DegronMD - A4D0V7(CPED1)

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.Y102C	TCGA-A5-A1OF	UCEC	TCGA	PPFY	ITCH	104:107	Mutation rewiring degron network	0.2778
p.Y102C	DO42568	UCEC	ICGC	PPFY	ITCH	104:107	Mutation rewiring degron network	0.2778
p.Q113E	TCGA-C8-A27B	BRCA	TCGA	PPFY	ITCH	104:107	Mutation rewiring degron network	0.1667
p.Q113E	DO4623	BRCA	ICGC	PPFY	ITCH	104:107	Mutation rewiring degron network	0.1667
p.L101F	TCGA-CV-A45W	HNSC	TCGA	PPFY	ITCH	104:107	Mutation rewiring degron network	0.25
p.L101F	DO52060	HNSC	ICGC	PPFY	ITCH	104:107	Mutation rewiring degron network	0.25
p.T110K	TCGA-L5-A4OJ	ESCA	TCGA	PPFY	ITCH	104:107	Mutation rewiring degron network	0.25
p.P105L	TCGA-OD-A75X	SKCM	TCGA	PPFY	ITCH	104:107	Mutation altering degron motif	0.7582
p.P105L	DO48601	SKCM	ICGC	PPFY	ITCH	104:107	Mutation altering degron motif	0.7582
p.R97Q	DO224768	BRCA	ICGC	PPFY	ITCH	104:107	Mutation rewiring degron network	0.1389
p.R97Q	SIDM00220	Ovarian Carcinoma	GDSC	PPFY	ITCH	104:107	Mutation rewiring degron network	0.1389
p.R97Q	ACH-000962	Ovarian Cancer	CCLE	PPFY	ITCH	104:107	Mutation rewiring degron network	0.1389
p.R97Q	ACH-001145	Ovarian Cancer	CCLE	PPFY	ITCH	104:107	Mutation rewiring degron network	0.1389
p.A97V	DO230336	COCA	ICGC	PPFY	ITCH	104:107	Mutation rewiring degron network	0.1389
p.Q113H	DO233623	GACA	ICGC	PPFY	ITCH	104:107	Mutation rewiring degron network	0.1667
p.M107I	DO49670	LIAD	ICGC	PPFY	ITCH	104:107	Mutation altering degron motif	0.7618
p.K113N	DO24140	LUAD	ICGC	PPFY	ITCH	104:107	Mutation rewiring degron network	0.1667
p.L112F	DO52687	MALY	ICGC	PPFY	ITCH	104:107	Mutation rewiring degron network	0.1944
p.A99V	DO32924	PACA	ICGC	PPFY	ITCH	104:107	Mutation rewiring degron network	0.1944
p.R96K	DO37831	SKCM	ICGC	PPFY	ITCH	104:107	Mutation rewiring degron network	0.1111
p.Q102H	DO42568	UCEC	ICGC	PPFY	ITCH	104:107	Mutation rewiring degron network	0.2778
p.H117D	SIDM01126	Small Cell Lung Carcinoma	GDSC	PPFY	ITCH	104:107	Mutation rewiring degron network	0.0556
p.H117D	ACH-001599	Lung Cancer	CCLE	PPFY	ITCH	104:107	Mutation rewiring degron network	0.0556
p.H117D	NCI-H64	lung	COSMIC	PPFY	ITCH	104:107	Mutation rewiring degron network	0.0556
p.Y107C	SIDM01318	Hepatocellular Carcinoma	GDSC	PPFY	ITCH	104:107	Mutation altering degron motif	0.7087
p.H95N	ACH-000870	Lung Cancer	CCLE	PPFY	ITCH	104:107	Mutation rewiring degron network	0.0833
p.A117E	H2818	pleura	COSMIC	PPFY	ITCH	104:107	Mutation rewiring degron network	0.0556

DegronMD: protein-targeted degradation, mutation and drug response to degrons

CPED1

UniProt ID: A4D0V7

Entrez ID: 79974

Protein name: Cadherin-like and PC-esterase domain-containing protein 1

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for CPED1 in