FUNCTION: Testis-specific potassium channel activated by both intracellular pH and membrane voltage that mediates export of K(+). May represent the primary spermatozoan K(+) current. In contrast to KCNMA1/SLO1, it is not activated by Ca(2+) or Mg(2+). Critical for fertility. May play an important ro...
FUNCTION: Testis-specific potassium channel activated by both intracellular pH and membrane voltage that mediates export of K(+). May represent the primary spermatozoan K(+) current. In contrast to KCNMA1/SLO1, it is not activated by Ca(2+) or Mg(2+). Critical for fertility. May play an important role in sperm osmoregulation required for the acquisition of normal morphology and motility when faced with osmotic challenges, such as those experienced after mixing with seminal fluid and entry into the vagina. {ECO:0000269|PubMed:23129643}.
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GO - Biological processes (BP):
regulation of ion transmembrane transport [GO:0034765]; reproductive process [GO:0022414]...
regulation of ion transmembrane transport [GO:0034765]; reproductive process [GO:0022414]
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GO - Molecular function (MF):
potassium channel activity [GO:0005267]; voltage-gated ion channel activity [GO:0005244]...
potassium channel activity [GO:0005267]; voltage-gated ion channel activity [GO:0005244]
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GO - Cellular component (CC):
integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]...
integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]
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