DegronMD - O43719(HTATSF1)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.D91V	TCGA-86-8056	LUAD	TCGA	ASSST	DEG_SPOP_SBC_1	82:86	Mutation rewiring degron network	0.1944
p.D91V	DO24950	LUAD	ICGC	ASSST	DEG_SPOP_SBC_1	82:86	Mutation rewiring degron network	0.1944
p.D80N	TCGA-AP-A1DV	UCEC	TCGA	ASSST	DEG_SPOP_SBC_1	82:86	Mutation rewiring degron network	0.2778
p.D80N	DO43186	UCEC	ICGC	ASSST	DEG_SPOP_SBC_1	82:86	Mutation rewiring degron network	0.2778
p.E90D	TCGA-AX-A1CE	UCEC	TCGA	ASSST	DEG_SPOP_SBC_1	82:86	Mutation rewiring degron network	0.2222
p.E90D	DO42280	UCEC	ICGC	ASSST	DEG_SPOP_SBC_1	82:86	Mutation rewiring degron network	0.2222
p.A82T	TCGA-BR-8284	STAD	TCGA	ASSST	DEG_SPOP_SBC_1	82:86	Mutation altering degron motif	0.7139
p.A82T	TCGA-DU-6392	LGG	TCGA	ASSST	DEG_SPOP_SBC_1	82:86	Mutation altering degron motif	0.7139
p.A82T	DO22237	LGG	ICGC	ASSST	DEG_SPOP_SBC_1	82:86	Mutation altering degron motif	0.7139
p.A82T	DO228138	PBCA	ICGC	ASSST	DEG_SPOP_SBC_1	82:86	Mutation altering degron motif	0.7139
p.A82T	DO38491	STAD	ICGC	ASSST	DEG_SPOP_SBC_1	82:86	Mutation altering degron motif	0.7139
p.A82T	SIDM00216	Colorectal Carcinoma	GDSC	ASSST	DEG_SPOP_SBC_1	82:86	Mutation altering degron motif	0.7139
p.A82T	SIDM00118	Colorectal Carcinoma	GDSC	ASSST	DEG_SPOP_SBC_1	82:86	Mutation altering degron motif	0.7139
p.A82T	ACH-000989	Colon/Colorectal Cancer	CCLE	ASSST	DEG_SPOP_SBC_1	82:86	Mutation altering degron motif	0.7139
p.A82T	ACH-001081	Colon/Colorectal Cancer	CCLE	ASSST	DEG_SPOP_SBC_1	82:86	Mutation altering degron motif	0.7139
p.A82T	SNU-175	large intestine	COSMIC	ASSST	DEG_SPOP_SBC_1	82:86	Mutation altering degron motif	0.7139
p.A82T	HCC2998	large intestine	COSMIC	ASSST	DEG_SPOP_SBC_1	82:86	Mutation altering degron motif	0.7139
p.S85Y	TCGA-CA-6718	COAD	TCGA	ASSST	DEG_SPOP_SBC_1	82:86	Mutation altering degron motif	0.712
p.S85Y	DO7801	COAD	ICGC	ASSST	DEG_SPOP_SBC_1	82:86	Mutation altering degron motif	0.712
p.D91H	TCGA-CN-4741	HNSC	TCGA	ASSST	DEG_SPOP_SBC_1	82:86	Mutation rewiring degron network	0.1944
p.D91H	DO14313	HNSC	ICGC	ASSST	DEG_SPOP_SBC_1	82:86	Mutation rewiring degron network	0.1944
p.A73T	TCGA-NH-A50T	COAD	TCGA	ASSST	DEG_SPOP_SBC_1	82:86	Mutation rewiring degron network	0.0833
p.A73T	DO44086	COAD	ICGC	ASSST	DEG_SPOP_SBC_1	82:86	Mutation rewiring degron network	0.0833
p.A94S	DO229025	LICA	ICGC	ASSST	DEG_SPOP_SBC_1	82:86	Mutation rewiring degron network	0.1111
p.S78F	DO222696	MELA	ICGC	ASSST	DEG_SPOP_SBC_1	82:86	Mutation blocking phosphorylation signal	0.6667
p.E90K	DO222749	MELA	ICGC	ASSST	DEG_SPOP_SBC_1	82:86	Mutation rewiring degron network	0.2222
p.E90G	SIDM00967	Ovarian Carcinoma	GDSC	ASSST	DEG_SPOP_SBC_1	82:86	Mutation rewiring degron network	0.2222
p.E90G	ACH-002181	Ovarian Cancer	CCLE	ASSST	DEG_SPOP_SBC_1	82:86	Mutation rewiring degron network	0.2222
p.E90G	OVCA420	ovary	COSMIC	ASSST	DEG_SPOP_SBC_1	82:86	Mutation rewiring degron network	0.2222

Kaplan plot for HTATSF1 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

HTATSF1

UniProt ID: O43719

Entrez ID: 27336

Protein name: HIV Tat-specific factor 1 (Tat-SF1)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for HTATSF1 in