DegronMD - O43900(PRICKLE3)

PRICKLE3

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S542L	TCGA-21-5782	LUSC	TCGA	PSSSS	DEG_SPOP_SBC_1	549:553	Mutation blocking phosphorylation signal	0.5833
p.S546F	TCGA-A5-A1OF	UCEC	TCGA	PSSSS	DEG_SPOP_SBC_1	549:553	Mutation rewiring degron network	0.25
p.E555K	TCGA-AX-A2HC	UCEC	TCGA	PSSSS	DEG_SPOP_SBC_1	549:553	Mutation rewiring degron network	0.2778
p.E555K	TCGA-C5-A1BI	CESC	TCGA	PSSSS	DEG_SPOP_SBC_1	549:553	Mutation rewiring degron network	0.2778
p.D559N	TCGA-B5-A0JY	UCEC	TCGA	PSSSS	DEG_SPOP_SBC_1	549:553	Mutation rewiring degron network	0.1667
p.R540G	EB2	haematopoietic and lymphoid tissue	COSMIC	PSSSS	DEG_SPOP_SBC_1	549:553	Mutation rewiring degron network	0.0833

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*NOTE: the Kaplan plots were collected from OncoLnc