Cancer Cell Metabolism Gene Database

  Cancer Cell Metabolism Gene DB






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Bioinformatics and Systems Medicine Laboratory Bioinformatics and Systems Medicine Laboratory
Cross referenced IDs for 5566
* We obtained these cross-references from Uniprot database. It covers 150 different DBs, 18 categories.
DB CategoryDB NameDB's ID and Url link
Genome annotation databasesEnsembl ENST00000308677; ENSP00000309591; ENSG00000072062. [P17612-1]
Genome annotation databasesGeneID 5566; -.
Genome annotation databasesKEGG hsa:5566; -.
Genome annotation databasesUCSC uc002myb.3; human. [P17612-2]
Genome annotation databasesUCSC uc002myc.3; human. [P17612-1]
Sequence databasesCCDS CCDS12304.1; -. [P17612-1]
Sequence databasesEMBL X07767; CAA30597.1; -; mRNA.
Sequence databasesEMBL AK290147; BAF82836.1; -; mRNA.
Sequence databasesEMBL DQ667173; ABG25918.1; -; Genomic_DNA.
Sequence databasesEMBL CH471106; EAW84399.1; -; Genomic_DNA.
Sequence databasesEMBL BC039846; AAH39846.1; -; mRNA.
Sequence databasesEMBL BC108259; AAI08260.1; -; mRNA.
Sequence databasesEMBL AF208004; AAG35720.1; -; mRNA.
Sequence databasesEMBL AF239744; AAF76426.1; -; mRNA.
Sequence databasesEMBL AF224718; AAF75622.1; -; mRNA.
Sequence databasesPIR S01404; OKHU2C.
Sequence databasesRefSeq NP_002721.1; NM_002730.3. [P17612-1]
Sequence databasesRefSeq NP_997401.1; NM_207518.1.
Sequence databasesUniGene Hs.631630; -.
Polymorphism databasesDMDM 125205; -.
Gene expression databasesBgee P17612; -.
Gene expression databasesCleanEx HS_PRKACA; -.
Gene expression databasesExpressionAtlas P17612; baseline and differential.
Gene expression databasesGenevestigator P17612; -.
OntologiesGO GO:0031588; C:AMP-activated protein kinase complex; IDA:BHF-UCL.
OntologiesGO GO:0034704; C:calcium channel complex; TAS:BHF-UCL.
OntologiesGO GO:0005952; C:cAMP-dependent protein kinase complex; NAS:UniProtKB.
OntologiesGO GO:0005813; C:centrosome; IDA:UniProtKB.
OntologiesGO GO:0097546; C:ciliary base; IEA:Ensembl.
OntologiesGO GO:0005829; C:cytosol; TAS:Reactome.
OntologiesGO GO:0070062; C:extracellular vesicular exosome; IDA:UniProtKB.
OntologiesGO GO:0005739; C:mitochondrion; IEA:UniProtKB-KW.
OntologiesGO GO:0031514; C:motile cilium; IEA:UniProtKB-KW.
OntologiesGO GO:0031594; C:neuromuscular junction; IEA:Ensembl.
OntologiesGO GO:0005634; C:nucleus; IDA:UniProt.
OntologiesGO GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
OntologiesGO GO:0097225; C:sperm midpiece; IDA:UniProtKB.
OntologiesGO GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
OntologiesGO GO:0004691; F:cAMP-dependent protein kinase activity; IDA:BHF-UCL.
OntologiesGO GO:0034237; F:protein kinase A regulatory subunit binding; IPI:BHF-UCL.
OntologiesGO GO:0019901; F:protein kinase binding; IPI:BHF-UCL.
OntologiesGO GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IDA:MGI.
OntologiesGO GO:0031625; F:ubiquitin protein ligase binding; IDA:UniProtKB.
OntologiesGO GO:0007202; P:activation of phospholipase C activity; TAS:Reactome.
OntologiesGO GO:0034199; P:activation of protein kinase A activity; TAS:Reactome.
OntologiesGO GO:0007596; P:blood coagulation; TAS:Reactome.
OntologiesGO GO:0035584; P:calcium-mediated signaling using intracellular calcium source; TAS:BHF-UCL.
OntologiesGO GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
OntologiesGO GO:0086064; P:cell communication by electrical coupling involved in cardiac conduction; TAS:BHF-UCL.
OntologiesGO GO:0071872; P:cellular response to epinephrine stimulus; TAS:BHF-UCL.
OntologiesGO GO:0071377; P:cellular response to glucagon stimulus; TAS:Reactome.
OntologiesGO GO:0071333; P:cellular response to glucose stimulus; IDA:UniProtKB.
OntologiesGO GO:0071374; P:cellular response to parathyroid hormone stimulus; IEA:Ensembl.
OntologiesGO GO:0051480; P:cytosolic calcium ion homeostasis; TAS:BHF-UCL.
OntologiesGO GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
OntologiesGO GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
OntologiesGO GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
OntologiesGO GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
OntologiesGO GO:0006094; P:gluconeogenesis; TAS:Reactome.
OntologiesGO GO:0006006; P:glucose metabolic process; TAS:Reactome.
OntologiesGO GO:0045087; P:innate immune response; TAS:Reactome.
OntologiesGO GO:0035556; P:intracellular signal transduction; TAS:Reactome.
OntologiesGO GO:0001707; P:mesoderm formation; IEA:Ensembl.
OntologiesGO GO:0000278; P:mitotic cell cycle; TAS:Reactome.
OntologiesGO GO:1901621; P:negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning; IEA:Ensembl.
OntologiesGO GO:0001843; P:neural tube closure; IEA:Ensembl.
OntologiesGO GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
OntologiesGO GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.
OntologiesGO GO:0018107; P:peptidyl-threonine phosphorylation; IEA:Ensembl.
OntologiesGO GO:0071158; P:positive regulation of cell cycle arrest; ISS:UniProtKB.
OntologiesGO GO:0046827; P:positive regulation of protein export from nucleus; IEA:Ensembl.
OntologiesGO GO:0046777; P:protein autophosphorylation; IEA:Ensembl.
OntologiesGO GO:0006468; P:protein phosphorylation; NAS:UniProtKB.
OntologiesGO GO:0055117; P:regulation of cardiac muscle contraction; TAS:BHF-UCL.
OntologiesGO GO:0010881; P:regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion; TAS:BHF-UCL.
OntologiesGO GO:0002027; P:regulation of heart rate; TAS:BHF-UCL.
OntologiesGO GO:0050796; P:regulation of insulin secretion; TAS:Reactome.
OntologiesGO GO:0045667; P:regulation of osteoblast differentiation; IDA:UniProtKB.
OntologiesGO GO:0061136; P:regulation of proteasomal protein catabolic process; IDA:UniProtKB.
OntologiesGO GO:0043393; P:regulation of protein binding; TAS:BHF-UCL.
OntologiesGO GO:0070613; P:regulation of protein processing; IEA:Ensembl.
OntologiesGO GO:0060314; P:regulation of ryanodine-sensitive calcium-release channel activity; TAS:BHF-UCL.
OntologiesGO GO:0050804; P:regulation of synaptic transmission; IEA:Ensembl.
OntologiesGO GO:2000810; P:regulation of tight junction assembly; IDA:UniProtKB.
OntologiesGO GO:0007165; P:signal transduction; TAS:Reactome.
OntologiesGO GO:0044281; P:small molecule metabolic process; TAS:Reactome.
OntologiesGO GO:0048240; P:sperm capacitation; ISS:UniProtKB.
OntologiesGO GO:0055085; P:transmembrane transport; TAS:Reactome.
OntologiesGO GO:0019433; P:triglyceride catabolic process; TAS:Reactome.
OntologiesGO GO:0006833; P:water transport; TAS:Reactome.
Proteomic databasesMaxQB P17612; -.
Proteomic databasesPaxDb P17612; -.
Proteomic databasesPRIDE P17612; -.
Family and domain databasesInterPro IPR000961; AGC-kinase_C.
Family and domain databasesInterPro IPR011009; Kinase-like_dom.
Family and domain databasesInterPro IPR000719; Prot_kinase_dom.
Family and domain databasesInterPro IPR017441; Protein_kinase_ATP_BS.
Family and domain databasesInterPro IPR002290; Ser/Thr_dual-sp_kinase.
Family and domain databasesInterPro IPR008271; Ser/Thr_kinase_AS.
Family and domain databasesPfam PF00069; Pkinase; 1.
Family and domain databasesPROSITE PS51285; AGC_KINASE_CTER; 1.
Family and domain databasesPROSITE PS00107; PROTEIN_KINASE_ATP; 1.
Family and domain databasesPROSITE PS50011; PROTEIN_KINASE_DOM; 1.
Family and domain databasesPROSITE PS00108; PROTEIN_KINASE_ST; 1.
Family and domain databasesSMART SM00133; S_TK_X; 1.
Family and domain databasesSMART SM00220; S_TKc; 1.
Family and domain databasesSUPFAM SSF56112; SSF56112; 1.
PTM databasesPhosphoSite P17612; -.
Protein-protein interaction databasesBioGrid 111553; 114.
Protein-protein interaction databasesDIP DIP-33878N; -.
Protein-protein interaction databasesIntAct P17612; 58.
Protein-protein interaction databasesMINT MINT-95365; -.
Protein-protein interaction databasesSTRING 9606.ENSP00000309591; -.
Enzyme and pathway databasesBRENDA; 2681.
Enzyme and pathway databasesReactome REACT_1520; Gluconeogenesis.
Enzyme and pathway databasesReactome REACT_1525; PKA-mediated phosphorylation of key metabolic factors.
Enzyme and pathway databasesReactome REACT_15296; Recruitment of mitotic centrosome proteins and complexes.
Enzyme and pathway databasesReactome REACT_15334; DARPP-32 events.
Enzyme and pathway databasesReactome REACT_15364; Loss of Nlp from mitotic centrosomes.
Enzyme and pathway databasesReactome REACT_15451; Loss of proteins required for interphase microtubule organization from the centrosome.
Enzyme and pathway databasesReactome REACT_15497; PKA-mediated phosphorylation of CREB.
Enzyme and pathway databasesReactome REACT_15530; PKA activation.
Enzyme and pathway databasesReactome REACT_160315; Regulation of PLK1 Activity at G2/M Transition.
Enzyme and pathway databasesReactome REACT_18274; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion.
Enzyme and pathway databasesReactome REACT_18325; Regulation of insulin secretion.
Enzyme and pathway databasesReactome REACT_1946; PKA activation in glucagon signalling.
Enzyme and pathway databasesReactome REACT_20625; CREB phosphorylation through the activation of Adenylate Cyclase.
Enzyme and pathway databasesReactome REACT_206597; Degradation of GLI2 by the proteasome.
Enzyme and pathway databasesReactome REACT_228166; VEGFA-VEGFR2 Pathway.
Enzyme and pathway databasesReactome REACT_231645; GLI3 is processed to GLI3R by the proteasome.
Enzyme and pathway databasesReactome REACT_23837; Interleukin-3, 5 and GM-CSF signaling.
Enzyme and pathway databasesReactome REACT_23898; Rap1 signalling.
Enzyme and pathway databasesReactome REACT_24023; Vasopressin regulates renal water homeostasis via Aquaporins.
Enzyme and pathway databasesReactome REACT_24970; Factors involved in megakaryocyte development and platelet production.
Enzyme and pathway databasesReactome REACT_267605; Degradation of GLI1 by the proteasome.
Enzyme and pathway databasesReactome REACT_267634; Hedgehog 'off' state.
Enzyme and pathway databasesReactome REACT_494; Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis.
Enzyme and pathway databasesSignaLink P17612; -.
3D structure databasesPDB 2GU8; X-ray; 2.20 A; A=15-351.
3D structure databasesPDB 3AGL; X-ray; 2.10 A; A/B=1-351.
3D structure databasesPDB 3AGM; X-ray; 2.00 A; A=1-351.
3D structure databasesPDB 3AMA; X-ray; 1.75 A; A=1-351.
3D structure databasesPDB 3AMB; X-ray; 2.25 A; A=1-351.
3D structure databasesPDB 3L9L; X-ray; 2.00 A; A/B=1-351.
3D structure databasesPDB 3L9M; X-ray; 1.90 A; A/B=1-351.
3D structure databasesPDB 3L9N; X-ray; 2.00 A; A=1-351.
3D structure databasesPDB 3MVJ; X-ray; 2.49 A; A/B/E=1-351.
3D structure databasesPDB 3NX8; X-ray; 2.00 A; A=1-351.
3D structure databasesPDB 3OOG; X-ray; 2.00 A; A=1-351.
3D structure databasesPDB 3OVV; X-ray; 1.58 A; A=1-351.
3D structure databasesPDB 3OWP; X-ray; 1.88 A; A=1-351.
3D structure databasesPDB 3OXT; X-ray; 2.20 A; A=1-351.
3D structure databasesPDB 3P0M; X-ray; 2.03 A; A=1-351.
3D structure databasesPDB 3POO; X-ray; 1.60 A; A=1-351.
3D structure databasesPDB 3VQH; X-ray; 1.95 A; A=1-351.
3D structure databasesPDB 4AE6; X-ray; 2.10 A; A/B=16-351.
3D structure databasesPDB 4AE9; X-ray; 2.30 A; A/B=16-351.
3D structure databasesPDBsum 2GU8; -.
3D structure databasesPDBsum 3AGL; -.
3D structure databasesPDBsum 3AGM; -.
3D structure databasesPDBsum 3AMA; -.
3D structure databasesPDBsum 3AMB; -.
3D structure databasesPDBsum 3L9L; -.
3D structure databasesPDBsum 3L9M; -.
3D structure databasesPDBsum 3L9N; -.
3D structure databasesPDBsum 3MVJ; -.
3D structure databasesPDBsum 3NX8; -.
3D structure databasesPDBsum 3OOG; -.
3D structure databasesPDBsum 3OVV; -.
3D structure databasesPDBsum 3OWP; -.
3D structure databasesPDBsum 3OXT; -.
3D structure databasesPDBsum 3P0M; -.
3D structure databasesPDBsum 3POO; -.
3D structure databasesPDBsum 3VQH; -.
3D structure databasesPDBsum 4AE6; -.
3D structure databasesPDBsum 4AE9; -.
3D structure databasesProteinModelPortal P17612; -.
3D structure databasesSMR P17612; 15-351.
Protocols and materials databasesDNASU 5566; -.
Phylogenomic databaseseggNOG COG0515; -.
Phylogenomic databasesGeneTree ENSGT00770000120454; -.
Phylogenomic databasesHOGENOM HOG000233033; -.
Phylogenomic databasesHOVERGEN HBG108317; -.
Phylogenomic databasesInParanoid P17612; -.
Phylogenomic databasesKO K04345; -.
Phylogenomic databasesOMA GQHFAMK; -.
Phylogenomic databasesOrthoDB EOG7VX8WD; -.
Phylogenomic databasesPhylomeDB P17612; -.
Phylogenomic databasesTreeFam TF313399; -.
Organism-specific databasesCTD 5566; -.
Organism-specific databasesGeneCards GC19M014202; -.
Organism-specific databasesHGNC HGNC:9380; PRKACA.
Organism-specific databasesHPA CAB010361; -.
Organism-specific databasesMIM 601639; gene.
Organism-specific databasesMIM 615830; phenotype.
Organism-specific databasesneXtProt NX_P17612; -.
Organism-specific databasesOrphanet 401920; Fibrolamellar hepatocellular carcinoma.
Organism-specific databasesPharmGKB PA33748; -.
ChemistryBindingDB P17612; -.
ChemistryChEMBL CHEMBL2094138; -.
ChemistryGuidetoPHARMACOLOGY 1476; -.
OtherChiTaRS PRKACA; human.
OtherEvolutionaryTrace P17612; -.
OtherGeneWiki PRKACA; -.
OtherGenomeRNAi 5566; -.
OtherNextBio 21564; -.
OtherPRO PR:P17612; -.

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