Cancer Cell Metabolism Gene Database

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Bioinformatics and Systems Medicine Laboratory Bioinformatics and Systems Medicine Laboratory
Cross referenced IDs for 7298
* We obtained these cross-references from Uniprot database. It covers 150 different DBs, 18 categories. http://www.uniprot.org/help/cross_references_section
DB CategoryDB NameDB's ID and Url link
Genome annotation databasesEnsembl ENST00000323224; ENSP00000314727; ENSG00000176890. [P04818-2]
Genome annotation databasesEnsembl ENST00000323250; ENSP00000314902; ENSG00000176890. [P04818-3]
Genome annotation databasesEnsembl ENST00000323274; ENSP00000315644; ENSG00000176890. [P04818-1]
Genome annotation databasesGeneID 7298; -.
Genome annotation databasesKEGG hsa:7298; -.
Genome annotation databasesUCSC uc010dka.1; human. [P04818-1]
Genome annotation databasesUCSC uc010dkb.1; human.
Genome annotation databasesUCSC uc010dkc.1; human.
Sequence databasesCCDS CCDS11821.1; -. [P04818-1]
Sequence databasesEMBL X02308; CAA26178.1; -; mRNA.
Sequence databasesEMBL D00596; BAA00472.1; -; Genomic_DNA.
Sequence databasesEMBL AB077207; BAB83676.1; -; mRNA.
Sequence databasesEMBL AB077208; BAB83677.1; -; mRNA.
Sequence databasesEMBL AB062290; BAB93473.1; -; mRNA.
Sequence databasesEMBL AP001178; -; NOT_ANNOTATED_CDS; Genomic_DNA.
Sequence databasesEMBL CH471113; EAX01716.1; -; Genomic_DNA.
Sequence databasesEMBL CH471113; EAX01720.1; -; Genomic_DNA.
Sequence databasesEMBL BC002567; AAH02567.1; -; mRNA.
Sequence databasesEMBL BC013919; AAH13919.1; -; mRNA.
Sequence databasesEMBL BC083512; AAH83512.1; -; mRNA.
Sequence databasesEMBL D00517; BAA00404.1; -; Genomic_DNA.
Sequence databasesPIR A23047; YXHUT.
Sequence databasesRefSeq NP_001062.1; NM_001071.2. [P04818-1]
Sequence databasesUniGene Hs.369762; -.
Polymorphism databasesDMDM 136611; -.
Gene expression databasesBgee P04818; -.
Gene expression databasesCleanEx HS_TYMS; -.
Gene expression databasesExpressionAtlas P04818; baseline and differential.
Gene expression databasesGenevestigator P04818; -.
OntologiesGO GO:0005737; C:cytoplasm; IDA:UniProtKB.
OntologiesGO GO:0005829; C:cytosol; TAS:Reactome.
OntologiesGO GO:0005743; C:mitochondrial inner membrane; IDA:UniProtKB.
OntologiesGO GO:0005759; C:mitochondrial matrix; IDA:UniProtKB.
OntologiesGO GO:0005739; C:mitochondrion; IDA:UniProtKB.
OntologiesGO GO:0005730; C:nucleolus; IEA:Ensembl.
OntologiesGO GO:0005654; C:nucleoplasm; TAS:Reactome.
OntologiesGO GO:0005634; C:nucleus; IDA:UniProtKB.
OntologiesGO GO:0048037; F:cofactor binding; IEA:Ensembl.
OntologiesGO GO:0008144; F:drug binding; IEA:Ensembl.
OntologiesGO GO:0005542; F:folic acid binding; IEA:Ensembl.
OntologiesGO GO:0003729; F:mRNA binding; IEA:Ensembl.
OntologiesGO GO:0000166; F:nucleotide binding; IEA:Ensembl.
OntologiesGO GO:0004799; F:thymidylate synthase activity; TAS:Reactome.
OntologiesGO GO:0007568; P:aging; IEA:Ensembl.
OntologiesGO GO:0051216; P:cartilage development; IEA:Ensembl.
OntologiesGO GO:0007623; P:circadian rhythm; IEA:Ensembl.
OntologiesGO GO:0009157; P:deoxyribonucleoside monophosphate biosynthetic process; TAS:ProtInc.
OntologiesGO GO:0048589; P:developmental growth; IEA:Ensembl.
OntologiesGO GO:0006231; P:dTMP biosynthetic process; IEA:Ensembl.
OntologiesGO GO:0006235; P:dTTP biosynthetic process; IEA:UniProtKB-UniPathway.
OntologiesGO GO:0046078; P:dUMP metabolic process; IEA:Ensembl.
OntologiesGO GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
OntologiesGO GO:0019088; P:immortalization of host cell by virus; IEA:Ensembl.
OntologiesGO GO:0060574; P:intestinal epithelial cell maturation; IEA:Ensembl.
OntologiesGO GO:0000278; P:mitotic cell cycle; TAS:Reactome.
OntologiesGO GO:0006139; P:nucleobase-containing compound metabolic process; TAS:ProtInc.
OntologiesGO GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
OntologiesGO GO:0031100; P:organ regeneration; IEA:Ensembl.
OntologiesGO GO:0005976; P:polysaccharide metabolic process; IEA:Ensembl.
OntologiesGO GO:0006206; P:pyrimidine nucleobase metabolic process; TAS:Reactome.
OntologiesGO GO:0046134; P:pyrimidine nucleoside biosynthetic process; TAS:Reactome.
OntologiesGO GO:0000083; P:regulation of transcription involved in G1/S transition of mitotic cell cycle; TAS:Reactome.
OntologiesGO GO:0034097; P:response to cytokine; IEA:Ensembl.
OntologiesGO GO:0042493; P:response to drug; IEA:Ensembl.
OntologiesGO GO:0045471; P:response to ethanol; IEA:Ensembl.
OntologiesGO GO:0051593; P:response to folic acid; IEA:Ensembl.
OntologiesGO GO:0051384; P:response to glucocorticoid; IEA:Ensembl.
OntologiesGO GO:0046683; P:response to organophosphorus; IEP:UniProtKB.
OntologiesGO GO:0032570; P:response to progesterone; IEA:Ensembl.
OntologiesGO GO:0009636; P:response to toxic substance; IEA:Ensembl.
OntologiesGO GO:0033189; P:response to vitamin A; IEA:Ensembl.
OntologiesGO GO:0044281; P:small molecule metabolic process; TAS:Reactome.
OntologiesGO GO:0046653; P:tetrahydrofolate metabolic process; IEA:Ensembl.
OntologiesGO GO:0019860; P:uracil metabolic process; IEA:Ensembl.
Proteomic databasesMaxQB P04818; -.
Proteomic databasesPaxDb P04818; -.
Proteomic databasesPRIDE P04818; -.
Family and domain databasesGene3D 3.30.572.10; -; 1.
Family and domain databasesHAMAP MF_00008; Thymidy_synth_bact; 1.
Family and domain databasesInterPro IPR023451; Thymidate_synth/dCMP_Mease.
Family and domain databasesInterPro IPR000398; Thymidylate_synthase.
Family and domain databasesInterPro IPR020940; Thymidylate_synthase_AS.
Family and domain databasesPfam PF00303; Thymidylat_synt; 1.
Family and domain databasesPRINTS PR00108; THYMDSNTHASE.
Family and domain databasesPROSITE PS00091; THYMIDYLATE_SYNTHASE; 1.
Family and domain databasesSUPFAM SSF55831; SSF55831; 1.
Family and domain databasesTIGRFAMs TIGR03284; thym_sym; 1.
PTM databasesPhosphoSite P04818; -.
Protein-protein interaction databasesBioGrid 113149; 39.
Protein-protein interaction databasesIntAct P04818; 2.
Protein-protein interaction databasesMINT MINT-2800458; -.
Protein-protein interaction databasesSTRING 9606.ENSP00000315644; -.
Enzyme and pathway databasesBioCyc MetaCyc:HS11096-MONOMER; -.
Enzyme and pathway databasesReactome REACT_21376; Pyrimidine biosynthesis.
Enzyme and pathway databasesReactome REACT_471; E2F mediated regulation of DNA replication.
Enzyme and pathway databasesReactome REACT_683; G1/S-Specific Transcription.
Enzyme and pathway databasesSABIO-RK P04818; -.
Enzyme and pathway databasesUniPathway UPA00575; -.
3D structure databasesDisProt DP00073; -.
3D structure databasesPDB 1HVY; X-ray; 1.90 A; A/B/C/D=26-313.
3D structure databasesPDB 1HW3; X-ray; 2.00 A; A=1-313.
3D structure databasesPDB 1HW4; X-ray; 2.06 A; A=1-313.
3D structure databasesPDB 1HZW; X-ray; 2.00 A; A/B=1-313.
3D structure databasesPDB 1I00; X-ray; 2.50 A; A/B=1-313.
3D structure databasesPDB 1JU6; X-ray; 2.89 A; A/B/C/D=1-313.
3D structure databasesPDB 1JUJ; X-ray; 3.00 A; A/B/C/D=1-313.
3D structure databasesPDB 1YPV; X-ray; 1.80 A; A=1-313.
3D structure databasesPDB 2ONB; X-ray; 2.70 A; A=1-313.
3D structure databasesPDB 2RD8; X-ray; 2.50 A; A/B=1-313.
3D structure databasesPDB 2RDA; X-ray; 2.67 A; A/B/C/D/E/F=1-313.
3D structure databasesPDB 3EAW; X-ray; 1.86 A; X=1-313.
3D structure databasesPDB 3EBU; X-ray; 2.05 A; A=1-313.
3D structure databasesPDB 3ED7; X-ray; 1.56 A; A=26-313.
3D structure databasesPDB 3EDW; X-ray; 1.75 A; X=1-313.
3D structure databasesPDB 3EF9; X-ray; 3.20 A; A=1-313.
3D structure databasesPDB 3EGY; X-ray; 2.18 A; X=1-313.
3D structure databasesPDB 3EHI; X-ray; 2.00 A; X=1-313.
3D structure databasesPDB 3EJL; X-ray; 3.20 A; A/B/C/D=1-313.
3D structure databasesPDB 3GG5; X-ray; 2.77 A; A/B/C/D=1-313.
3D structure databasesPDB 3GH0; X-ray; 1.56 A; A=1-313.
3D structure databasesPDB 3GH2; X-ray; 1.75 A; X=1-313.
3D structure databasesPDB 3H9K; X-ray; 2.65 A; A/B/C/D/E=1-313.
3D structure databasesPDB 3HB8; X-ray; 2.74 A; A/B/C/D/E=1-313.
3D structure databasesPDB 3N5E; X-ray; 2.26 A; A/B=1-313.
3D structure databasesPDB 3N5G; X-ray; 2.27 A; A=1-313.
3D structure databasesPDB 3OB7; X-ray; 2.75 A; A/B/C/D/E=1-313.
3D structure databasesPDB 4E28; X-ray; 2.30 A; A=1-313.
3D structure databasesPDB 4FGT; X-ray; 2.00 A; A=1-311.
3D structure databasesPDB 4G2O; X-ray; 2.25 A; X=1-313.
3D structure databasesPDB 4G6W; X-ray; 2.30 A; X=1-313.
3D structure databasesPDB 4GD7; X-ray; 2.29 A; A=1-313.
3D structure databasesPDB 4GYH; X-ray; 3.00 A; A=1-313.
3D structure databasesPDB 4H1I; X-ray; 3.10 A; A/B/C/D=1-313.
3D structure databasesPDB 4JEF; X-ray; 2.31 A; A=26-311.
3D structure databasesPDB 4KPW; X-ray; 2.03 A; A=1-313.
3D structure databasesPDBsum 1HVY; -.
3D structure databasesPDBsum 1HW3; -.
3D structure databasesPDBsum 1HW4; -.
3D structure databasesPDBsum 1HZW; -.
3D structure databasesPDBsum 1I00; -.
3D structure databasesPDBsum 1JU6; -.
3D structure databasesPDBsum 1JUJ; -.
3D structure databasesPDBsum 1YPV; -.
3D structure databasesPDBsum 2ONB; -.
3D structure databasesPDBsum 2RD8; -.
3D structure databasesPDBsum 2RDA; -.
3D structure databasesPDBsum 3EAW; -.
3D structure databasesPDBsum 3EBU; -.
3D structure databasesPDBsum 3ED7; -.
3D structure databasesPDBsum 3EDW; -.
3D structure databasesPDBsum 3EF9; -.
3D structure databasesPDBsum 3EGY; -.
3D structure databasesPDBsum 3EHI; -.
3D structure databasesPDBsum 3EJL; -.
3D structure databasesPDBsum 3GG5; -.
3D structure databasesPDBsum 3GH0; -.
3D structure databasesPDBsum 3GH2; -.
3D structure databasesPDBsum 3H9K; -.
3D structure databasesPDBsum 3HB8; -.
3D structure databasesPDBsum 3N5E; -.
3D structure databasesPDBsum 3N5G; -.
3D structure databasesPDBsum 3OB7; -.
3D structure databasesPDBsum 4E28; -.
3D structure databasesPDBsum 4FGT; -.
3D structure databasesPDBsum 4G2O; -.
3D structure databasesPDBsum 4G6W; -.
3D structure databasesPDBsum 4GD7; -.
3D structure databasesPDBsum 4GYH; -.
3D structure databasesPDBsum 4H1I; -.
3D structure databasesPDBsum 4JEF; -.
3D structure databasesPDBsum 4KPW; -.
3D structure databasesProteinModelPortal P04818; -.
3D structure databasesSMR P04818; 1-313.
Protocols and materials databasesDNASU 7298; -.
Phylogenomic databaseseggNOG COG0207; -.
Phylogenomic databasesGeneTree ENSGT00390000014786; -.
Phylogenomic databasesHOGENOM HOG000257899; -.
Phylogenomic databasesHOVERGEN HBG001934; -.
Phylogenomic databasesInParanoid P04818; -.
Phylogenomic databasesKO K00560; -.
Phylogenomic databasesOMA ELLWIYQ; -.
Phylogenomic databasesOrthoDB EOG725DHX; -.
Phylogenomic databasesPhylomeDB P04818; -.
Phylogenomic databasesTreeFam TF353027; -.
Organism-specific databasesCTD 7298; -.
Organism-specific databasesGeneCards GC18P000657; -.
Organism-specific databasesHGNC HGNC:12441; TYMS.
Organism-specific databasesHPA CAB002784; -.
Organism-specific databasesMIM 188350; gene.
Organism-specific databasesneXtProt NX_P04818; -.
Organism-specific databasesOrphanet 240839; 5-fluorouracil toxicity.
Organism-specific databasesOrphanet 240855; Capecitabine toxicity.
Organism-specific databasesOrphanet 240955; Susceptibility to adverse reaction due to 5-fluorouracil treatment.
Organism-specific databasesOrphanet 240963; Susceptibility to adverse reaction due to capecitabine treatment.
Organism-specific databasesPharmGKB PA359; -.
ChemistryBindingDB P04818; -.
ChemistryChEMBL CHEMBL1952; -.
ChemistryDrugBank DB01101; Capecitabine.
ChemistryDrugBank DB00322; Floxuridine.
ChemistryDrugBank DB00544; Fluorouracil.
ChemistryDrugBank DB00441; Gemcitabine.
ChemistryDrugBank DB00650; Leucovorin.
ChemistryDrugBank DB00563; Methotrexate.
ChemistryDrugBank DB00642; Pemetrexed.
ChemistryDrugBank DB06813; Pralatrexate.
ChemistryDrugBank DB00293; Raltitrexed.
ChemistryDrugBank DB00432; Trifluridine.
ChemistryDrugBank DB00440; Trimethoprim.
ChemistryGuidetoPHARMACOLOGY 2642; -.
OtherChiTaRS TYMS; human.
OtherEvolutionaryTrace P04818; -.
OtherGeneWiki Thymidylate_synthase; -.
OtherGenomeRNAi 7298; -.
OtherNextBio 28543; -.
OtherPRO PR:P04818; -.



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