLXNC1,QKI,RIF1,RRAGC,SEC23A,SGTB,ZNF699 | ACAP2,ACTR2,ATP11C,BNIP2,CCDC88A,CDC27,CEP170, CSGALNACT2,EEA1,EXOC5,GNA13,KIAA1033,BLOC1S6,RAB8B, RBMS1,RECQL,SGMS1,SGTB,SOCS4,SYNJ1,TMX3 |
![]() | |
VSTM4,C1S,CSGALNACT2,DZIP1,ENTPD1,EVC,FSTL1, GAS7,GNB4,GPC6,LUM,MAF,MCC,NR3C1, PDGFRB,PKD2,QKI,SULF1,TCF4,ZEB2,ZNF521 | CALU,CEP170,CHN1,CSGALNACT2,DENND5A,ELOVL5,FKBP14, GPR155,HECTD2,KCNE4,SLC9B2,PITPNB,PRKD3,QKI, RAB11FIP2,RBMS1,RHOQ,SLC39A6,TBCEL,TCEAL4,TCF4 |
![]() |
* Co-Expression network figures were drawn using R package igraph. Only the top 20 genes with the highest correlations were shown. Red circle: input gene, orange circle: cell metabolism gene, sky circle: other gene |
Top |
![]() |
Top |
Pharmacological Information for CSGALNACT2 |
There's no related Drug. |
Top |
Cross referenced IDs for CSGALNACT2 |
* We obtained these cross-references from Uniprot database. It covers 150 different DBs, 18 categories. http://www.uniprot.org/help/cross_references_section |
Copyright © 2016-Present - The Univsersity of Texas Health Science Center at Houston @ |