DegronMD - O00303(EIF3F)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.V38L	TCGA-CD-8527	STAD	TCGA	PASSS	DEG_SPOP_SBC_1	43:47	Mutation rewiring degron network	0.1944
p.V38L	DO47739	STAD	ICGC	PASSS	DEG_SPOP_SBC_1	43:47	Mutation rewiring degron network	0.1944
p.P37Q	TCGA-D3-A2JO	SKCM	TCGA	PASSS	DEG_SPOP_SBC_1	43:47	Mutation rewiring degron network	0.1667
p.P37Q	DO47619	SKCM	ICGC	PASSS	DEG_SPOP_SBC_1	43:47	Mutation rewiring degron network	0.1667
p.P39S	TCGA-DK-AA75	BLCA	TCGA	PASSS	DEG_SPOP_SBC_1	43:47	Mutation rewiring degron network	0.2222
p.P39S	DO219012	BLCA	ICGC	PASSS	DEG_SPOP_SBC_1	43:47	Mutation rewiring degron network	0.2222
p.A52T	TCGA-FI-A2D5	UCEC	TCGA	PASSS	DEG_SPOP_SBC_1	43:47	Mutation rewiring degron network	0.1944
p.A52T	DO41331	UCEC	ICGC	PASSS	DEG_SPOP_SBC_1	43:47	Mutation rewiring degron network	0.1944
p.E39K	DO514	BLCA	ICGC	PASSS	DEG_SPOP_SBC_1	43:47	Mutation rewiring degron network	0.2222
p.R43Q	DO52483	COCA	ICGC	PASSS	DEG_SPOP_SBC_1	43:47	Mutation altering degron motif	0.7329
p.S34P	DO229248	THCA	ICGC	PASSS	DEG_SPOP_SBC_1	43:47	Mutation rewiring degron network	0.0833
p.P49S	SIDM01163	Non-Small Cell Lung Carcinoma	GDSC	PASSS	DEG_SPOP_SBC_1	43:47	Mutation rewiring degron network	0.2778
p.P49S	ACH-000677	Lung Cancer	CCLE	PASSS	DEG_SPOP_SBC_1	43:47	Mutation rewiring degron network	0.2778
p.S46Y	SIDM00747	Non-Small Cell Lung Carcinoma	GDSC	PASSS	DEG_SPOP_SBC_1	43:47	Mutation altering degron motif	0.8231
p.S46Y	ACH-000744	Lung Cancer	CCLE	PASSS	DEG_SPOP_SBC_1	43:47	Mutation altering degron motif	0.8231
p.S45L	SIDM01775	B-Cell Non-Hodgkin's Lymphoma	GDSC	PASSS	DEG_SPOP_SBC_1	43:47	Mutation altering degron motif	0.7667
p.A44T	ACH-000950	Colon/Colorectal Cancer	CCLE	PASSS	DEG_SPOP_SBC_1	43:47	Mutation altering degron motif	0.6028
p.P43L	ACH-001652	Endometrial/Uterine Cancer	CCLE	PASSS	DEG_SPOP_SBC_1	43:47	Mutation altering degron motif	0.7582

Kaplan plot for EIF3F in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

EIF3F

UniProt ID: O00303

Entrez ID: 8665

Protein name: Eukaryotic translation initiation factor 3 subunit F (eIF3f) (Deubiquitinating enzyme eIF3f) (EC 3.4.19.12) (Eukaryotic translation initiation factor 3 subunit 5) (eIF-3-epsilon) (eIF3 p47)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for EIF3F in