DegronMD - A8MZG2(C16orf90)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S137Y	TCGA-55-8506	LUAD	TCGA	ASSSS	DEG_SPOP_SBC_1	134:138	Mutation altering degron motif	0.712
p.S137Y	DO45390	LUAD	ICGC	ASSSS	DEG_SPOP_SBC_1	134:138	Mutation altering degron motif	0.712
p.D142Y	TCGA-A5-A1OF	UCEC	TCGA	ASSSS	DEG_SPOP_SBC_1	134:138	Mutation rewiring degron network	0.2222
p.D142Y	DO42568	UCEC	ICGC	ASSSS	DEG_SPOP_SBC_1	134:138	Mutation rewiring degron network	0.2222
p.D142H	TCGA-DK-A3WW	BLCA	TCGA	ASSSS	DEG_SPOP_SBC_1	134:138	Mutation rewiring degron network	0.2222
p.D142H	DO481	BLCA	ICGC	ASSSS	DEG_SPOP_SBC_1	134:138	Mutation rewiring degron network	0.2222
p.G131E	TCGA-E6-A1LX	UCEC	TCGA	ASSSS	DEG_SPOP_SBC_1	134:138	Mutation rewiring degron network	0.25
p.G131E	DO41020	UCEC	ICGC	ASSSS	DEG_SPOP_SBC_1	134:138	Mutation rewiring degron network	0.25
p.S135F	TCGA-G3-A3CH	LIHC	TCGA	ASSSS	DEG_SPOP_SBC_1	134:138	Mutation altering degron motif	0.6871
p.S135F	DO22878	LIHC	ICGC	ASSSS	DEG_SPOP_SBC_1	134:138	Mutation altering degron motif	0.6871
p.R124Q	DO34809	PACA	ICGC	ASSSS	DEG_SPOP_SBC_1	134:138	Mutation rewiring degron network	0.0556
p.Q148H	SIDM00573	Glioblastoma	GDSC	ASSSS	DEG_SPOP_SBC_1	134:138	Mutation rewiring degron network	0.0556
p.Q148H	SIDM00235	Kidney Carcinoma	GDSC	ASSSS	DEG_SPOP_SBC_1	134:138	Mutation rewiring degron network	0.0556
p.Q148H	SIDM00045	Gastric Carcinoma	GDSC	ASSSS	DEG_SPOP_SBC_1	134:138	Mutation rewiring degron network	0.0556
p.Q148H	SIDM01608	Endometrial Carcinoma	GDSC	ASSSS	DEG_SPOP_SBC_1	134:138	Mutation rewiring degron network	0.0556
p.Q148H	SIDM01464	Pancreatic Carcinoma	GDSC	ASSSS	DEG_SPOP_SBC_1	134:138	Mutation rewiring degron network	0.0556
p.Q148H	SIDM01432	Kidney Carcinoma	GDSC	ASSSS	DEG_SPOP_SBC_1	134:138	Mutation rewiring degron network	0.0556

Kaplan plot for C16orf90 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

C16orf90

UniProt ID: A8MZG2

Entrez ID: 646174

Protein name: Uncharacterized protein C16orf90

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for C16orf90 in