DegronMD - D6RGX4(FAM90A26)

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GO - Molecular function (MF): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.D449N	DO220851	MELA	ICGC	VSSSS	DEG_SPOP_SBC_1	452:456	Mutation rewiring degron network	0.25
p.H153N	SIDM00352	Ovarian Carcinoma	GDSC	VHTTS	DEG_SPOP_SBC_1	152:156	Mutation altering degron motif	0.6312
p.H153N	ACH-000719	Ovarian Cancer	CCLE	VHTTS	DEG_SPOP_SBC_1	152:156	Mutation altering degron motif	0.6312
p.H153P	SIDM00352	Ovarian Carcinoma	GDSC	VHTTS	DEG_SPOP_SBC_1	152:156	Mutation altering degron motif	0.6583
p.H153P	ACH-000719	Ovarian Cancer	CCLE	VHTTS	DEG_SPOP_SBC_1	152:156	Mutation altering degron motif	0.6583
p.R160H	SIDM00858	Osteosarcoma	GDSC	VHTTS	DEG_SPOP_SBC_1	152:156	Mutation rewiring degron network	0.2222
p.A166S	SIDM01074	Glioblastoma	GDSC	VHTTS	DEG_SPOP_SBC_1	152:156	Mutation rewiring degron network	0.0556

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons