DegronMD - A6NI15(MSGN1)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.D142H	TCGA-93-8067	LUAD	TCGA	PPVY	ITCH	152:155	Mutation rewiring degron network	0.0556
p.D142H	DO25113	LUAD	ICGC	PPVY	ITCH	152:155	Mutation rewiring degron network	0.0556
p.H145Y	TCGA-A6-5661	COAD	TCGA	PPVY	ITCH	152:155	Mutation rewiring degron network	0.1389
p.H145Y	DO8634	COAD	ICGC	PPVY	ITCH	152:155	Mutation rewiring degron network	0.1389
p.K164E	TCGA-AX-A0J0	UCEC	TCGA	PPVY	ITCH	152:155	Mutation substituting flanking lysine	0.1944
p.K164E	DO41133	UCEC	ICGC	PPVY	ITCH	152:155	Mutation substituting flanking lysine	0.1944
p.G159D	TCGA-B0-5098	KIRC	TCGA	PPVY	ITCH	152:155	Mutation rewiring degron network	0.2222
p.G159D	DO18938	KIRC	ICGC	PPVY	ITCH	152:155	Mutation rewiring degron network	0.2222
p.P152S	TCGA-BS-A0UF	UCEC	TCGA	PPVY	ITCH	152:155	Mutation altering degron motif	0.6752
p.P152S	DO41488	UCEC	ICGC	PPVY	ITCH	152:155	Mutation altering degron motif	0.6752
p.R148Q	TCGA-CG-4442	STAD	TCGA	PPVY	ITCH	152:155	Mutation rewiring degron network	0.2222
p.R148Q	DO38380	STAD	ICGC	PPVY	ITCH	152:155	Mutation rewiring degron network	0.2222
p.P153H	TCGA-DF-A2KN	UCEC	TCGA	PPVY	ITCH	152:155	Mutation altering degron motif	0.7694
p.P153H	DO223282	UCEC	ICGC	PPVY	ITCH	152:155	Mutation altering degron motif	0.7694
p.S156N	TCGA-DK-A3IL	BLCA	TCGA	PPVY	ITCH	152:155	Mutation rewiring degron network	0.3056
p.S156N	DO555	BLCA	ICGC	PPVY	ITCH	152:155	Mutation rewiring degron network	0.3056
p.P152Q	TCGA-EE-A2GE	SKCM	TCGA	PPVY	ITCH	152:155	Mutation altering degron motif	0.7035
p.P152Q	DO38016	SKCM	ICGC	PPVY	ITCH	152:155	Mutation altering degron motif	0.7035
p.A143V	TCGA-F5-6814	READ	TCGA	PPVY	ITCH	152:155	Mutation rewiring degron network	0.0833
p.A143V	DO36556	READ	ICGC	PPVY	ITCH	152:155	Mutation rewiring degron network	0.0833
p.L162F	DO234201	ESAD	ICGC	PPVY	ITCH	152:155	Mutation rewiring degron network	0.1389
p.V154L	DO227641	PBCA	ICGC	PPVY	ITCH	152:155	Mutation altering degron motif	0.5654
p.G159C	SIDM00499	Prostate Carcinoma	GDSC	PPVY	ITCH	152:155	Mutation rewiring degron network	0.2222
p.G159C	ACH-000956	Prostate Cancer	CCLE	PPVY	ITCH	152:155	Mutation rewiring degron network	0.2222
p.G159C	22RV1	prostate	COSMIC	PPVY	ITCH	152:155	Mutation rewiring degron network	0.2222

Kaplan plot for MSGN1 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

MSGN1

UniProt ID: A6NI15

Entrez ID: 343930

Protein name: Mesogenin-1 (Paraxial mesoderm-specific mesogenin1) (pMesogenin1) (pMsgn1)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for MSGN1 in