DegronMD - O15178(TBXT)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.Q243K	SIDM01156	Small Cell Lung Carcinoma	GDSC	PGTST	DEG_SPOP_SBC_1	249:253	Mutation rewiring degron network	0.1667
p.Q243K	SW1271	lung	COSMIC	PGTST	DEG_SPOP_SBC_1	249:253	Mutation rewiring degron network	0.1667
p.G250V	SIDM00303	Ovarian Carcinoma	GDSC	PGTST	DEG_SPOP_SBC_1	249:253	Mutation altering degron motif	0.6421
p.G250V	JHOS-4	ovary	COSMIC	PGTST	DEG_SPOP_SBC_1	249:253	Mutation altering degron motif	0.6421
p.V334M	SIDM00091	Ovarian Carcinoma	GDSC	PPTSS	DEG_SPOP_SBC_1	340:344	Mutation rewiring degron network	0.1667
p.T251S	SIDM00631	Breast Carcinoma	GDSC	PGTST	DEG_SPOP_SBC_1	249:253	Mutation altering degron motif	0.6005
p.T251S	MDA-MB-330	breast	COSMIC	PGTST	DEG_SPOP_SBC_1	249:253	Mutation altering degron motif	0.6005
p.S330N	SIDM01608	Endometrial Carcinoma	GDSC	PPTSS	DEG_SPOP_SBC_1	340:344	Mutation rewiring degron network	0.0556

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons