DegronMD - O43313(ATMIN)

ATMIN

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P299L	TCGA-D3-A8GM	SKCM	TCGA	PPRY	ITCH	287:290	Mutation rewiring degron network	0.0833
p.L284V	TCGA-DK-A3IL	BLCA	TCGA	PPRY	ITCH	287:290	Mutation rewiring degron network	0.25
p.R289T	TCGA-E5-A4U1	BLCA	TCGA	PPRY	ITCH	287:290	Mutation altering degron motif	0.6765
p.S280F	DO219621	BRCA	ICGC	PPRY	ITCH	287:290	Mutation rewiring degron network	0.1389
p.D292H	DO44384	CESC	ICGC	PPRY	ITCH	287:290	Mutation rewiring degron network	0.2778
p.C284S	DO228949	LICA	ICGC	PPRY	ITCH	287:290	Mutation rewiring degron network	0.25
p.A277S	DO229009	LICA	ICGC	PPRY	ITCH	287:290	Mutation rewiring degron network	0.0556
p.S283C	DO37951	SKCM	ICGC	PPRY	ITCH	287:290	Mutation rewiring degron network	0.2222
p.S282L	DO41020	UCEC	ICGC	PPRY	ITCH	287:290	Mutation rewiring degron network	0.1944
p.S296Y	DO41572	UCEC	ICGC	PPRY	ITCH	287:290	Mutation rewiring degron network	0.1667
p.Q282H	SIDM01432	Kidney Carcinoma	GDSC	PPRY	ITCH	287:290	Mutation rewiring degron network	0.1944
p.T286P	CML-T1	haematopoietic and lymphoid tissue	COSMIC	PPRY	ITCH	287:290	Mutation rewiring degron network	0.3056
p.I299V	CCK-81	large intestine	COSMIC	PPRY	ITCH	287:290	Mutation rewiring degron network	0.0833

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*NOTE: the Kaplan plots were collected from OncoLnc