DegronMD - O15195(VILL)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S786I	TCGA-12-0829	GBM	TCGA	VSSTS	DEG_SPOP_SBC_1	785:789	Mutation altering degron motif	0.623
p.S786I	DO11166	GBM	ICGC	VSSTS	DEG_SPOP_SBC_1	785:789	Mutation altering degron motif	0.623
p.G794W	TCGA-19-4068	GBM	TCGA	VSSTS	DEG_SPOP_SBC_1	785:789	Mutation rewiring degron network	0.1944
p.G794W	DO12028	GBM	ICGC	VSSTS	DEG_SPOP_SBC_1	785:789	Mutation rewiring degron network	0.1944
p.R780T	TCGA-86-A4P7	LUAD	TCGA	VSSTS	DEG_SPOP_SBC_1	785:789	Mutation rewiring degron network	0.1944
p.R780T	DO45366	LUAD	ICGC	VSSTS	DEG_SPOP_SBC_1	785:789	Mutation rewiring degron network	0.1944
p.S784Y	TCGA-A5-A0G2	UCEC	TCGA	VSSTS	DEG_SPOP_SBC_1	785:789	Mutation rewiring degron network	0.3056
p.S784Y	DO41235	UCEC	ICGC	VSSTS	DEG_SPOP_SBC_1	785:789	Mutation rewiring degron network	0.3056
p.R798L	TCGA-EE-A2MS	SKCM	TCGA	VSSTS	DEG_SPOP_SBC_1	785:789	Mutation rewiring degron network	0.0833
p.R798L	DO37567	SKCM	ICGC	VSSTS	DEG_SPOP_SBC_1	785:789	Mutation rewiring degron network	0.0833
p.T791M	TCGA-EJ-5507	PRAD	TCGA	VSSTS	DEG_SPOP_SBC_1	785:789	Mutation rewiring degron network	0.2778
p.T791M	DO36257	PRAD	ICGC	VSSTS	DEG_SPOP_SBC_1	785:789	Mutation rewiring degron network	0.2778
p.E799K	TCGA-GD-A3OP	BLCA	TCGA	VSSTS	DEG_SPOP_SBC_1	785:789	Mutation rewiring degron network	0.0556
p.E799K	DO761	BLCA	ICGC	VSSTS	DEG_SPOP_SBC_1	785:789	Mutation rewiring degron network	0.0556
p.R780K	DO234149	ESAD	ICGC	VSSTS	DEG_SPOP_SBC_1	785:789	Mutation rewiring degron network	0.1944
p.R780K	SIDM01270	Esophageal Carcinoma	GDSC	VSSTS	DEG_SPOP_SBC_1	785:789	Mutation rewiring degron network	0.1944
p.A777S	DO228952	LICA	ICGC	VSSTS	DEG_SPOP_SBC_1	785:789	Mutation rewiring degron network	0.1111
p.A790T	SIDM01015	Chronic Myelogenous Leukemia	GDSC	VSSTS	DEG_SPOP_SBC_1	785:789	Mutation rewiring degron network	0.3056
p.A790T	ACH-000326	Leukemia	CCLE	VSSTS	DEG_SPOP_SBC_1	785:789	Mutation rewiring degron network	0.3056
p.A790T	JURL-MK1	haematopoietic and lymphoid tissue	COSMIC	VSSTS	DEG_SPOP_SBC_1	785:789	Mutation rewiring degron network	0.3056

Kaplan plot for VILL in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

VILL

UniProt ID: O15195

Entrez ID: 50853

Protein name: Villin-like protein

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for VILL in