Cancer Cell Metabolism Gene Database

  Cancer Cell Metabolism Gene DB

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Bioinformatics and Systems Medicine Laboratory Bioinformatics and Systems Medicine Laboratory

Gene Summary

Phenotypic Information (metabolism pathway, cancer, disease, phenome)

Mutations: SVs, CNVs, SNVs

Gene expression: GE, Protein, DEGE, CNV vs GE

Gene-Gene Network Information: Co-Expression Network, Interacting Genes & KEGG

Pharmacological Information: Drug-Gene Network

Cross referenced IDs

Gene Summary for CA2
Basic gene info.Gene symbolCA2
Gene namecarbonic anhydrase II
SynonymsCA-II|CAC|CAII|Car2|HEL-76
CytomapUCSC genome browser: 8q22
Genomic locationchr8 :86376130-86393721
Type of geneprotein-coding
RefGenesNM_000067.2,
NM_001293675.1,
Ensembl idENSG00000104267
Descriptioncarbonate dehydratase IIcarbonic anhydrase 2carbonic anhydrase Bcarbonic anhydrase Ccarbonic dehydrataseepididymis luminal protein 76
Modification date20141221
dbXrefs MIM : 611492
HGNC : HGNC
Ensembl : ENSG00000104267
HPRD : 02023
Vega : OTTHUMG00000164944
ProteinUniProt: P00918
go to UniProt's Cross Reference DB Table
ExpressionCleanEX: HS_CA2
BioGPS: 760
Gene Expression Atlas: ENSG00000104267
The Human Protein Atlas: ENSG00000104267
PathwayNCI Pathway Interaction Database: CA2
KEGG: CA2
REACTOME: CA2
ConsensusPathDB
Pathway Commons: CA2
MetabolismMetaCyc: CA2
HUMANCyc: CA2
RegulationEnsembl's Regulation: ENSG00000104267
miRBase: chr8 :86,376,130-86,393,721
TargetScan: NM_000067
cisRED: ENSG00000104267
ContextiHOP: CA2
cancer metabolism search in PubMed: CA2
UCL Cancer Institute: CA2
Assigned class in ccmGDBA - This gene has a literature evidence and it belongs to cancer gene.
References showing role of CA2 in cancer cell metabolism1. Sheng W, Dong M, Zhou J, Li X, Dong Q (2013) Down regulation of CAII is associated with tumor differentiation and poor prognosis in patients with pancreatic cancer. J Surg Oncol 107: 536-543. doi: 10.1002/jso.23282. go to article
2. Zhou R, Huang W, Yao Y, Wang Y, Li Z, et al. (2013) CA II, a potential biomarker by proteomic analysis, exerts significant inhibitory effect on the growth of colorectal cancer cells. Int J Oncol 43: 611-621. doi: 10.3892/ijo.2013.1972. go to article

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Phenotypic Information for CA2(metabolism pathway, cancer, disease, phenome)
check002.gifCancer Description
Cancer CGAP: CA2
Familial Cancer Database: CA2
* This gene is included in those cancer gene databases.

Oncogene 1

Tumor Suppressor gene 2

Cancer Gene Census 3

CancerGenes 4

Network of Cancer Gene 5

Significant driver gene in

Therapeutic Vulnerabilities in Cancer1

cf) number; DB name
1 Oncogene; http://nar.oxfordjournals.org/content/35/suppl_1/D721.long,
2 Tumor Suppressor gene; https://bioinfo.uth.edu/TSGene/,
3 Cancer Gene Census; http://www.nature.com/nrc/journal/v4/n3/abs/nrc1299.html,
4 CancerGenes; http://nar.oxfordjournals.org/content/35/suppl_1/D721.long,
5 Network of Cancer Gene; http://ncg.kcl.ac.uk/index.php,
1Therapeutic Vulnerabilities in Cancer; http://cbio.mskcc.org/cancergenomics/statius/

check002.gifMetabolic Pathway Description
KEGG_NITROGEN_METABOLISM

check002.gifOthers
OMIM 259730; phenotype.
611492; gene.
Orphanet 2785; Osteopetrosis with renal tubular acidosis.
DiseaseKEGG Disease: CA2
MedGen: CA2 (Human Medical Genetics with Condition)
ClinVar: CA2
PhenotypeMGI: CA2 (International Mouse Phenotyping Consortium)
PhenomicDB: CA2

Mutations for CA2
* Under tables are showing count per each tissue to give us broad intuition about tissue specific mutation patterns.You can go to the detailed page for each mutation database's web site.

check002.gifStructural Variants in COSMIC: go to COSMIC mutation histogram

- Statistics for Tissue and Mutation typeTop
- For Inter-chromosomal Variations
There's no inter-chromosomal structural variation.
- For Intra-chromosomal Variations
* Intra-chromosomal variantions includes 'intrachromosomal amplicon to amplicon', 'intrachromosomal amplicon to non-amplified dna', 'intrachromosomal deletion', 'intrachromosomal fold-back inversion', 'intrachromosomal inversion', 'intrachromosomal tandem duplication', 'Intrachromosomal unknown type', 'intrachromosomal with inverted orientation', 'intrachromosomal with non-inverted orientation'.
SampleSymbol_aChr_aStart_aEnd_aSymbol_bChr_bStart_bEnd_b
ovaryCA2chr88638564886385668chr8107841578107841598
ovaryCA2chr88638564986385669chr8107841772107841792
ovaryCA2chr88638564986385669chr8107841776107841796
cf) Tissue number; Tissue name (1;Breast, 2;Central_nervous_system, 3;Haematopoietic_and_lymphoid_tissue, 4;Large_intestine, 5;Liver, 6;Lung, 7;Ovary, 8;Pancreas, 9;Prostate, 10;Skin, 11;Soft_tissue, 12;Upper_aerodigestive_tract)

check002.gifRelated fusion transcripts : go to Chitars2.0
* From mRNA Sanger sequences, Chitars2.0 arranged chimeric transcripts. This table shows CA2 related fusion information.
IDHead GeneTail Gene
AccessionGene_aqStart_aqEnd_aChromosome_atStart_atEnd_aGene_aqStart_aqEnd_aChromosome_atStart_atEnd_a
BI042447MSC1621487275421372754411CA221236988638594986386618

check002.gifOther DBs for Structural Variants
Structural Variants in Ensembl: go to Ensembl Structural variation
Structural Variants in dbVar: go to dbVar

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check002.gifCopy Number Variations in COSMIC: go to COSMIC mutation CNV/Expr
 
Mutation type/ Tissue IDbrcacnscervendomehaematopokidnLintestliverlungnsovarypancreprostskinstomathyrourina
Total # sample1       1    1   
GAIN (# sample)1       1    1   
LOSS (# sample)                 
cf) Tissue ID; Tissue type (1; Breast, 2; Central_nervous_system, 3; Cervix, 4; Endometrium, 5; Haematopoietic_and_lymphoid_tissue, 6; Kidney, 7; Large_intestine, 8; Liver, 9; Lung, 10; NS, 11; Ovary, 12; Pancreas, 13; Prostate, 14; Skin, 15; Stomach, 16; Thyroid, 17; Urinary_tract)

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check002.gifSNV Counts per Each Loci in COSMIC data: go to COSMIC point mutation

 : Non-synonymous mutation, : Synonymous mutation, Circle size denotes number of samples.
Maximum mutation count=3

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check002.gifSomatic Mutation Counts per Tissue in COSMIC data
Stat. for Non-Synonymous SNVs
(# total SNVs=23)		Stat. for Synonymous SNVs
(# total SNVs=1)
Stat. for Deletions
(# total SNVs=1)		Stat. for Insertions
(# total SNVs=0)
There's no inserted snv.

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check002.gifTop 10 SNVs Having the Most Samples in COSMIC data
* When you move the cursor on each content, you can see more deailed mutation information on the Tooltip. Those are primary_site,primary_histology,mutation(aa),pubmedID.
GRCh37 positionMutation(aa)Unique sampleID count
chr8:86389490-86389490p.V217I3
chr8:86392911-86392911p.R226C3
chr8:86389380-86389380p.P180H2
chr8:86389385-86389385p.G182R2
chr8:86392932-86392932p.E233K2
chr8:86392979-86392979p.Q248H1
chr8:86386011-86386011p.T108S1
chr8:86388066-86388066p.V162L1
chr8:86389478-86389478p.E213K1
chr8:86377599-86377599p.K45E1

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check002.gifSNV Counts per Each Loci in TCGA data

 : non-synonymous mutation, : synonymous mutation, Circle size denotes number of samples.
maximum mutation count=2

Point Mutation/ Tissue ID1234567891011121314151617181920
# sample 113  3    3   1113 2
# mutation 113  3    3   1133 2
nonsynonymous SNV 113  1    3   192 2
synonymous SNV      2         41  
cf) Tissue ID; Tissue type (1; BLCA[Bladder Urothelial Carcinoma], 2; BRCA[Breast invasive carcinoma], 3; CESC[Cervical squamous cell carcinoma and endocervical adenocarcinoma], 4; COAD[Colon adenocarcinoma], 5; GBM[Glioblastoma multiforme], 6; Glioma Low Grade, 7; HNSC[Head and Neck squamous cell carcinoma], 8; KICH[Kidney Chromophobe], 9; KIRC[Kidney renal clear cell carcinoma], 10; KIRP[Kidney renal papillary cell carcinoma], 11; LAML[Acute Myeloid Leukemia], 12; LUAD[Lung adenocarcinoma], 13; LUSC[Lung squamous cell carcinoma], 14; OV[Ovarian serous cystadenocarcinoma ], 15; PAAD[Pancreatic adenocarcinoma], 16; PRAD[Prostate adenocarcinoma], 17; SKCM[Skin Cutaneous Melanoma], 18:STAD[Stomach adenocarcinoma], 19:THCA[Thyroid carcinoma], 20:UCEC[Uterine Corpus Endometrial Carcinoma])

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check002.gifTop 10 SNVs Having the Most Samples in TCGA data
* We represented just top 10 SNVs. When you move the cursor on each content, you can see more deailed mutation information on the Tooltip. Those are primary_site, primary_histology, mutation(aa), pubmedID.
Genomic PositionMutation(aa)Unique sampleID count
chr8:86389385p.G81R,CA22
chr8:86386612p.V105V,CA21
chr8:86392938p.H96Q1
chr8:86385963p.W107C,CA21
chr8:86386616p.W97L1
chr8:86392975p.R125C,CA21
chr8:86385977p.K112N1
chr8:86389382p.G131G,CA21
chr8:86385979p.H21Y,CA21
chr8:86386025p.E134K,CA21

check002.gifOther DBs for Point Mutations
Point Mutation Table of Ensembl: go to Ensembl variation table
Mutation of cBioPortal: go to cBioPortal's Cross-cancer alteration summary

check002.gifCopy Number for CA2 in TCGA
* Copy number data were extracted from TCGA using R package TCGA-Assembler. The URLs of all public data files on TCGA DCC data server were gathered on Jan-05-2015. Function ProcessCNAData in TCGA-Assembler package was used to obtain gene-level copy number value which is calculated as the average copy number of the genomic region of a gene.
cf) Tissue ID[Tissue type]: BLCA[Bladder Urothelial Carcinoma], BRCA[Breast invasive carcinoma], CESC[Cervical squamous cell carcinoma and endocervical adenocarcinoma], COAD[Colon adenocarcinoma], GBM[Glioblastoma multiforme], Glioma Low Grade, HNSC[Head and Neck squamous cell carcinoma], KICH[Kidney Chromophobe], KIRC[Kidney renal clear cell carcinoma], KIRP[Kidney renal papillary cell carcinoma], LAML[Acute Myeloid Leukemia], LUAD[Lung adenocarcinoma], LUSC[Lung squamous cell carcinoma], OV[Ovarian serous cystadenocarcinoma ], PAAD[Pancreatic adenocarcinoma], PRAD[Prostate adenocarcinoma], SKCM[Skin Cutaneous Melanoma], STAD[Stomach adenocarcinoma], THCA[Thyroid carcinoma], UCEC[Uterine Corpus Endometrial Carcinoma]

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Gene Expression for CA2

check002.gifGene Expression in Cancer Cell-lines (CCLE)
* CCLE gene expression data were extracted from CCLE_Expression_Entrez_2012-10-18.res: Gene-centric RMA-normalized mRNA expression data.

check002.gifDifferential Gene Expression in Primary Tumors (TCGA)
* Normalized gene expression data of RNASeqV2 was extracted from TCGA using R package TCGA-Assembler. The URLs of all public data files on TCGA DCC data server were gathered at Jan-05-2015. Only eight cancer types have enough normal control samples for differential expression analysis.
(t test, adjusted p<0.05 (using Benjamini-Hochberg FDR))
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check002.gifCNV vs Gene Expression Plot
* This plots show the correlation between CNV and gene expression.

: Open all plots for all cancer types


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Gene-Gene Network Information
check002.gifCo-Expressed gene's network Plot
* Co-Expression network figures were drawn using R package igraph. Only the top 20 genes with the highest correlations were shown.
Red circle: input gene, orange circle: cell metabolism gene, sky circle: other gene

: Open all plots for all cancer types

ADRB1,AQP3,BDNF,CA2,CHN2,DYNLT3,HIGD1A,
HTR1F,LACTB,MORN2,MXD1,PAEP,PSKH2,RLN2,
RPS27L,SERPINA1,TMEM164,TPRG1,TRH,UGT2B11,UGT2B15		ADCY1,ERICH3,CA2,CCDC74A,CHAD,CST11,KCNK18,
LINC00202-1,OR51F1,PABPC1L2B,PPP4R4,SCGB1D2,SERPINA10,SERPINA1,
SERPINA6,SNORA11D,SNORA77,SNORD22,SNORD89,TAS2R8,TSPAN16

ABCB11,BTNL3,BTNL8,C11orf86,CA2,CA4,CDKN2B-AS1,
CEACAM7,CLCA4,EDN3,GBA3,GPT,GUCA2A,GUCA2B,
MS4A12,OTOP2,PLAC8,SCNN1B,SLC25A34,SLC2A13,TMIGD1		ABHD5,ACER3,AP3S2,APOBEC3B,C12orf49,CYSTM1,CA2,
MICU2,ETHE1,ETNK1,FABP1,FUCA1,GDPD3,GHITM,
NRAS,PKIB,SHD,SRI,TST,UBE2A,UGDH
check002.gifCo-Expressed gene's Protein-protein interaction Network Plot
* Co-Expression network figures were drawn using R package igraph. Only the top 20 genes with the highest correlations were shown.
Red circle: input gene, orange circle: cell metabolism gene, sky circle: other gene

: Open all plots for all cancer types

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check002.gifInteracting Genes (from Pathway Commons)

: Open all interacting genes' information including KEGG pathway for all interacting genes from DAVID

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Pharmacological Information for CA2
check002.gifCross-referenced pharmacological DB IDs from Uniprot
DB CategoryDB NameDB's ID and Url link
ChemistryBindingDB P00918; -.
ChemistryChEMBL CHEMBL205; -.
Organism-specific databasesPharmGKB PA25989; -.
Organism-specific databasesCTD 760; -.

check002.gifDrug-Gene Interaction Network
* Gene Centered Interaction Network.
* Drug Centered Interaction Network.
DrugBank IDTarget NameDrug GroupsGeneric NameDrug Centered NetworkDrug Structure
DB00232carbonic anhydrase IIapprovedMethyclothiazide
DB00273carbonic anhydrase IIapproved; investigationalTopiramate
DB00311carbonic anhydrase IIapprovedEthoxzolamide
DB00436carbonic anhydrase IIapprovedBendroflumethiazide
DB00562carbonic anhydrase IIapprovedBenzthiazide
DB00606carbonic anhydrase IIapprovedCyclothiazide
DB00695carbonic anhydrase IIapprovedFurosemide
DB00703carbonic anhydrase IIapprovedMethazolamide
DB00774carbonic anhydrase IIapprovedHydroflumethiazide
DB00819carbonic anhydrase IIapprovedAcetazolamide
DB00869carbonic anhydrase IIapprovedDorzolamide
DB00880carbonic anhydrase IIapprovedChlorothiazide
DB00909carbonic anhydrase IIapproved; investigationalZonisamide
DB00999carbonic anhydrase IIapprovedHydrochlorothiazide
DB01021carbonic anhydrase IIapprovedTrichlormethiazide
DB01031carbonic anhydrase IIillicit; approvedEthinamate
DB01119carbonic anhydrase IIapprovedDiazoxide
DB01144carbonic anhydrase IIapprovedDichlorphenamide
DB01194carbonic anhydrase IIapprovedBrinzolamide
DB01325carbonic anhydrase IIapprovedQuinethazone
DB01671carbonic anhydrase IIexperimental4-(Hydroxymercury)Benzoic Acid
DB01748carbonic anhydrase IIexperimentalN-Benzyl-4-Sulfamoyl-Benzamide
DB01784carbonic anhydrase IIexperimental4-Flourobenzenesulfonamide
DB01942carbonic anhydrase IIexperimentalFormic Acid
DB01964carbonic anhydrase IIexperimentalAL5424
DB02069carbonic anhydrase IIexperimentalN-(2-Flouro-Benzyl)-4-Sulfamoyl-Benzamide
DB02087carbonic anhydrase IIexperimental3,5-Difluorobenzenesulfonamide
DB02220carbonic anhydrase IIexperimentalAl7089a
DB02221carbonic anhydrase IIexperimental4-(Aminosulfonyl)-N-[(2,4,6-Trifluorophenyl)Methyl]-Benzamide
DB02292carbonic anhydrase IIexperimental6-Oxo-8,9,10,11-Tetrahydro-7h-Cyclohepta[C][1]Benzopyran-3-O-Sulfamate
DB02429carbonic anhydrase IIexperimental4-(Aminosulfonyl)-N-[(4-Fluorophenyl)Methyl]-Benzamide
DB02479carbonic anhydrase IIexperimental(R)-N-(3-Indol-1-Yl-2-Methyl-Propyl)-4-Sulfamoyl-Benzamide
DB02535carbonic anhydrase IIexperimentalAminodi(Ethyloxy)Ethylaminocarbonylbenzenesulfonamide
DB02602carbonic anhydrase IIexperimentalAL7182
DB02610carbonic anhydrase IIexperimentalN-(2,3,4,5,6-Pentaflouro-Benzyl)-4-Sulfamoyl-Benzamide
DB02679carbonic anhydrase IIexperimentalCyanamide
DB02861carbonic anhydrase IIexperimental4-(Aminosulfonyl)-N-[(3,4,5-Trifluorophenyl)Methyl]-Benzamide
DB02866carbonic anhydrase IIexperimentalDansylamide
DB02894carbonic anhydrase IIexperimentalSulfamic Acid 2,3-O-(1-Methylethylidene)-4,5-O-Sulfonyl-Beta-Fructopyranose Ester
DB02986carbonic anhydrase IIexperimentalN-(2-Thienylmethyl)-2,5-Thiophenedisulfonamide
DB03039carbonic anhydrase IIexperimental4-(Aminosulfonyl)-N-[(2,5-Difluorophenyl)Methyl]-Benzamide
DB03221carbonic anhydrase IIexperimentalAL7099A
DB03262carbonic anhydrase IIexperimentalAl-6619, [2h-Thieno[3,2-E]-1,2-Thiazine-6-Sulfonamide,2-(3-Hydroxyphenyl)-3-(4-Morpholinyl)-, 1,1-Dioxide]
DB03270carbonic anhydrase IIexperimental2,6-Difluorobenzenesulfonamide
DB03294carbonic anhydrase IIexperimental1-Methyl-3-Oxo-1,3-Dihydro-Benzo[C]Isothiazole-5-Sulfonic Acid Amide
DB03333carbonic anhydrase IIexperimental(4-sulfamoyl-phenyl)-thiocarbamic acid O-(2-thiophen-3-yl-ethyl) ester
DB03385carbonic anhydrase IIexperimental4-Methylimidazole
DB03526carbonic anhydrase IIexperimentalAL5927
DB03594carbonic anhydrase IIexperimental1,2,4-Triazole
DB03596carbonic anhydrase IIexperimentalN-[2-(1h-Indol-5-Yl)-Butyl]-4-Sulfamoyl-Benzamide
DB03598carbonic anhydrase IIexperimentalAl-6629, [2h-Thieno[3,2-E]-1,2-Thiazine-6-Sulfonamide,2-(3-Methoxyphenyl)-3-(4-Morpholinyl)-, 1,1-Dioxide]
DB03674carbonic anhydrase IIexperimentalMethyl Mercury Ion
DB03697carbonic anhydrase IIexperimental4-Sulfonamide-[1-(4-Aminobutane)]Benzamide
DB03844carbonic anhydrase IIexperimentalN-(2,6-Diflouro-Benzyl)-4-Sulfamoyl-Benzamide
DB03877carbonic anhydrase IIexperimentalAL4623
DB03904carbonic anhydrase IIexperimentalUrea
DB03950carbonic anhydrase IIexperimental(S)-N-(3-Indol-1-Yl-2-Methyl-Propyl)-4-Sulfamoyl-Benzamide
DB03975carbonic anhydrase IIexperimentalMercuribenzoic Acid
DB04002carbonic anhydrase IIexperimental4-Sulfonamide-[4-(Thiomethylaminobutane)]Benzamide
DB04081carbonic anhydrase IIexperimental(4s-Trans)-4-(Methylamino)-5,6-Dihydro-6-Methyl-4h-Thieno(2,3-B)Thiopyran-2-Sulfonamide-7,7-Dioxide
DB04089carbonic anhydrase IIexperimentalAL5300
DB04180carbonic anhydrase IIexperimental4-(Aminosulfonyl)-N-[(2,4-Difluorophenyl)Methyl]-Benzamide
DB04203carbonic anhydrase IIexperimental3-Mercuri-4-Aminobenzenesulfonamide
DB04371carbonic anhydrase IIexperimentalAL6528
DB04394carbonic anhydrase IIexperimental3-Nitro-4-(2-Oxo-Pyrrolidin-1-Yl)-Benzenesulfonamide
DB04549carbonic anhydrase IIexperimental4-(Aminosulfonyl)-N-[(2,3,4-Trifluorophenyl)Methyl]-Benzamide
DB04600carbonic anhydrase IIexperimental4-[(3-BROMO-4-O-SULFAMOYLBENZYL)(4-CYANOPHENYL)AMINO]-4H-[1,2,4]-TRIAZOLE
DB04601carbonic anhydrase IIexperimental4-[(4-O-SULFAMOYLBENZYL)(4-CYANOPHENYL)AMINO]-4H-[1,2,4]-TRIAZOLE
DB04763carbonic anhydrase IIexperimental1-N-(4-SULFAMOYLPHENYL-ETHYL)-2,4,6-TRIMETHYLPYRIDINIUM
DB06891carbonic anhydrase IIexperimental5-{[(4-AMINO-3-CHLORO-5-FLUOROPHENYL)SULFONYL]AMINO}-1,3,4-THIADIAZOLE-2-SULFONAMIDE
DB06954carbonic anhydrase IIexperimental2-(cycloheptylmethyl)-1,1-dioxido-1-benzothiophen-6-yl sulfamate
DB07048carbonic anhydrase IIexperimentalN-[(2R)-5-(aminosulfonyl)-2,3-dihydro-1H-inden-2-yl]-2-propylpentanamide
DB07050carbonic anhydrase IIexperimental5-[(phenylsulfonyl)amino]-1,3,4-thiadiazole-2-sulfonamide
DB07363carbonic anhydrase IIexperimentalTHIOPHENE-2,5-DISULFONIC ACID 2-AMIDE-5-(4-METHYL-BENZYLAMIDE)
DB07467carbonic anhydrase IIexperimental4-chloro-N-[(2S)-2-methyl-2,3-dihydro-1H-indol-1-yl]-3-sulfamoylbenzamide
DB07476carbonic anhydrase IIexperimentalN-[4-(AMINOSULFONYL)PHENYL]-2-MERCAPTOBENZAMIDE
DB07596carbonic anhydrase IIexperimental(17beta)-17-(cyanomethyl)-2-methoxyestra-1(10),2,4-trien-3-yl sulfamate
DB07632carbonic anhydrase IIexperimental5-(2-chlorophenyl)-1,3,4-thiadiazole-2-sulfonamide
DB07710carbonic anhydrase IIexperimentalPHENYLALANYLAMINODI(ETHYLOXY)ETHYL BENZENESULFONAMIDEAMINOCARBONYLBENZENESULFONAMIDE
DB07742carbonic anhydrase IIexperimentalN-(2,3-DIFLUORO-BENZYL)-4-SULFAMOYL-BENZAMIDE
DB08046carbonic anhydrase IIexperimental2-chloro-5-[(1S)-1-hydroxy-3-oxo-2H-isoindol-1-yl]benzenesulfonamide
DB08083carbonic anhydrase IIexperimental2-(1,3-thiazol-4-yl)-1H-benzimidazole-5-sulfonamide
DB08155carbonic anhydrase IIexperimentalN-{2-[4-(AMINOSULFONYL)PHENYL]ETHYL}ACETAMIDE
DB08156carbonic anhydrase IIexperimental3-[4-(AMINOSULFONYL)PHENYL]PROPANOIC ACID
DB08157carbonic anhydrase IIexperimentalETHYL 3-[4-(AMINOSULFONYL)PHENYL]PROPANOATE
DB08165carbonic anhydrase IIexperimentalindane-5-sulfonamide
DB08202carbonic anhydrase IIexperimental4-({[(4-METHYLPIPERAZIN-1-YL)AMINO]CARBONOTHIOYL}AMINO)BENZENESULFONAMIDE
DB08301carbonic anhydrase IIexperimentalN-({[4-(AMINOSULFONYL)PHENYL]AMINO}CARBONYL)-4-METHYLBENZENESULFONAMIDE
DB08329carbonic anhydrase IIexperimentalSULTHIAME
DB08416carbonic anhydrase IIexperimental(9BETA,13ALPHA,14BETA,17ALPHA)-2-METHOXYESTRA-1,3,5(10)-TRIENE-3,17-DIYL DISULFAMATE
DB08418carbonic anhydrase IIexperimental(4aS,4bR,10bS,12aS)-12a-methyl-1,3-dioxo-2-(pyridin-3-ylmethyl)-1,2,3,4,4a,4b,5,6,10b,11,12,12a-dodecahydronaphtho[2,1-f]isoquinolin-8-yl sulfamate
DB08645carbonic anhydrase IIexperimental6-CHLORO-3-(DICHLOROMETHYL)-3,4-DIHYDRO-2H-1,2,4-BENZOTHIADIAZINE-7-SULFONAMIDE 1,1-DIOXIDE
DB08659carbonic anhydrase IIexperimental2-(hydrazinocarbonyl)-3-phenyl-1H-indole-5-sulfonamide
DB08765carbonic anhydrase IIexperimental6-HYDROXY-1,3-BENZOTHIAZOLE-2-SULFONAMIDE
DB08782carbonic anhydrase IIexperimental4-(2-AMINOETHYL)BENZENESULFONAMIDE
DB00259carbonic anhydrase IIapprovedSulfanilamide


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Cross referenced IDs for CA2
* We obtained these cross-references from Uniprot database. It covers 150 different DBs, 18 categories. http://www.uniprot.org/help/cross_references_section

: Open all cross reference information



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