DegronMD - A1L1A6(IGSF23)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.M27I	DO233942	GACA	ICGC	PPTTT	DEG_SPOP_SBC_1	19:23	Mutation rewiring degron network	0.2222
p.M27T	DO35593	PBCA	ICGC	PPTTT	DEG_SPOP_SBC_1	19:23	Mutation rewiring degron network	0.2222
p.M27T	SIDM00025	Head and Neck Carcinoma	GDSC	PPTTT	DEG_SPOP_SBC_1	19:23	Mutation rewiring degron network	0.2222
p.M27T	SIDM00992	Thyroid Gland Carcinoma	GDSC	PPTTT	DEG_SPOP_SBC_1	19:23	Mutation rewiring degron network	0.2222
p.M27T	SIDM00650	Small Cell Lung Carcinoma	GDSC	PPTTT	DEG_SPOP_SBC_1	19:23	Mutation rewiring degron network	0.2222
p.M27T	SIDM00223	Small Cell Lung Carcinoma	GDSC	PPTTT	DEG_SPOP_SBC_1	19:23	Mutation rewiring degron network	0.2222
p.M27T	SIDM00710	Small Cell Lung Carcinoma	GDSC	PPTTT	DEG_SPOP_SBC_1	19:23	Mutation rewiring degron network	0.2222
p.M27T	SIDM01220	Glioma	GDSC	PPTTT	DEG_SPOP_SBC_1	19:23	Mutation rewiring degron network	0.2222
p.M27T	SIDM01681	Non-Cancerous	GDSC	PPTTT	DEG_SPOP_SBC_1	19:23	Mutation rewiring degron network	0.2222
p.M27T	SIDM00839	Colorectal Carcinoma	GDSC	PPTTT	DEG_SPOP_SBC_1	19:23	Mutation rewiring degron network	0.2222
p.L9H	DO229453	SKCA	ICGC	PPTTT	DEG_SPOP_SBC_1	19:23	Mutation rewiring degron network	0.0556
p.P15Q	SIDM00935	Other Solid Cancers	GDSC	PPTTT	DEG_SPOP_SBC_1	19:23	Mutation rewiring degron network	0.2222
p.P15Q	CAL-39	vulva	COSMIC	PPTTT	DEG_SPOP_SBC_1	19:23	Mutation rewiring degron network	0.2222
p.K30R	SIDM00151	Ovarian Carcinoma	GDSC	PPTTT	DEG_SPOP_SBC_1	19:23	Mutation substituting flanking lysine	0.25
p.K30R	ACH-000966	Ovarian Cancer	CCLE	PPTTT	DEG_SPOP_SBC_1	19:23	Mutation substituting flanking lysine	0.25
p.K30R	IGROV-1	ovary	COSMIC	PPTTT	DEG_SPOP_SBC_1	19:23	Mutation substituting flanking lysine	0.25
p.P10L	ACH-001567	Skin Cancer	CCLE	PPTTT	DEG_SPOP_SBC_1	19:23	Mutation rewiring degron network	0.0833

Kaplan plot for IGSF23 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

IGSF23

UniProt ID: A1L1A6

Entrez ID: 147710

Protein name: Immunoglobulin superfamily member 23

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for IGSF23 in