Cancer Cell Metabolism Database ~~ Bioinformatics and Systems Medicine Laboratory ~~

Cancer Cell Metabolism Gene Database

Cancer Cell Metabolism Gene DB

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Gene-Gene Network

* Using all Interacting genes, we can get KEGG pathway information from DAVID.

Interacting Genes (from Pathway Commons)

Target Genes	DBs	Relations
DatabaseofInteractingProteins	interacts-with	INSR,
DatabaseofInteractingProteins	neighbor-of	INSR,
NCIPathwayInteractionDatabase	controls-phosphorylation-of	AKT1,AKT2,CAV1,CBL, DOK1,INPP5D,PPP1R3A,PTPN1, SGK1,SH2B2,
	controls-state-change-of	AKT1,AKT2,CAV1,CBL, DOK1,HRAS,INPP5D,PIK3CA, PIK3R1,PPP1CC,PPP1R3A,PRKCI, PRKCZ,PTPN1,PTPN2,SGK1, SH2B2,SORBS1,
	controls-transport-of	AKT1,AKT2,PTPN2,
	controls-expression-of	ALAS1,FOXA1,IGFBP1,PTPN1,
	in-complex-with	INSR,IRS1,NCK2,PDPK1, PTPN11,PTPN1,SHC1,SOS1,
	neighbor-of	INSR,IRS1,IRS2,ITGA6, ITGAV,ITGB3,ITGB4,JAK1, JAK2,JAK3,LCK,LYN, MET,MS4A2,NCK1,NCK2, NF1,NOX4,NR3C1,PDGFB, PDGFRA,PDGFRB,PDPK1,PIK3CA, PIK3CB,PIK3R1,PPP1CC,PPP1R3A, PRKCI,PRKCZ,PTPN11,PTPN1, PTPN2,PTPRA,RAC1,RASA1, RET,RHOA,RPS6KB1,SGK1, SH2B2,SHANK3,SHC1,SORBS1, SOS1,SRC,SYK,TXN, VAV1,VEGFC,
PANTHERPathway	in-complex-with	INSRR,INSR,
	neighbor-of	INSRR,INSR,IRS1,IRS2, IRS4,
	controls-phosphorylation-of	IRS1,IRS2,IRS4,
	controls-state-change-of	IRS1,IRS2,IRS4,
BioGRID	interacts-with	KMT2A,MAPK6,NOV,RB1, TXNDC17,
BioGRID	neighbor-of	KMT2A,MAPK6,NOV,RB1, TXNDC17,
HPRD	interacts-with	INSR,LRP2,NOV,RB1, SYTL4,TXNDC17,
HPRD	neighbor-of	INSR,LRP2,NOV,RB1, SYTL4,TXNDC17,
IntAct	interacts-with	MAPK6,TBC1D1,
IntAct	neighbor-of	MAPK6,TBC1D1,
Reactome	controls-state-change-of	DOK1,GHRL,INSR,IRS1, IRS2,SHC1,
	controls-transport-of	GHRL,
	in-complex-with	INSR,IRS1,IRS2,SHC1,
	neighbor-of	INSR,IRS1,IRS2,ITM2B, KIF5A,KIF5B,KIF5C,LEP, LTF,LYZ,MAFA,MFGE8, MYO5A,NKX2-2,NPPA,PAX6, PCSK1,PCSK2,PDX1,PRL, RAB27A,SAA1,SEMG1,SHC1, SNAP25,SNCA,STX1A,STXBP1, SYT5,TGFBI,TTR,VAMP2,