Cancer Cell Metabolism Gene Database

  Cancer Cell Metabolism Gene DB

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Bioinformatics and Systems Medicine Laboratory Bioinformatics and Systems Medicine Laboratory
Cross referenced IDs for 5578
* We obtained these cross-references from Uniprot database. It covers 150 different DBs, 18 categories. http://www.uniprot.org/help/cross_references_section
DB CategoryDB NameDB's ID and Url link
Genome annotation databasesEnsembl ENST00000413366; ENSP00000408695; ENSG00000154229.
Genome annotation databasesGeneID 5578; -.
Genome annotation databasesKEGG hsa:5578; -.
Genome annotation databasesUCSC uc002jfo.1; human.
Sequence databasesCCDS CCDS11664.1; -.
Sequence databasesEMBL X52479; CAA36718.1; -; mRNA.
Sequence databasesEMBL AB451258; BAG70072.1; -; mRNA.
Sequence databasesEMBL AB451383; BAG70197.1; -; mRNA.
Sequence databasesEMBL AC005918; -; NOT_ANNOTATED_CDS; Genomic_DNA.
Sequence databasesEMBL AC005988; -; NOT_ANNOTATED_CDS; Genomic_DNA.
Sequence databasesEMBL AC006263; -; NOT_ANNOTATED_CDS; Genomic_DNA.
Sequence databasesEMBL AC006947; -; NOT_ANNOTATED_CDS; Genomic_DNA.
Sequence databasesEMBL AC009452; -; NOT_ANNOTATED_CDS; Genomic_DNA.
Sequence databasesEMBL AC060796; -; NOT_ANNOTATED_CDS; Genomic_DNA.
Sequence databasesEMBL CH471099; EAW89014.1; -; Genomic_DNA.
Sequence databasesEMBL BC109273; AAI09274.1; -; mRNA.
Sequence databasesEMBL BC109274; AAI09275.1; -; mRNA.
Sequence databasesEMBL M22199; AAA60098.1; -; mRNA.
Sequence databasesEMBL AF395829; AAK84184.1; -; Genomic_DNA.
Sequence databasesPIR S09496; KIHUCA.
Sequence databasesRefSeq NP_002728.1; NM_002737.2.
Sequence databasesUniGene Hs.531704; -.
Sequence databasesUniGene Hs.708867; -.
Polymorphism databasesDMDM 317373571; -.
Gene expression databasesBgee P17252; -.
Gene expression databasesCleanEx HS_PRKACA; -.
Gene expression databasesCleanEx HS_PRKCA; -.
Gene expression databasesExpressionAtlas P17252; baseline and differential.
Gene expression databasesGenevestigator P17252; -.
OntologiesGO GO:0045177; C:apical part of cell; IEA:Ensembl.
OntologiesGO GO:0005737; C:cytoplasm; IDA:UniProtKB.
OntologiesGO GO:0005829; C:cytosol; IDA:UniProtKB.
OntologiesGO GO:0030425; C:dendrite; IEA:Ensembl.
OntologiesGO GO:0005783; C:endoplasmic reticulum; IDA:BHF-UCL.
OntologiesGO GO:0070062; C:extracellular vesicular exosome; IDA:UniProt.
OntologiesGO GO:0005739; C:mitochondrion; IDA:UniProt.
OntologiesGO GO:0043025; C:neuronal cell body; IEA:Ensembl.
OntologiesGO GO:0005654; C:nucleoplasm; TAS:Reactome.
OntologiesGO GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.
OntologiesGO GO:0001750; C:photoreceptor outer segment; IEA:Ensembl.
OntologiesGO GO:0005886; C:plasma membrane; IDA:UniProtKB.
OntologiesGO GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
OntologiesGO GO:0004698; F:calcium-dependent protein kinase C activity; IEA:Ensembl.
OntologiesGO GO:0019899; F:enzyme binding; IDA:BHF-UCL.
OntologiesGO GO:0035403; F:histone kinase activity (H3-T6 specific); IDA:UniProtKB.
OntologiesGO GO:0004672; F:protein kinase activity; IDA:UniProtKB.
OntologiesGO GO:0004697; F:protein kinase C activity; ISS:BHF-UCL.
OntologiesGO GO:0008270; F:zinc ion binding; IEA:InterPro.
OntologiesGO GO:0007190; P:activation of adenylate cyclase activity; ISS:BHF-UCL.
OntologiesGO GO:0007202; P:activation of phospholipase C activity; TAS:Reactome.
OntologiesGO GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
OntologiesGO GO:0097190; P:apoptotic signaling pathway; TAS:ProtInc.
OntologiesGO GO:0007596; P:blood coagulation; TAS:Reactome.
OntologiesGO GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
OntologiesGO GO:0006874; P:cellular calcium ion homeostasis; IEA:Ensembl.
OntologiesGO GO:0071322; P:cellular response to carbohydrate stimulus; IEA:Ensembl.
OntologiesGO GO:0002062; P:chondrocyte differentiation; IEA:Ensembl.
OntologiesGO GO:0002159; P:desmosome assembly; IMP:BHF-UCL.
OntologiesGO GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
OntologiesGO GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
OntologiesGO GO:0030198; P:extracellular matrix organization; TAS:Reactome.
OntologiesGO GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
OntologiesGO GO:0010467; P:gene expression; TAS:Reactome.
OntologiesGO GO:0035408; P:histone H3-T6 phosphorylation; IDA:UniProtKB.
OntologiesGO GO:0000188; P:inactivation of MAPK activity; IEA:Ensembl.
OntologiesGO GO:0050930; P:induction of positive chemotaxis; IEA:Ensembl.
OntologiesGO GO:0045087; P:innate immune response; TAS:Reactome.
OntologiesGO GO:0097193; P:intrinsic apoptotic signaling pathway; IEA:Ensembl.
OntologiesGO GO:0016071; P:mRNA metabolic process; TAS:Reactome.
OntologiesGO GO:0007194; P:negative regulation of adenylate cyclase activity; ISS:BHF-UCL.
OntologiesGO GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
OntologiesGO GO:0034351; P:negative regulation of glial cell apoptotic process; IMP:UniProtKB.
OntologiesGO GO:0046325; P:negative regulation of glucose import; IEA:Ensembl.
OntologiesGO GO:0046627; P:negative regulation of insulin receptor signaling pathway; IEA:Ensembl.
OntologiesGO GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
OntologiesGO GO:0030593; P:neutrophil chemotaxis; IEA:Ensembl.
OntologiesGO GO:0036289; P:peptidyl-serine autophosphorylation; IEA:Ensembl.
OntologiesGO GO:0007603; P:phototransduction, visible light; TAS:Reactome.
OntologiesGO GO:0030168; P:platelet activation; TAS:Reactome.
OntologiesGO GO:0045766; P:positive regulation of angiogenesis; IMP:UniProtKB.
OntologiesGO GO:0043536; P:positive regulation of blood vessel endothelial cell migration; IDA:DFLAT.
OntologiesGO GO:0010613; P:positive regulation of cardiac muscle hypertrophy; ISS:UniProtKB.
OntologiesGO GO:0045785; P:positive regulation of cell adhesion; IMP:UniProtKB.
OntologiesGO GO:0030335; P:positive regulation of cell migration; IMP:UniProtKB.
OntologiesGO GO:2000707; P:positive regulation of dense core granule biogenesis; ISS:UniProtKB.
OntologiesGO GO:0010595; P:positive regulation of endothelial cell migration; IMP:UniProtKB.
OntologiesGO GO:0001938; P:positive regulation of endothelial cell proliferation; IMP:UniProtKB.
OntologiesGO GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.
OntologiesGO GO:0050729; P:positive regulation of inflammatory response; IEA:Ensembl.
OntologiesGO GO:0031666; P:positive regulation of lipopolysaccharide-mediated signaling pathway; IMP:UniProtKB.
OntologiesGO GO:0045651; P:positive regulation of macrophage differentiation; ISS:UniProtKB.
OntologiesGO GO:0045931; P:positive regulation of mitotic cell cycle; IMP:UniProtKB.
OntologiesGO GO:0001934; P:positive regulation of protein phosphorylation; IEA:Ensembl.
OntologiesGO GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
OntologiesGO GO:0050796; P:regulation of insulin secretion; TAS:Reactome.
OntologiesGO GO:0006937; P:regulation of muscle contraction; IEA:Ensembl.
OntologiesGO GO:0050730; P:regulation of peptidyl-tyrosine phosphorylation; IEA:Ensembl.
OntologiesGO GO:0090330; P:regulation of platelet aggregation; IDA:UniProtKB.
OntologiesGO GO:0022400; P:regulation of rhodopsin mediated signaling pathway; TAS:Reactome.
OntologiesGO GO:0002026; P:regulation of the force of heart contraction; IEA:Ensembl.
OntologiesGO GO:0070555; P:response to interleukin-1; IMP:BHF-UCL.
OntologiesGO GO:0016056; P:rhodopsin mediated signaling pathway; TAS:Reactome.
OntologiesGO GO:0016070; P:RNA metabolic process; TAS:Reactome.
OntologiesGO GO:0007165; P:signal transduction; TAS:Reactome.
OntologiesGO GO:0044281; P:small molecule metabolic process; TAS:Reactome.
OntologiesGO GO:0007268; P:synaptic transmission; TAS:Reactome.
Proteomic databasesMaxQB P17252; -.
Proteomic databasesPaxDb P17252; -.
Proteomic databasesPRIDE P17252; -.
Family and domain databasesGene3D 2.60.40.150; -; 1.
Family and domain databasesInterPro IPR000961; AGC-kinase_C.
Family and domain databasesInterPro IPR000008; C2_dom.
Family and domain databasesInterPro IPR020454; DAG/PE-bd.
Family and domain databasesInterPro IPR011009; Kinase-like_dom.
Family and domain databasesInterPro IPR002219; PE/DAG-bd.
Family and domain databasesInterPro IPR017892; Pkinase_C.
Family and domain databasesInterPro IPR000719; Prot_kinase_dom.
Family and domain databasesInterPro IPR017441; Protein_kinase_ATP_BS.
Family and domain databasesInterPro IPR014375; Protein_kinase_C_a/b/g.
Family and domain databasesInterPro IPR002290; Ser/Thr_dual-sp_kinase.
Family and domain databasesInterPro IPR008271; Ser/Thr_kinase_AS.
Family and domain databasesPfam PF00130; C1_1; 2.
Family and domain databasesPfam PF00168; C2; 1.
Family and domain databasesPfam PF00069; Pkinase; 1.
Family and domain databasesPfam PF00433; Pkinase_C; 1.
Family and domain databasesPIRSF PIRSF000550; PKC_alpha; 1.
Family and domain databasesPRINTS PR00360; C2DOMAIN.
Family and domain databasesPRINTS PR00008; DAGPEDOMAIN.
Family and domain databasesPROSITE PS51285; AGC_KINASE_CTER; 1.
Family and domain databasesPROSITE PS50004; C2; 1.
Family and domain databasesPROSITE PS00107; PROTEIN_KINASE_ATP; 1.
Family and domain databasesPROSITE PS50011; PROTEIN_KINASE_DOM; 1.
Family and domain databasesPROSITE PS00108; PROTEIN_KINASE_ST; 1.
Family and domain databasesPROSITE PS00479; ZF_DAG_PE_1; 2.
Family and domain databasesPROSITE PS50081; ZF_DAG_PE_2; 2.
Family and domain databasesSMART SM00109; C1; 2.
Family and domain databasesSMART SM00239; C2; 1.
Family and domain databasesSMART SM00133; S_TK_X; 1.
Family and domain databasesSMART SM00220; S_TKc; 1.
Family and domain databasesSUPFAM SSF49562; SSF49562; 1.
Family and domain databasesSUPFAM SSF56112; SSF56112; 1.
PTM databasesPhosphoSite P17252; -.
Protein-protein interaction databasesBioGrid 111564; 112.
Protein-protein interaction databasesDIP DIP-531N; -.
Protein-protein interaction databasesIntAct P17252; 27.
Protein-protein interaction databasesMINT MINT-140812; -.
Protein-protein interaction databasesSTRING 9606.ENSP00000284384; -.
Enzyme and pathway databasesBRENDA 2.7.11.13; 2681.
Enzyme and pathway databasesReactome REACT_111040; Signaling by SCF-KIT.
Enzyme and pathway databasesReactome REACT_111225; Regulation of KIT signaling.
Enzyme and pathway databasesReactome REACT_1178; Disinhibition of SNARE formation.
Enzyme and pathway databasesReactome REACT_121096; EGFR Transactivation by Gastrin.
Enzyme and pathway databasesReactome REACT_1280; Response to elevated platelet cytosolic Ca2+.
Enzyme and pathway databasesReactome REACT_163919; Inactivation, recovery and regulation of the phototransduction cascade.
Enzyme and pathway databasesReactome REACT_163942; Syndecan interactions.
Enzyme and pathway databasesReactome REACT_172599; WNT5A-dependent internalization of FZD4.
Enzyme and pathway databasesReactome REACT_172761; Ca2+ pathway.
Enzyme and pathway databasesReactome REACT_18405; Acetylcholine regulates insulin secretion.
Enzyme and pathway databasesReactome REACT_18422; Trafficking of GluR2-containing AMPA receptors.
Enzyme and pathway databasesReactome REACT_19333; G alpha (z) signalling events.
Enzyme and pathway databasesReactome REACT_200828; Depolymerisation of the Nuclear Lamina.
Enzyme and pathway databasesReactome REACT_228024; VEGFR2 mediated cell proliferation.
Enzyme and pathway databasesReactome REACT_25218; HuR stabilizes mRNA.
Enzyme and pathway databasesReactome REACT_9000; Calmodulin induced events.
Enzyme and pathway databasesSignaLink P17252; -.
3D structure databasesPDB 2ELI; NMR; -; A=93-169.
3D structure databasesPDB 3IW4; X-ray; 2.80 A; A/B/C=320-672.
3D structure databasesPDB 4DNL; X-ray; 1.90 A; A=155-293.
3D structure databasesPDBsum 2ELI; -.
3D structure databasesPDBsum 3IW4; -.
3D structure databasesPDBsum 4DNL; -.
3D structure databasesProteinModelPortal P17252; -.
3D structure databasesSMR P17252; 37-670.
Protocols and materials databasesDNASU 5578; -.
Phylogenomic databaseseggNOG COG0515; -.
Phylogenomic databasesGeneTree ENSGT00770000120449; -.
Phylogenomic databasesHOGENOM HOG000233022; -.
Phylogenomic databasesHOVERGEN HBG108317; -.
Phylogenomic databasesInParanoid P17252; -.
Phylogenomic databasesKO K02677; -.
Phylogenomic databasesOMA PQFVHPL; -.
Phylogenomic databasesOrthoDB EOG77M8QM; -.
Phylogenomic databasesPhylomeDB P17252; -.
Phylogenomic databasesTreeFam TF351133; -.
Organism-specific databasesCTD 5578; -.
Organism-specific databasesGeneCards GC17P064298; -.
Organism-specific databasesHGNC HGNC:9393; PRKCA.
Organism-specific databasesHPA CAB003844; -.
Organism-specific databasesHPA CAB016290; -.
Organism-specific databasesHPA HPA006563; -.
Organism-specific databasesHPA HPA006564; -.
Organism-specific databasesMIM 176960; gene.
Organism-specific databasesneXtProt NX_P17252; -.
Organism-specific databasesPharmGKB PA33759; -.
ChemistryBindingDB P17252; -.
ChemistryChEMBL CHEMBL2096620; -.
ChemistryDrugBank DB05013; Ingenol Mebutate.
ChemistryDrugBank DB00144; Phosphatidylserine.
ChemistryDrugBank DB00675; Tamoxifen.
ChemistryDrugBank DB00163; Vitamin E.
ChemistryGuidetoPHARMACOLOGY 1482; -.
OtherChiTaRS PRKCA; human.
OtherEvolutionaryTrace P17252; -.
OtherGeneWiki PKC_alpha; -.
OtherGenomeRNAi 5578; -.
OtherNextBio 21628; -.
OtherPMAP-CutDB P17252; -.
OtherPRO PR:P17252; -.



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