DegronMD - A8MTQ0(NOTO)

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GO - Molecular function (MF): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A245V	TCGA-AJ-A3BG	UCEC	TCGA	PSSSS	DEG_SPOP_SBC_1	232:236	Mutation rewiring degron network	0.0833
p.A245V	DO42633	UCEC	ICGC	PSSSS	DEG_SPOP_SBC_1	232:236	Mutation rewiring degron network	0.0833
p.S234R	TCGA-B6-A1KN	BRCA	TCGA	PSSSS	DEG_SPOP_SBC_1	232:236	Mutation altering degron motif	0.7427
p.S234R	DO3656	BRCA	ICGC	PSSSS	DEG_SPOP_SBC_1	232:236	Mutation altering degron motif	0.7427
p.A238T	TCGA-FI-A2D5	UCEC	TCGA	PSSSS	DEG_SPOP_SBC_1	232:236	Mutation rewiring degron network	0.2778
p.A238T	DO41331	UCEC	ICGC	PSSSS	DEG_SPOP_SBC_1	232:236	Mutation rewiring degron network	0.2778
p.E246A	TCGA-G3-AAV6	LIHC	TCGA	PSSSS	DEG_SPOP_SBC_1	232:236	Mutation rewiring degron network	0.0556
p.E246A	DO52299	LIHC	ICGC	PSSSS	DEG_SPOP_SBC_1	232:236	Mutation rewiring degron network	0.0556
p.A238S	DO228405	LICA	ICGC	PSSSS	DEG_SPOP_SBC_1	232:236	Mutation rewiring degron network	0.2778
p.A238S	DO229041	LICA	ICGC	PSSSS	DEG_SPOP_SBC_1	232:236	Mutation rewiring degron network	0.2778
p.S228C	DO48732	LIRI	ICGC	PSSSS	DEG_SPOP_SBC_1	232:236	Mutation rewiring degron network	0.2222

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons