DegronMD - O00299(CLIC1)

CLIC1

Please click HERE for better display.

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P91L	TCGA-D9-A6EC	SKCM	TCGA	PPRY	ITCH	90:93	Mutation altering degron motif	0.7582
p.P91L	DO50291	SKCM	ICGC	PPRY	ITCH	90:93	Mutation altering degron motif	0.7582
p.P91S	TCGA-D9-A6EC	SKCM	TCGA	PPRY	ITCH	90:93	Mutation altering degron motif	0.6752
p.P91S	DO50291	SKCM	ICGC	PPRY	ITCH	90:93	Mutation altering degron motif	0.6752
p.I80M	TCGA-N5-A4R8	UCS	TCGA	PPRY	ITCH	90:93	Mutation rewiring degron network	0.0556
p.C89R	DO52481	COCA	ICGC	PPRY	ITCH	90:93	Mutation rewiring degron network	0.3056
p.C89R	SIDM00048	Non-Small Cell Lung Carcinoma	GDSC	PPRY	ITCH	90:93	Mutation rewiring degron network	0.3056
p.A86T	DO233156	GACA	ICGC	PPRY	ITCH	90:93	Mutation rewiring degron network	0.2222
p.C89W	DO233724	GACA	ICGC	PPRY	ITCH	90:93	Mutation rewiring degron network	0.3056
p.A98T	DO50970	LICA	ICGC	PPRY	ITCH	90:93	Mutation rewiring degron network	0.1944
p.A98T	SIDM00237	Non-Small Cell Lung Carcinoma	GDSC	PPRY	ITCH	90:93	Mutation rewiring degron network	0.1944
p.A98T	ACH-000030	Lung Cancer	CCLE	PPRY	ITCH	90:93	Mutation rewiring degron network	0.1944
p.A98T	ACH-000779	Lung Cancer	CCLE	PPRY	ITCH	90:93	Mutation rewiring degron network	0.1944
p.A98T	PC-14	lung	COSMIC	PPRY	ITCH	90:93	Mutation rewiring degron network	0.1944
p.R92S	SIDM00760	Small Cell Lung Carcinoma	GDSC	PPRY	ITCH	90:93	Mutation altering degron motif	0.6316

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc