DegronMD - A6NGY3(C5orf52)

GO - Biological processes (BP): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R39H	TCGA-AP-A1DV	UCEC	TCGA	ATTSS	DEG_SPOP_SBC_1	25:29	Mutation rewiring degron network	0.0556
p.R39H	DO43186	UCEC	ICGC	ATTSS	DEG_SPOP_SBC_1	25:29	Mutation rewiring degron network	0.0556
p.R39H	SIDM01154	T-Lymphoblastic Leukemia	GDSC	ATTSS	DEG_SPOP_SBC_1	25:29	Mutation rewiring degron network	0.0556
p.R39H	ACH-000953	Leukemia	CCLE	ATTSS	DEG_SPOP_SBC_1	25:29	Mutation rewiring degron network	0.0556
p.A22T	TCGA-DF-A2KU	UCEC	TCGA	ATTSS	DEG_SPOP_SBC_1	25:29	Mutation rewiring degron network	0.25
p.A22T	DO232224	PBCA	ICGC	ATTSS	DEG_SPOP_SBC_1	25:29	Mutation rewiring degron network	0.25
p.A22T	DO223286	UCEC	ICGC	ATTSS	DEG_SPOP_SBC_1	25:29	Mutation rewiring degron network	0.25
p.S35L	TCGA-EY-A1GI	UCEC	TCGA	ATTSS	DEG_SPOP_SBC_1	25:29	Mutation rewiring degron network	0.1667
p.S35L	DO41211	UCEC	ICGC	ATTSS	DEG_SPOP_SBC_1	25:29	Mutation rewiring degron network	0.1667
p.S35L	SIDM00980	Gastric Carcinoma	GDSC	ATTSS	DEG_SPOP_SBC_1	25:29	Mutation rewiring degron network	0.1667
p.S35L	ACH-000948	Gastric Cancer	CCLE	ATTSS	DEG_SPOP_SBC_1	25:29	Mutation rewiring degron network	0.1667
p.A31T	DO233791	GACA	ICGC	ATTSS	DEG_SPOP_SBC_1	25:29	Mutation rewiring degron network	0.2778
p.A23S	DO229037	LICA	ICGC	ATTSS	DEG_SPOP_SBC_1	25:29	Mutation rewiring degron network	0.2778

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons