DegronMD - O75208(COQ9)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S76F	TCGA-AG-A002	READ	TCGA	PPRY	ITCH	79:82	Mutation rewiring degron network	0.25
p.S76F	DO222578	MELA	ICGC	PPRY	ITCH	79:82	Mutation rewiring degron network	0.25
p.G87S	TCGA-AZ-6598	COAD	TCGA	PPRY	ITCH	79:82	Mutation rewiring degron network	0.1944
p.G87S	DO10276	COAD	ICGC	PPRY	ITCH	79:82	Mutation rewiring degron network	0.1944
p.D92G	TCGA-CK-4951	COAD	TCGA	PPRY	ITCH	79:82	Mutation rewiring degron network	0.0556
p.D92G	DO10582	COAD	ICGC	PPRY	ITCH	79:82	Mutation rewiring degron network	0.0556
p.Y82F	TCGA-CV-7568	HNSC	TCGA	PPRY	ITCH	79:82	Mutation altering degron motif	0.7528
p.Y82F	DO14160	HNSC	ICGC	PPRY	ITCH	79:82	Mutation altering degron motif	0.7528
p.E74D	DO229045	LICA	ICGC	PPRY	ITCH	79:82	Mutation rewiring degron network	0.1944
p.S76C	DO47168	RECA	ICGC	PPRY	ITCH	79:82	Mutation rewiring degron network	0.25
p.Q85L	SIDM00311	Mesothelioma	GDSC	PPRY	ITCH	79:82	Mutation rewiring degron network	0.25
p.Q85L	ACH-002133	Lung Cancer	CCLE	PPRY	ITCH	79:82	Mutation rewiring degron network	0.25
p.Q85L	H2810	pleura	COSMIC	PPRY	ITCH	79:82	Mutation rewiring degron network	0.25
p.E69D	SIDM00534	Colorectal Carcinoma	GDSC	PPRY	ITCH	79:82	Mutation rewiring degron network	0.0556
p.E69D	ACH-000986	Colon/Colorectal Cancer	CCLE	PPRY	ITCH	79:82	Mutation rewiring degron network	0.0556
p.E69D	HT-115	large intestine	COSMIC	PPRY	ITCH	79:82	Mutation rewiring degron network	0.0556
p.E91D	SIDM01617	Endometrial Carcinoma	GDSC	PPRY	ITCH	79:82	Mutation rewiring degron network	0.0833
p.E91D	ACH-000994	Endometrial/Uterine Cancer	CCLE	PPRY	ITCH	79:82	Mutation rewiring degron network	0.0833

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons