DegronMD - A6NMZ2(SNTN)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R32W	TCGA-85-A5B5	LUSC	TCGA	APTST	DEG_SPOP_SBC_1	24:28	Mutation rewiring degron network	0.2222
p.R32W	DO50102	LUSC	ICGC	APTST	DEG_SPOP_SBC_1	24:28	Mutation rewiring degron network	0.2222
p.P35S	TCGA-BR-6457	STAD	TCGA	APTST	DEG_SPOP_SBC_1	24:28	Mutation rewiring degron network	0.1389
p.P35S	DO38759	STAD	ICGC	APTST	DEG_SPOP_SBC_1	24:28	Mutation rewiring degron network	0.1389
p.D18N	TCGA-BR-A4PE	STAD	TCGA	APTST	DEG_SPOP_SBC_1	24:28	Mutation rewiring degron network	0.1667
p.D18N	TCGA-FR-A726	SKCM	TCGA	APTST	DEG_SPOP_SBC_1	24:28	Mutation rewiring degron network	0.1667
p.D18N	DO48665	SKCM	ICGC	APTST	DEG_SPOP_SBC_1	24:28	Mutation rewiring degron network	0.1667
p.D18N	DO47773	STAD	ICGC	APTST	DEG_SPOP_SBC_1	24:28	Mutation rewiring degron network	0.1667
p.D18H	TCGA-DC-6157	READ	TCGA	APTST	DEG_SPOP_SBC_1	24:28	Mutation rewiring degron network	0.1667
p.D18H	DO36383	READ	ICGC	APTST	DEG_SPOP_SBC_1	24:28	Mutation rewiring degron network	0.1667
p.P19L	TCGA-DK-A6AW	BLCA	TCGA	APTST	DEG_SPOP_SBC_1	24:28	Mutation rewiring degron network	0.1944
p.P19L	DO48566	BLCA	ICGC	APTST	DEG_SPOP_SBC_1	24:28	Mutation rewiring degron network	0.1944
p.T26A	TCGA-E5-A4TZ	BLCA	TCGA	APTST	DEG_SPOP_SBC_1	24:28	Mutation altering degron motif	0.7139
p.T26A	DO44055	BLCA	ICGC	APTST	DEG_SPOP_SBC_1	24:28	Mutation altering degron motif	0.7139
p.P25T	TCGA-EE-A3AA	SKCM	TCGA	APTST	DEG_SPOP_SBC_1	24:28	Mutation altering degron motif	0.5919
p.P25T	TCGA-EE-A3AD	SKCM	TCGA	APTST	DEG_SPOP_SBC_1	24:28	Mutation altering degron motif	0.5919
p.P25T	DO37571	SKCM	ICGC	APTST	DEG_SPOP_SBC_1	24:28	Mutation altering degron motif	0.5919
p.P25T	DO37707	SKCM	ICGC	APTST	DEG_SPOP_SBC_1	24:28	Mutation altering degron motif	0.5919
p.C29R	TCGA-FI-A2D5	UCEC	TCGA	APTST	DEG_SPOP_SBC_1	24:28	Mutation rewiring degron network	0.3056
p.C29R	DO41331	UCEC	ICGC	APTST	DEG_SPOP_SBC_1	24:28	Mutation rewiring degron network	0.3056
p.G17E	TCGA-GN-A266	SKCM	TCGA	APTST	DEG_SPOP_SBC_1	24:28	Mutation rewiring degron network	0.1389
p.G17E	DO37432	SKCM	ICGC	APTST	DEG_SPOP_SBC_1	24:28	Mutation rewiring degron network	0.1389
p.M34L	TCGA-WC-A882	UVM	TCGA	APTST	DEG_SPOP_SBC_1	24:28	Mutation rewiring degron network	0.1667
p.A30T	DO233884	GACA	ICGC	APTST	DEG_SPOP_SBC_1	24:28	Mutation rewiring degron network	0.2778
p.P21S	DO218863	SKCA	ICGC	APTST	DEG_SPOP_SBC_1	24:28	Mutation rewiring degron network	0.25
p.G17R	SIDM01106	Melanoma	GDSC	APTST	DEG_SPOP_SBC_1	24:28	Mutation rewiring degron network	0.1389
p.G17R	SK-MEL-24	skin	COSMIC	APTST	DEG_SPOP_SBC_1	24:28	Mutation rewiring degron network	0.1389
p.P17H	ACH-001059	Rhabdoid	CCLE	APTST	DEG_SPOP_SBC_1	24:28	Mutation rewiring degron network	0.1389

Kaplan plot for SNTN in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

SNTN

UniProt ID: A6NMZ2

Entrez ID: 132203

Protein name: Sentan (Protein S100-A1-like) (S100 calcium-binding protein A1-like)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for SNTN in