Cancer Cell Metabolism Database ~~ Bioinformatics and Systems Medicine Laboratory ~~

Cancer Cell Metabolism Gene Database

Cancer Cell Metabolism Gene DB

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Gene-Gene Network

* Using all Interacting genes, we can get KEGG pathway information from DAVID.

Interacting Genes (from Pathway Commons)

Target Genes	DBs	Relations
DatabaseofInteractingProteins	interacts-with	PIK3CG,PIK3R4,TP63,UVRAG,
DatabaseofInteractingProteins	neighbor-of	PIK3CG,PIK3R4,TP63,UVRAG,
PANTHERPathway	controls-phosphorylation-of	AKT1,AKT2,AKT3,SPRY1, SPRY2,SPRY3,SPRY4,
	controls-state-change-of	AKT1,AKT2,AKT3,ARHGAP1, ARHGAP8,HRAS,MRAS,NRAS, PDPK1,PRKCA,PRKCB,PRKCD, PRKCE,PRKCG,PRKCH,PRKCI, PRKCQ,PRKCZ,PRKD1,PRKD2, PRKD3,PTK2,RRAS2,RRAS, SPRY1,SPRY2,SPRY3,SPRY4,
	catalysis-precedes	PIK3CA,PIK3CB,PIK3CD,PIK3CG, PIK3R1,PIK3R2,PIK3R3,PTEN,
	in-complex-with	PIK3CA,PLCG1,PLCG2,PTPN6, RASA1,RASA2,RASA4B,RASA4, RASAL2,SHC1,SHC2,SHC3, SOS1,SOS2,STAT1,STAT2, STAT3,STAT4,STAT5A,STAT5B, STAT6,
	neighbor-of	PIK3CA,PIK3CB,PIK3CD,PIK3CG, PIK3R1,PIK3R2,PIK3R3,PIK3R5, PLCG1,PLCG2,PRKCA,PRKCB, PRKCD,PRKCE,PRKCG,PRKCH, PRKCI,PRKCQ,PRKCZ,PRKD1, PRKD2,PRKD3,PTEN,PTK2B, PTK2,PTPN6,RASA1,RASA2, RASA4B,RASA4,RASAL2,RHOA, RHOB,RHOC,RRAS2,RRAS, SHC1,SHC2,SHC3,SOS1, SOS2,SPRY1,SPRY2,SPRY3, SPRY4,STAT1,STAT2,STAT3, STAT4,STAT5A,STAT5B,STAT6, TEK,VEGFA,
BioGRID	interacts-with	PIK3R4,PRMT5,RAB5A,RNF2, SUMO1,TRIM28,UBC,USP11, UVRAG,YWHAG,
BioGRID	neighbor-of	PIK3R4,PRMT5,RAB5A,RNF2, SUMO1,TRIM28,UBC,USP11, UVRAG,YWHAG,
CORUM	in-complex-with	PIK3R4,
HPRD	interacts-with	PIK3R4,PITPNA,YWHAG,
HPRD	neighbor-of	PIK3R4,PITPNA,YWHAG,
HumanCyc	neighbor-of	PIK3CG,PIK3R4,
	in-complex-with	PIK3R4,
	catalysis-precedes	PIKFYVE,PIP4K2A,
IntAct	interacts-with	PIK3R4,PPP2R2D,PRKDC,PTOV1, PTPRA,PURB,RAB5A,RB1CC1, RGPD4,RPF2,RPS27L,SEH1L, SF3A1,SH3GLB1,SH3GLB2,SLC27A4, SMC1A,SMC3,SPTLC1,SRP72, TBC1D7,TCOF1,TECPR1,TFCP2, TGFBRAP1,TOP2B,TP53BP2,TRABD, TSC1,TUBAL3,USP10,USP11, UVRAG,VPS18,VPS33A,WDR6, WDR82,WIPI1,YWHAG,ZNF768, ZWINT,
IntAct	neighbor-of	PIK3R4,PPP2R2D,PRKDC,PTOV1, PTPRA,PURB,RAB5A,RB1CC1, RGPD4,RPF2,RPS27L,SEH1L, SF3A1,SH3GLB1,SH3GLB2,SLC27A4, SMC1A,SMC3,SPTLC1,SRP72, TBC1D7,TCOF1,TECPR1,TFCP2, TGFBRAP1,TOP2B,TP53BP2,TRABD, TSC1,TUBAL3,USP10,USP11, UVRAG,VPS18,VPS33A,WDR6, WDR82,WIPI1,YWHAG,ZNF768, ZWINT,
Reactome	controls-state-change-of	AKT2,PDPK1,
	catalysis-precedes	FIG4,PIKFYVE,VAC14,
	neighbor-of	PIK3CA,PIK3CB,PIK3R1,PIK3R2, PIK3R4,PTPN11,TLR9,ZFYVE20,
	in-complex-with	PIK3R4,TLR9,