DegronMD - A6NMB9(FIGNL2)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P193T	SIDM02015	Colorectal Carcinoma	GDSC	PPGY	ITCH	193:196	Mutation altering degron motif	0.7031
p.P28T	SIDM00683	Prostate Carcinoma	GDSC	VSSTT	DEG_SPOP_SBC_1	21:25	Mutation rewiring degron network	0.25
p.P26L	SIDM00856	Other Solid Cancers	GDSC	VSSTT	DEG_SPOP_SBC_1	21:25	Mutation rewiring degron network	0.3056
p.S23T	SIDM00637	B-Cell Non-Hodgkin's Lymphoma	GDSC	VSSTT	DEG_SPOP_SBC_1	21:25	Mutation altering degron motif	0.6005

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons