Cancer Cell Metabolism Gene Database

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Bioinformatics and Systems Medicine Laboratory Bioinformatics and Systems Medicine Laboratory
Cross referenced IDs for 2475
* We obtained these cross-references from Uniprot database. It covers 150 different DBs, 18 categories. http://www.uniprot.org/help/cross_references_section
DB CategoryDB NameDB's ID and Url link
Genome annotation databasesEnsembl ENST00000361445; ENSP00000354558; ENSG00000198793.
Genome annotation databasesGeneID 2475; -.
Genome annotation databasesKEGG hsa:2475; -.
Genome annotation databasesUCSC uc001asd.3; human.
Sequence databasesCCDS CCDS127.1; -.
Sequence databasesEMBL L34075; AAA58486.1; -; mRNA.
Sequence databasesEMBL U88966; AAC39933.1; ALT_FRAME; mRNA.
Sequence databasesEMBL AB209995; BAE06077.1; ALT_INIT; mRNA.
Sequence databasesEMBL AL109811; CAI22105.1; -; Genomic_DNA.
Sequence databasesEMBL AL049653; CAI22105.1; JOINED; Genomic_DNA.
Sequence databasesEMBL AL391561; CAI22105.1; JOINED; Genomic_DNA.
Sequence databasesEMBL AL391561; CAI17228.1; -; Genomic_DNA.
Sequence databasesEMBL AL049653; CAI17228.1; JOINED; Genomic_DNA.
Sequence databasesEMBL AL109811; CAI17228.1; JOINED; Genomic_DNA.
Sequence databasesEMBL AL049653; CAI22145.1; -; Genomic_DNA.
Sequence databasesEMBL AL109811; CAI22145.1; JOINED; Genomic_DNA.
Sequence databasesEMBL AL391561; CAI22145.1; JOINED; Genomic_DNA.
Sequence databasesEMBL BC117166; AAI17167.1; -; mRNA.
Sequence databasesEMBL AJ300188; CAC15570.1; -; Genomic_DNA.
Sequence databasesEMBL L35478; AAC41713.1; -; mRNA.
Sequence databasesPIR S45340; S45340.
Sequence databasesRefSeq NP_004949.1; NM_004958.3.
Sequence databasesRefSeq XP_005263495.1; XM_005263438.1.
Sequence databasesUniGene Hs.338207; -.
Polymorphism databasesDMDM 1169735; -.
Gene expression databasesBgee P42345; -.
Gene expression databasesCleanEx HS_FRAP1; -.
Gene expression databasesExpressionAtlas P42345; baseline and differential.
Gene expression databasesGenevestigator P42345; -.
OntologiesGO GO:0005737; C:cytoplasm; IDA:UniProtKB.
OntologiesGO GO:0005829; C:cytosol; TAS:Reactome.
OntologiesGO GO:0012505; C:endomembrane system; IDA:UniProtKB.
OntologiesGO GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.
OntologiesGO GO:0005794; C:Golgi apparatus; IEA:UniProtKB-KW.
OntologiesGO GO:0005765; C:lysosomal membrane; IDA:UniProtKB.
OntologiesGO GO:0005764; C:lysosome; IDA:UniProtKB.
OntologiesGO GO:0016020; C:membrane; IDA:UniProtKB.
OntologiesGO GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-KW.
OntologiesGO GO:0005942; C:phosphatidylinositol 3-kinase complex; NAS:UniProtKB.
OntologiesGO GO:0016605; C:PML body; IEA:Ensembl.
OntologiesGO GO:0031931; C:TORC1 complex; IDA:UniProtKB.
OntologiesGO GO:0031932; C:TORC2 complex; IDA:UniProtKB.
OntologiesGO GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
OntologiesGO GO:0008144; F:drug binding; IEA:InterPro.
OntologiesGO GO:0016301; F:kinase activity; TAS:UniProtKB.
OntologiesGO GO:0051219; F:phosphoprotein binding; IPI:UniProtKB.
OntologiesGO GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
OntologiesGO GO:0043022; F:ribosome binding; IEA:Ensembl.
OntologiesGO GO:0001030; F:RNA polymerase III type 1 promoter DNA binding; IDA:UniProtKB.
OntologiesGO GO:0001031; F:RNA polymerase III type 2 promoter DNA binding; IDA:UniProtKB.
OntologiesGO GO:0001032; F:RNA polymerase III type 3 promoter DNA binding; IDA:UniProtKB.
OntologiesGO GO:0001156; F:TFIIIC-class transcription factor binding; IDA:UniProtKB.
OntologiesGO GO:0016049; P:cell growth; IDA:UniProtKB.
OntologiesGO GO:0071456; P:cellular response to hypoxia; ISS:UniProtKB.
OntologiesGO GO:0031669; P:cellular response to nutrient levels; ISS:UniProtKB.
OntologiesGO GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
OntologiesGO GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
OntologiesGO GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
OntologiesGO GO:0007281; P:germ cell development; IEA:Ensembl.
OntologiesGO GO:0040007; P:growth; NAS:UniProtKB.
OntologiesGO GO:0045087; P:innate immune response; TAS:Reactome.
OntologiesGO GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
OntologiesGO GO:0010507; P:negative regulation of autophagy; ISS:UniProtKB.
OntologiesGO GO:0045792; P:negative regulation of cell size; IEA:Ensembl.
OntologiesGO GO:0016242; P:negative regulation of macroautophagy; IEA:Ensembl.
OntologiesGO GO:0051534; P:negative regulation of NFAT protein import into nucleus; IEA:Ensembl.
OntologiesGO GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
OntologiesGO GO:0018105; P:peptidyl-serine phosphorylation; IMP:UniProtKB.
OntologiesGO GO:0018107; P:peptidyl-threonine phosphorylation; IEA:Ensembl.
OntologiesGO GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
OntologiesGO GO:0016310; P:phosphorylation; IDA:UniProtKB.
OntologiesGO GO:0030838; P:positive regulation of actin filament polymerization; IEA:Ensembl.
OntologiesGO GO:0001938; P:positive regulation of endothelial cell proliferation; IEA:Ensembl.
OntologiesGO GO:0010628; P:positive regulation of gene expression; IMP:UniProtKB.
OntologiesGO GO:0010592; P:positive regulation of lamellipodium assembly; IEA:Ensembl.
OntologiesGO GO:0046889; P:positive regulation of lipid biosynthetic process; IMP:UniProtKB.
OntologiesGO GO:0010831; P:positive regulation of myotube differentiation; IEA:Ensembl.
OntologiesGO GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IEA:Ensembl.
OntologiesGO GO:0051897; P:positive regulation of protein kinase B signaling; IEA:Ensembl.
OntologiesGO GO:0001934; P:positive regulation of protein phosphorylation; IDA:UniProtKB.
OntologiesGO GO:0051496; P:positive regulation of stress fiber assembly; IEA:Ensembl.
OntologiesGO GO:0045945; P:positive regulation of transcription from RNA polymerase III promoter; IMP:UniProtKB.
OntologiesGO GO:0045727; P:positive regulation of translation; IDA:UniProtKB.
OntologiesGO GO:0046777; P:protein autophosphorylation; IDA:MGI.
OntologiesGO GO:0030163; P:protein catabolic process; TAS:UniProtKB.
OntologiesGO GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
OntologiesGO GO:0032956; P:regulation of actin cytoskeleton organization; IMP:UniProtKB.
OntologiesGO GO:0043610; P:regulation of carbohydrate utilization; IEA:Ensembl.
OntologiesGO GO:0031998; P:regulation of fatty acid beta-oxidation; IEA:Ensembl.
OntologiesGO GO:0005979; P:regulation of glycogen biosynthetic process; IEA:Ensembl.
OntologiesGO GO:0045859; P:regulation of protein kinase activity; IEA:Ensembl.
OntologiesGO GO:0032314; P:regulation of Rac GTPase activity; IEA:Ensembl.
OntologiesGO GO:0032095; P:regulation of response to food; IEA:Ensembl.
OntologiesGO GO:0043200; P:response to amino acid; IDA:UniProtKB.
OntologiesGO GO:0007584; P:response to nutrient; NAS:UniProtKB.
OntologiesGO GO:0006950; P:response to stress; IMP:UniProtKB.
OntologiesGO GO:0031529; P:ruffle organization; IEA:Ensembl.
OntologiesGO GO:0007165; P:signal transduction; NAS:UniProtKB.
OntologiesGO GO:0031295; P:T cell costimulation; TAS:Reactome.
OntologiesGO GO:0031929; P:TOR signaling; IMP:UniProtKB.
Proteomic databasesMaxQB P42345; -.
Proteomic databasesPaxDb P42345; -.
Proteomic databasesPRIDE P42345; -.
Family and domain databasesGene3D 1.10.1070.11; -; 3.
Family and domain databasesGene3D 1.20.120.150; -; 1.
Family and domain databasesGene3D 1.25.10.10; -; 4.
Family and domain databasesGene3D 1.25.40.10; -; 2.
Family and domain databasesInterPro IPR011989; ARM-like.
Family and domain databasesInterPro IPR016024; ARM-type_fold.
Family and domain databasesInterPro IPR024585; DUF3385_TOR.
Family and domain databasesInterPro IPR003152; FATC.
Family and domain databasesInterPro IPR011009; Kinase-like_dom.
Family and domain databasesInterPro IPR000403; PI3/4_kinase_cat_dom.
Family and domain databasesInterPro IPR018936; PI3/4_kinase_CS.
Family and domain databasesInterPro IPR003151; PIK-rel_kinase_FAT.
Family and domain databasesInterPro IPR014009; PIK_FAT.
Family and domain databasesInterPro IPR009076; Rapamycin-bd_dom.
Family and domain databasesInterPro IPR011990; TPR-like_helical_dom.
Family and domain databasesPfam PF11865; DUF3385; 1.
Family and domain databasesPfam PF02259; FAT; 1.
Family and domain databasesPfam PF02260; FATC; 1.
Family and domain databasesPfam PF00454; PI3_PI4_kinase; 1.
Family and domain databasesPfam PF08771; Rapamycin_bind; 1.
Family and domain databasesPROSITE PS51189; FAT; 1.
Family and domain databasesPROSITE PS51190; FATC; 1.
Family and domain databasesPROSITE PS00915; PI3_4_KINASE_1; 1.
Family and domain databasesPROSITE PS00916; PI3_4_KINASE_2; 1.
Family and domain databasesPROSITE PS50290; PI3_4_KINASE_3; 1.
Family and domain databasesSMART SM00146; PI3Kc; 1.
Family and domain databasesSUPFAM SSF47212; SSF47212; 1.
Family and domain databasesSUPFAM SSF48371; SSF48371; 5.
Family and domain databasesSUPFAM SSF56112; SSF56112; 2.
PTM databasesPhosphoSite P42345; -.
Protein-protein interaction databasesBioGrid 108757; 110.
Protein-protein interaction databasesDIP DIP-790N; -.
Protein-protein interaction databasesIntAct P42345; 49.
Protein-protein interaction databasesMINT MINT-121301; -.
Protein-protein interaction databasesSTRING 9606.ENSP00000354558; -.
Enzyme and pathway databasesReactome REACT_147727; Constitutive PI3K/AKT Signaling in Cancer.
Enzyme and pathway databasesReactome REACT_19358; CD28 dependent PI3K/Akt signaling.
Enzyme and pathway databasesReactome REACT_200775; HSF1-dependent transactivation.
Enzyme and pathway databasesReactome REACT_228016; VEGFR2 mediated vascular permeability.
Enzyme and pathway databasesReactome REACT_6754; S6K1-mediated signalling.
Enzyme and pathway databasesReactome REACT_6836; Release of eIF4E.
Enzyme and pathway databasesReactome REACT_6838; mTOR signalling.
Enzyme and pathway databasesReactome REACT_75829; PIP3 activates AKT signaling.
Enzyme and pathway databasesSignaLink P42345; -.
3D structure databasesPDB 1AUE; X-ray; 2.33 A; A/B=2015-2114.
3D structure databasesPDB 1FAP; X-ray; 2.70 A; B=2018-2112.
3D structure databasesPDB 1NSG; X-ray; 2.20 A; B=2019-2112.
3D structure databasesPDB 2FAP; X-ray; 2.20 A; B=2019-2112.
3D structure databasesPDB 2GAQ; NMR; -; A=2015-2114.
3D structure databasesPDB 2NPU; NMR; -; A=2015-2114.
3D structure databasesPDB 2RSE; NMR; -; B=2019-2112.
3D structure databasesPDB 3FAP; X-ray; 1.85 A; B=2019-2112.
3D structure databasesPDB 4DRH; X-ray; 2.30 A; B/E=2025-2114.
3D structure databasesPDB 4DRI; X-ray; 1.45 A; B=2025-2114.
3D structure databasesPDB 4DRJ; X-ray; 1.80 A; B=2025-2114.
3D structure databasesPDB 4FAP; X-ray; 2.80 A; B=2019-2112.
3D structure databasesPDB 4JSN; X-ray; 3.20 A; A/B=1376-2549.
3D structure databasesPDB 4JSP; X-ray; 3.30 A; A/B=1376-2549.
3D structure databasesPDB 4JSV; X-ray; 3.50 A; A/B=1376-2549.
3D structure databasesPDB 4JSX; X-ray; 3.50 A; A/B=1376-2549.
3D structure databasesPDB 4JT5; X-ray; 3.45 A; A/B=1376-2549.
3D structure databasesPDB 4JT6; X-ray; 3.60 A; A/B=1376-2549.
3D structure databasesPDBsum 1AUE; -.
3D structure databasesPDBsum 1FAP; -.
3D structure databasesPDBsum 1NSG; -.
3D structure databasesPDBsum 2FAP; -.
3D structure databasesPDBsum 2GAQ; -.
3D structure databasesPDBsum 2NPU; -.
3D structure databasesPDBsum 2RSE; -.
3D structure databasesPDBsum 3FAP; -.
3D structure databasesPDBsum 4DRH; -.
3D structure databasesPDBsum 4DRI; -.
3D structure databasesPDBsum 4DRJ; -.
3D structure databasesPDBsum 4FAP; -.
3D structure databasesPDBsum 4JSN; -.
3D structure databasesPDBsum 4JSP; -.
3D structure databasesPDBsum 4JSV; -.
3D structure databasesPDBsum 4JSX; -.
3D structure databasesPDBsum 4JT5; -.
3D structure databasesPDBsum 4JT6; -.
3D structure databasesProteinModelPortal P42345; -.
3D structure databasesSMR P42345; 164-213, 430-463, 580-631, 696-895, 991-1082, 2025-2422, 2517-2549.
Phylogenomic databaseseggNOG COG5032; -.
Phylogenomic databasesGeneTree ENSGT00760000119382; -.
Phylogenomic databasesHOGENOM HOG000163215; -.
Phylogenomic databasesHOVERGEN HBG005744; -.
Phylogenomic databasesInParanoid P42345; -.
Phylogenomic databasesKO K07203; -.
Phylogenomic databasesOMA TYKQNIG; -.
Phylogenomic databasesPhylomeDB P42345; -.
Phylogenomic databasesTreeFam TF105134; -.
Organism-specific databasesCTD 2475; -.
Organism-specific databasesGeneCards GC01M011166; -.
Organism-specific databasesHGNC HGNC:3942; MTOR.
Organism-specific databasesHPA CAB005057; -.
Organism-specific databasesMIM 601231; gene.
Organism-specific databasesneXtProt NX_P42345; -.
Organism-specific databasesPharmGKB PA28360; -.
ChemistryBindingDB P42345; -.
ChemistryChEMBL CHEMBL2221341; -.
ChemistryDrugBank DB01590; Everolimus.
ChemistryDrugBank DB00337; Pimecrolimus.
ChemistryDrugBank DB00877; Sirolimus.
ChemistryDrugBank DB06287; Temsirolimus.
ChemistryGuidetoPHARMACOLOGY 2109; -.
OtherChiTaRS MTOR; human.
OtherEvolutionaryTrace P42345; -.
OtherGeneWiki Mammalian_target_of_rapamycin; -.
OtherGenomeRNAi 2475; -.
OtherNextBio 9805; -.
OtherPRO PR:P42345; -.



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