DENND11
UniProt ID: A4D1U4
Entrez ID: 57189
Protein name: DENN domain-containing protein 11 (DENND11) (Protein LCHN)
External links: UniprotKB HGNC RefSeq COSMIC
Please click HERE
for better display.
FUNCTION: Probable guanine nucleotide exchange factor (GEF). May promote the exchange of GDP to GTP, converting inactive GDP-bound small GTPases into their active GTP-bound form (Probable). May play a role in neuritogenesis, as well as in neuronal recovery and/or restructuring in the hippocampus fol...
FUNCTION: Probable guanine nucleotide exchange factor (GEF). May promote the exchange of GDP to GTP, converting inactive GDP-bound small GTPases into their active GTP-bound form (Probable). May play a role in neuritogenesis, as well as in neuronal recovery and/or restructuring in the hippocampus following transient cerebral ischemia (By similarity). {ECO:0000250|UniProtKB:Q0PGW2, ECO:0000305}.
View more >>
GO - Biological processes (BP):
...
View more >>
GO - Molecular function (MF):
guanyl-nucleotide exchange factor activity [GO:0005085]...
guanyl-nucleotide exchange factor activity [GO:0005085]
View more >>
GO - Cellular component (CC):
cytoplasm [GO:0005737]...
cytoplasm [GO:0005737]
View more >>
DENND11
Control panel
Show dataset:
Show Degron:
All sites
Degron
Degron
Filter mutation sites
All sites
Minimum 5 samples
Minimum 10 samples
Minimum 5 samples
Minimum 10 samples
Data table is loading....
Kaplan plot for DENND11 in
Download patient class data (Lower:Upper = 50%:50%)
*NOTE: the Kaplan plots were collected from OncoLnc