DegronMD - O60291(MGRN1)

MGRN1

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P384H	TCGA-G7-6792	KIRP	TCGA	PPGY	ITCH	383:386	Mutation altering degron motif	0.7694
p.R375K	DO223407	CLLE	ICGC	PPGY	ITCH	383:386	Mutation rewiring degron network	0.1111
p.S385L	DO16101	HNSC	ICGC	PPGY	ITCH	383:386	Mutation altering degron motif	0.7667
p.S385L	DO219221	LUSC	ICGC	PPGY	ITCH	383:386	Mutation altering degron motif	0.7667
p.E390K	DO218943	LUAD	ICGC	PPGY	ITCH	383:386	Mutation rewiring degron network	0.2222
p.R377L	DO26518	LUSC	ICGC	PPGY	ITCH	383:386	Mutation rewiring degron network	0.1667
p.S395P	DO37308	READ	ICGC	PPGY	ITCH	383:386	Mutation rewiring degron network	0.0833
p.A394V	SIDM02035	Colorectal Carcinoma	GDSC	PPGY	ITCH	383:386	Mutation rewiring degron network	0.1111
p.E387Q	SIDM00032	Bladder Carcinoma	GDSC	PPGY	ITCH	383:386	Mutation rewiring degron network	0.3056
p.E387Q	ACH-000839	Bladder Cancer	CCLE	PPGY	ITCH	383:386	Mutation rewiring degron network	0.3056
p.E387Q	SCaBER	urinary tract	COSMIC	PPGY	ITCH	383:386	Mutation rewiring degron network	0.3056
p.A378T	KCL-22	haematopoietic and lymphoid tissue	COSMIC	PPGY	ITCH	383:386	Mutation rewiring degron network	0.1944

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*NOTE: the Kaplan plots were collected from OncoLnc