DegronMD - A1L020(MEX3A)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A398T	TCGA-AA-3492	COAD	TCGA	ASSSS	DEG_SPOP_SBC_1	408:412	Mutation rewiring degron network	0.0556
p.A398T	TCGA-AG-A00C	READ	TCGA	ASSSS	DEG_SPOP_SBC_1	408:412	Mutation rewiring degron network	0.0556
p.A398T	TCGA-G4-6320	COAD	TCGA	ASSSS	DEG_SPOP_SBC_1	408:412	Mutation rewiring degron network	0.0556
p.A398T	DO8159	COAD	ICGC	ASSSS	DEG_SPOP_SBC_1	408:412	Mutation rewiring degron network	0.0556
p.A398T	DO8224	COAD	ICGC	ASSSS	DEG_SPOP_SBC_1	408:412	Mutation rewiring degron network	0.0556
p.S407C	TCGA-G2-A3IE	BLCA	TCGA	ASSSS	DEG_SPOP_SBC_1	408:412	Mutation rewiring degron network	0.3056
p.S407C	DO767	BLCA	ICGC	ASSSS	DEG_SPOP_SBC_1	408:412	Mutation rewiring degron network	0.3056
p.A420P	DO222780	BTCA	ICGC	ASSSS	DEG_SPOP_SBC_1	408:412	Mutation rewiring degron network	0.1111
p.S402F	DO220901	MELA	ICGC	ASSSS	DEG_SPOP_SBC_1	408:412	Mutation rewiring degron network	0.1667
p.S410Y	DO47747	STAD	ICGC	ASSSS	DEG_SPOP_SBC_1	408:412	Mutation altering degron motif	0.712
p.L404P	SIDM01618	B-Lymphoblastic Leukemia	GDSC	ASSSS	DEG_SPOP_SBC_1	408:412	Mutation rewiring degron network	0.2222

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons